The telomere crisis: A crucial stage in breast cancer
... is an important early event in the development of breast cancer, and its occurrence can be identified with ...ogress further, it next invades other parts of the breast and may escape to other organs. Not all cancer researchers agree that telomere crisis in hyperplas...Small animal imaging gives cancer clues
... to ductalcarcinoma in situ (DCIS), a precursor to breast cancer in humans. "With non-invasive imaging, we ...tolook for small treatment effects. Most invasive breast cancers are thought to develop from DCIS, andstandard care is to remove the entire area involved, Bo...Genetic mutation linked to more aggressive breast cancer found more often in African-Americans
...r suppressor gene called p53 are more prevalent in breast cancer of African-American women than white women,... prevalence of p53 alterations in African-American breast cancer patients," according to an accompanying editorial. Free abstracts of the study and editorial ...More aggressive breast cancer tumors found in African American women
...etic mutation related to a more aggressive form of breast cancer occurs four times more often in African Ame..., African-American women have a lower incidence of breast cancer than white women, but they have a higher mortality rate. The disease also develops at an earl...Alterations in vitamin D receptor gene increase prostate, breast cancer risk
...on of the sunshine vitamin, increasing the risk of breast cancer in Caucasian women and prostate cancer in A...r initiation and progression. For example, in the breast cancer study, British scientists at St. George's Hospital Medical School in London found that Caucas...Study links high carbohydrate diet to increased breast cancer risk
...rb-conscious dieters may be lowering their risk of breast cancer while they're shedding pounds, based on the...nergy intake from carbohydrates incurred a risk of breast cancer 2.2 times higher than women with more balanced diets. Dietary patterns in Mexico are charact...Other highlights in the August 4 JNCI
...ssociated with an increased risk of postmenopausal breast cancer in overweight and obese women, according to...nce, and hypertension. Both metabolic syndrome and breast cancer have been increasing worldwide. Increased levels of insulin and insulin-like growth factor in...From science fiction to reality: Nanomedicine brings fresh hope to the medical world
...igh-content drug screening and in the detection of breast cancer cells among others. However, as with other new technologies, nanomedicine also faces its own set of issues. Scalability is one of its biggest technological challenges. While large-scale production makes better economic sense, this is likely to...Clusters of alterations on PIK3CA gene found in brain cancers
... and they are also present, to a lesser extent, in breast and lung cancer," Yan noted. "Our studies defined the association of mutant PIK3CA gene in a wider spectrum of adult and pediatric brain tumors as well." PIK3CA is part of a family of genes that encode lipid kinases, enzymes that modify fatty molecul...LA BioMed Medical/Research Briefs, July/August 2004
...more explanation as to why more black women die of breast cancer than white women, despite the evidence of breast cancer incidence being higher among white women. According to LA BioMed investigator Rowan Chelbows...UCI study reveals gene linked to breast cancer can suppress tumors
...tion for a gene that, when mutated, often triggers breast cancer in women. The work also provides further e...thy BRCA1 gene prevents the growth and survival of breast cancer cells. The gene accomplishes this by keeping estrogen and growth factor molecules from sendin...Virtual counselor supplements traditional genetic counseling
...one genetic counseling for increasing knowledge of breast cancer and genetic testing among women at low risk for breast cancer. Counselors were, however, more effective than the computer program at reducing women's...NIH renews funding for continued Rb2 tumor suppressing gene research at Temple
...aries, the effectiveness of drug therapies against breast cancer, and as a potential prognosticator of prostate cancer. "The grant from NIH is recognition of our hard and creative work on Rb2/p130 over the past 12 years," says Giordano. "With this funding, we will be able to attain a more in-depth unders...Microarrays, key genome expression trackers, work better when probes are sequence-verified
...obe sequence accuracy in data from two independent breast cancer expression profiling studies. Their results...lated to the underlying biology (in this data set, breast cancer) as opposed to the source of the experiments. "As combining data from multiple microarray pl...Researchers uncover surprising degree of large-scale variation in the human genome
...implicated in leukemia and drug resistant forms of breast cancer. In addition, some CNPs identified genes with known influence on 'normal' human phenotypes including oneneuropeptide-Y4 receptorthat is directly involved in the regulation of food intake and body weight. According to the study, a relation...Maternal DHA levels plays important role in infant development
...he third trimester. DHA is also found naturally in breast milk and has recently been added to some U.S. commercial infant formulas. Some research indicates this postnatal DHA improves vision and some cognitive functions in infants and toddlers, although the evidence is mixed. In this study, we measured DHA...Patients' cells from tumors, the immune system merged for customized cancer therapy
...ering patients' immune response against kidney and breast cancer. In a paper published in the July 15 issue...d research team documented tumor regression in two breast cancer patients, and stabilization and containment of tumor growth in late stage breast and kidney p...Protective mechanism exploited by tumors may provide new cancer treatment
...y be that tumors try different mechanisms and some breast cancers, colon cancers, melanomas or whatever hit on this particular strategy." The idea of using this strategy against tumors began in 1998 when MCG scientists reported in Science that the fetus used IDO indoleamine 2,3-dioxygenase to locally disa...Anti-cancer agent built from anti-inflammatory drug
... have evidence that it may sensitize leukemia, and breast and lung cancers to conventional chemotherapy." The new agent is based on the drug celecoxib, a nonsteroidal anti-inflammatory drug, or NSAID. Like many NSAIDs, celecoxib also reduces the risk of colorectal cancer when taken regularly. Scientists kne...Animal research suggests plant estrogens in soy do not increase breast cancer risk
...trogens found in soy does not increase the risk of breast or uterine cancer in postmenopausal women. "This ...e especially interesting to women at high risk for breast cancer who take soy products." The research is reported in the current issue of The Journal of Clini...