NICHD funded researchers first to genetically modify non human primate
...ces University in Portland, Oregon. "This research breaks a technical barrier," said NICHD Director Duane Alexander, M.D. "The technology paves the way for developing new models for testing treatments for a variety of diseases in a more relevant way than is currently possible." Although scientists have oft...Atmospheric chemistry key to global and local air pollution
... respiratory problems and eye irritation. Sunlight breaks ozone apart resulting in the creation of the very ...ollutant nitric oxide produces ozone. The sun then breaks down this ozone, creating hydroxl radicals and starting the cycle all over again." Brune is part of ...Drug decreases blood vessel stiffness in older primates
A novel drug that breaks down vascular collagen bonds in the body significantly decreased the stiffness of blood vessels in older non-human primates, according to a study conducted by National Institute on Aging (NIA) scientists and others.* The finding suggests the medicat...UCSF-led study points to pivotal, early event in cancer development
...singularly focused on proliferating and eventually breaks out of its tissue membrane. (See image: http://pubaffr.ucsf.edu/imagedb/imsearch.php3?iname=0130200118 ) The genesis for the researchers' investigation was, in part, to seek an explanation for why the majority of cancers originate in epi...US and Japanese scientists develop new test for male infertility
...tin. Ubiquitination is a process by which the body breaks down and recycles obsolete cellular proteins. The accumulation of ubiquitin in the sperm cells is evidence of damage or defect. The researchers used specific antibodies against ubiquitin to screen sperm from 17 infertility patients and two fertile d...New technique answers one of waters basic mysteries
... than a billionth of a second later, the formation breaks and the proton either falls back to the central molecule, or its path is cut off and it roams as a free proton. Though this occurrence is extremely rare for any one molecule, there are countless molecules in a single glass of water, so the process ha......he proton away, by accident the hydrogen bond wire breaks and this proton is stuck off in left field." Once the proton is liberated, it wanders through the liquid, free to participate in many other chemical reactions until it recombines with an hydroxide ion to make water again. Concentrations of hydrogen i...Amoebas use "midwives" to reproduce
...at their connecting tether, stretching it until it breaks and each can start a life of its own. In the second scenario, the two tug at the tether but fail to disconnect. After a while they give up, and revert to being a single cell, which now has two nuclei. A collaborative study by physicists and biologist...Spurred by the worldwide fight against malaria, scientists release parasite genome database
...ty of Pennsylvania, the Plasmodium genome database breaks new ground in bioinformatics by permitting detailed analysis of a genome even before its sequencing is complete. "The release of this database is, in some respects, more important for malaria researchers than the sequencing of the human genome has...Saline solution a serious threat to wetlands
...out 50 km along its length it gets very narrow and breaks into two. The southern lagoon is the bottom half of it," he said. This lagoonal system is known as the Coorong. As you move along it from the mouth, its salinity increases well beyond the level of seawater. "It's a natural laboratory," said Dr Pato...Carbon monoxide has unexpected benefits, but don't try it at home
...ss in which an enzyme called heme oxygenase type 1 breaks down vital molecules called hemes, when the cells carrying them wear out. Through as-yet poorly understood mechanisms, heme oxygenase type 1 levels rise during ischemia, stepping up this process and increasing carbon monoxide levels. Carbon monoxide...Ohio State chemists synthesize possible new anti-tumor agent
... 1986. The natural form of the chemical breaks down too quickly for scientists to test whether it could be used to combat cancer cells in the body. Now that Ohio State researchers have completed ......s critical to wildlife. The approach dramatically breaks with both traditional conservation policies and common agriculture techniques. The report, Common Ground, Common Future: How Ecoagriculture Can Help Feed the World and Save Wild Biodiversity, provides for the first time a comprehensive summary of t...New finding accelerates discovery of disease genes and human population history
...ts shorter as random shuffling between chromosomes breaks it down. The size of modern blocks of linkage disequilibrium thus indicates when the population last contracted to a small size," says Reich. "The 8-times larger blocks of linkage disequilibrium in northern Europeans thus suggest a relatively recent ...Key step in gene activation discovered
...ed "SWI/SNF" (pronounced "switch-sniff"). SWI/SNF breaks the grip of the histone proteins in the core of the nucleosome spool, liberating the gene on that stretch of DNA so it can unwind far enough to be accessible to another molecule, the "Transcription Enzyme," whose job is to move along the gene's lengt...When Shewanella meets goethite: Evidence found of recognition between animate and inanimate objects
...rons to the mineral. The addition of each electron breaks a bond between atoms on the mineral's surface and allows the goethite to shed iron. Its surface molecules convert from iron3 (Fe III) to iron2 (Fe II). The result can be iron shed into ground water. Or, if a toxic metal, such as lead or arsenic, is b...Tea fights cavities, reduces plaque
...bacteria stopped growing and producing acid, which breaks down the teeth and causes cavities. This research supports an earlier Swedish study that found rinsing the mouth with black tea significantly reduced plaque build-up. "It is our belief of these researchers that the intake of black tea can be signfi...... he says. It gets rid of abnormal proteins, and it breaks down and recycles regulatory proteins no longer ne... in some diseases, the ubiquitin-proteasome system breaks down. Huntingtin aggregates, for example, contain thousands of misfolded proteins with ubiquitin fla...Dopamine-dampening gene linked to prefrontal inefficiency, schizophrenia
...being involved because it codes for an enzyme that breaks down dopamine after it is secreted into the synapse. People inherit two copies of COMT (one from each parent), each in either of two forms. The most common variant, val, reduces prefrontal dopamine activity, while a somewhat less common form, met, ...... that models a genetic disease of the protein that breaks down fatty acids," said Ibdah. In a knockout mouse, a specific gene is removed from the rodent, modeling the disease process in people who are born without that particular gene. "Our results demonstrate that the mitochondrial-trifunctional-prot...