Chemical derived from vitamin-E shows early promise as cancer drug
...r acetic analog (alpha-TEA), to prevent colon and breast cancers in preclinical animal models. Mice in t...Nutrition, also investigated how alpha-TEA impacts breast cancer cells, using cells grown in plastic containers. When exposed to alpha-TEA, the cancer cells s...Safety of isoflavones in dietary supplements targeted by Illinois initiative
...ve of postmenopausal women with estrogen-dependent breast cancer. "Under the grant, three groups will co...g roles. Helferich will continue a focus on breast cancer. He recently found that isoflavones can block the effectiveness of tamoxifen in reducing est...Phase II trials of second-generation antisense cancer drug planned following successful early study
...ients with metastatic hormone refractory prostate, breast and lung cancer. Phase II breast and prostate studies will begin near the end of the year, and a Phase I lung cancer trial started th...High resolution satellite imagery assists hunt for infectious 'kissing bugs'
...ted food, mother to child transmission like during breast feeding and tainted blood transfusions. Infection by this Trypanosoma cruzi parasite may cause short-term symptoms including fever, tiredness and brain swelling. However it is the longer-term symptoms that are most serious: ten to 15 years after init...Evidence builds for potential new cancer drug target
...team but not yet published, c-myb was deleted from breast tissue. The researchers believe that this gene plays a critical role in breast cancer and want to show the effects of its deletion on breast tumor cell proliferation. The group'...Certain genes boost fish oils' protection against breast cancer
...earchers who found that fish oils appear to reduce breast cancer risk have now discovered that the oils may ... with certain common DNA patterns experienced more breast cancer protection from marine n-3 fatty acids than women with other common patterns," explained Manu...Experimental drug shown to block mutant protein causing blood disease
...ch causes misshapen skull, face, fingers and toes, breast and pancreatic cancers, and brain tumors....New anti-inflammatory strategy for cancer therapy identified by UCSD researchers
...ancer Center. The studies in mice with colon or breast cancer showed that cancer metastasis, the growth o... Mice used in the new study were given colon or breast tumor cells which metastasized to the lung. Some of these cancer cells served as "controls," while ...Charting the future in prostate cancer care: A call to action
...rch has lagged behind other areas, such as that of breast cancer, where there has been recent progress in integration among specialties and late-stage innovation of new therapeutics. On September 22, 2004, the Prostate Cancer Foundation (PCF) will release its Report to the Nation on Prostate Cancer, authore...Diabodies act as guided missiles targeted to mammary tumor growth
...umor-busting radiation thwarts the growth of human breast cancer in laboratory animals, according to researc...-A significantly inhibits the growth rate of human breast tumor xenografts in mice. "The diabodies bound to the HER2 receptor produced by certain breast tumo...Flame retardants found on supermarket shelves
...earchers recently reported high levels of PBDEs in breast milk of 47 women in Dallas and Austin the highest levels found in the world to date. They selected three major supermarket chains in Dallas for the new study and sampled well-known brands, assuming these were foods the women would probably have eate...Select research highlights from current AACR journals
... steroid synthesis used to treat hormone-dependent breast cancer in postmenopausal women pack a significant beneficial side effect in laboratory animals. Exemestane and letrozole was shown to significantly prevent bone loss, enhance bone mechanical strength and lower serum cholesterol levels. The inhibitor ...Anti-cancer compound in vegetables found to block late-stage breast-cancer cell growth
...ective in disrupting late stages of cell growth in breast cancer. Keith Singletary and doctoral student Stev...be used to enhance the prevention and treatment of breast cancer, in the September issue of the Journal of Nutrition. "This is the first report to show how th...Synthesized molecules studied as weapon to stop cell division in cancer cells
...t would probably be particularly effective against breast cancer and prostate cancer. It seems to relate to secondary sexual characteristics." However, a lot of work remains to be done to develop a drug, she cautions. "For instance, the inhibitor does not cross cell membranes. We can overcome that in the la...New compound could give some types of cancer the one-two punch
...ol, which is used to kill cancer cells in ovarian, breast and lung tissue. Drugs like Taxol come from natural sources, and supplies are sometimes extremely limited. Also, synthetic versions of these drugs can be very difficult to make. Providing a drug with more than one effect could also benefit cancer pat...Livermore research in accelerator mass spectrometry highlighted at ACS meeting
...l biomarkers for atherosclerosis, DNA oxidation in breast cancer cells, pharmacokinetics and development of ...e use of AMS to detect a new type of DNA damage in breast cancer cells. Charles Westbrook of the Chemistry and Materials Science (CMS) Directorate will discus...Study suggests cell-cycle triggers might be cancer drug targets
...howing that mice lacking cyclin D1 had very little breast tissue and, when crossed with cancer-prone mice, had offspring that were largely protected against breast cancer. It was those and other findings that raised the prospect of cancer therapy using drugs to bl...Progress in breast cancer progression
...colleagues, from Ulm University in Germany, used a breast cancer model system to show that a protein called ...NF-kB pathway in nude mice that were injected with breast cancer cells. Under these conditions, these breast cancer cells were unable become metastatic, unl...JCI table of contents, 16 August, 2004
...colleagues, from Ulm University in Germany, used a breast cancer model system to show that a protein called ...NF-kB pathway in nude mice that were injected with breast cancer cells. Under these conditions, these breast cancer cells were unable become metastatic, unli......d cancer stem cells in acute myelogenous leukemia, breast cancer and two types of brain cancer. The current ...s inappropriately activated is also susceptible to breast cancer. He said that many proteins in addition to beta-catenin are involved in the Wnt pathway, any ...