Alzheimer's disease is not accelerated aging
...her, these point toward a disrupted network in the brains of patients with Alzheimer's disease, which includes the medial temporal lobe and other regions of the brain that undergo atrophy and reduced glucose metabolism, and appear to be involved in memory impairment. "We see profound disturbances in the med...Study explores gene transfer to modify underlying course of Alzheimer's disease
...laques (which are abnormal protein deposits in the brains of patients with Alzheimer's disease), and loss of synapses in the brains of Alzheimer's disease patients. Alzheimer's disease is a common disease in aging, currently affec...Amyloid fibers sprout one step at a time
...s are similar to the amyloid plaques that clog the brains of patients with Alzheimer's or Parkinson's disease. Unlike bacteria and viruses, prions consist only of aberrant proteins that misfold into forms that, in turn, induce normal proteins to misfold. In mammalian prion infections, these abnormal, insol...New sign language suggests children create language's fundamentals through learning
... (as Noam Chomsky, for example, has argued), their brains do use a specific approach to learning that can turn a simple communication system into a true language in a surprisingly short period of time. The researchers compared the ways that deaf children and adults used Nicaraguan Sign Language (NSL) to tel...Peering inside the body, with a new spinliterally
...sh. He also has taken disembodied mouse livers and brains for slow spins around the magnet, revealing chemical spectra in tissue up to 10 times the resolution seen in stationary NMR. But it's living tissue that holds the most promise for this method, Wind said, because there is no good way to see what is h...Molecule awakens and maintains neural connections
...revealed that the gene was highly expressed in the brains of embryonic mice. "A major reason we became interested in this molecule is that when we used antibody markers to look at the distribution of the protein, we saw it primarily in the dendrites, with very little in the axons," said Yuh Nung Jan. "If yo...A genetic disorder yields insight into genes and cognition
...unctional magnetic resonance imaging (fMRI) of the brains of 13 volunteers with WS, as they asked the volunteers to perform two perceptual tasks. Such fMRI imaging involves using harmless magnetic fields and radio waves to image blood flow in the brain, which reveals brain activity. In one set of experiment...Rare deficit maps thinking circuitry
...creased activation in that circuit. The patients' brains showed no difference from controls on tasks that activated the "what" circuit. Using structural MRI, the researchers found a small region early in the "where" circuit that lacked gray matter (neuron bodies) in the Williams Syndrome participants. Its...DHA-rich diet protects brain from Alzheimer's damage, UCLA study shows
... "We found high amounts of synaptic damage in the brains of the Alzheimer's-diseased mice that ate the DHA-...hese changes closely resembled those we see in the brains of people with Alzheimer's disease." Although the mice on the DHA-supplemented diet also carried...Decreasing toxins in brains of Alzheimer's patients keep cognitive deficits at bay
...anes and misfolded proteins that accumulate in the brains of Alzheimer's disease patients causes the death of cells involved in memory and language. Domenico Pratico, MD, Associate Professor of Pharmacology at the University of Pennsylvania School of Medicine, and colleagues have shown in a preliminary stud...Genetic clues found for common congenital brain disorder
...es in the cerebellum that were very similar to the brains of patients with Dandy-Walker. They also lacked coordination and were unable to right themselves if they fell over. Although the authors conclude that "heterozygous loss of ZIC1 and ZIC4 is the cause of Dandy-Walker malformation in deletion 3q2 pat...Sweet success in targeting sugar molecules to cells in living animals
...en some reports in changes of glycosylation in the brains of people who have prion disease or Alzheimer's disease," she said. Additional studies suggest that glycosylation patterns on embryonic cells may serve as developmental markers because they change as the embryo grows. Thus, studying changes in glycos...Scientist who discovered Sly syndrome finds new research path to explore for treating the disease
...e missing enzyme to treat Sly Syndrome reached the brains of baby mice, but not of brains of adults. "Here we report that the blood-brain barrier of neonatal mice possesses a transport syst......in low doses and with very few side effects in the brains of laboratory mice. The work opens an important door: Connexins found in high concentrations in the brain are believed to play a critical role in movement, vision and memory. To understand how these communication "tunnels" work, scientists must be ab...Early clinical treatment can halt progression of Alzheimer's disease, UCI researchers find
...ound that when we cleared amyloid plaques from the brains of mice, the downstream consequences of the disease were lessened and even removed, provided the disease had not progressed to a certain advanced state," said LaFerla, who is associate director of the UCI Institute for Brain Aging and Dementia. "Our ...Computer imaging of Archeopteryx skull suggests this dinosaur-bird link could fly
...ny modern birds. "There are living birds that have brains that are relatively smaller than Archeopteryx ," Rowe said. Birds are thought to need significant brain power because of the specialized visual and other requirements of flight. High flyers, for example, need to coordinate information coming from th...Depression traced to overactive brain circuit
...pressed. Researchers discovered the abnormality in brains of those whose depressions relapsed when a key bra...nced a temporary recurrence of symptoms when their brains were experimentally sapped of tryptophan, the chemical precursor of serotonin, the neurotransmitter ......ealth, researchers studied chemical changes in the brains of mice and rats injected with leptin to arrive at their findings. The Brown/Rhode Island Hospital research team included Nillni and Ronald Stuart. Christian Bjorbaek, Li Guo and Heike Munzberg worked on the project through Harvard and the Beth Is-ra...Mouse brain stem cells capable of converting into blood vessel cells
Adult stem cells in the brains of mice possess a broader differentiation potentia... same neural stem cells were transplanted into the brains of mice early in development....Sleepless over Seattle: Migrating songbirds forgo sleep but keep their wits
... movement in the cages and placed sensors on their brains to monitor their sleep patterns across the seasons. During the times the birds would normally be migrating, they slept about a third as much as usual and entered more quickly into REM sleep, the stage of sleep typically associated with dreaming in hu...