Researchers unlock key secrets showing how tumors hide from immune system
...n inhibiting Stat3 for more effective treatment of breast cancer, prostate cancer, sarcoma, melanoma and other tumors that harbor aberrantly activated Stat3....BRCA mutations not associated with colorectal cancer risk, studies suggest
...on, have been associated with an increased risk of breast and ovarian cancer, but it is unclear whether thes...isk of colorectal cancer. A family history of breast cancer in a female relative was not associated with an increased risk of colorectal cancer, even aft...BRCA mutations do not increase risk of colorectal cancer
...ith mutations in BRCA genes or a family history of breast cancer now have one less thing to worry about. Although their chances of developing breast or ovarian cancer are high, new research shows their colorectal cancer risk is about the same as tha...Vegetables that prevent may ultimately cure some cancers
... altered DIM from broccoli came when the growth of breast cancer cells was inhibited in laboratory studies. Subsequent research showed these compounds also inhibited growth of pancreatic, colon, bladder and ovarian cancer cells in culture, Safe said. Limited trials on lab mice and rats have produced the sim...OHSU team discovers compound that lacks estrogen's risks
...loxifene, used for the prevention and treatment of breast cancer and osteoporosis, respectively. STX mimics the effects of estrogen by activating a novel rapid signaling pathway, discovered by Kelly and Rnnekleiv, in nerve cells of the hypothalamus. The hypothalamus is a thumb-sized, central area on the u...Candy canes, sugarplums or licorice for Christmas? Only one might stop cancer
... the laboratory on tissues taken from prostate and breast cancer tumors. "We were able to conclusively demo...stopped the growth of cancer cells in prostate and breast cancers," Rafi said. Prostate and breast cancers are the leading cancers affecting men and women re...Traditional Christmas snack under threat
...ters in height and 16.5 meters in circumference at breast height. The scientists surveyed 23 natural Brazil nut tree populations in the Brazilian, Bolivian and Peruvian Amazon, and found that populations that have been extensively harvested over several to many decades are dominated by older trees, with ve...Oral drug showing promise for breast cancer prevention in a mouse model
...the development of estrogen receptor (ER)-negative breast cancer in a mouse model, which raises the possibil...e drug could be a preventive agent for ER-negative breast cancer. The results appear in the December 17 issue of the Journal of the National Cancer Institute...Other highlights in the December 17 issue of JNCI
...odality alone for premenopausal lymph nodenegative breast cancer: A randomized trial: http://www.eurekalert.org/emb_releases/2003-12/jotn-sst121103.php...Combining various magnetic resonance imaging techniques may help improve breast cancer detection
...ore accurately sorts cancers from benign masses in breast tissues than any single imaging techniques. Their .... Eighteen already had been diagnosed with benign breast lesions, and 18 with breast cancer. The researchers reviewed the results of the combined images wi...The 4th European Breast Cancer Conference (EBCC4)
An invitation to Europe's largest forum on breast cancer The 4th European Breast Cancer Conference (...m in Europe that involves all the major players in breast cancer. The conference is unique in encouraging interaction between clinicians and patients in a par...Novel therapies show promise against myeloid leukemia
...directly inhibited the growth of both melanoma and breast carcinoma cells in experiments in vitro (in tissue cultures). When researchers intravenously (IV) injected IFN-MSC (four doses of 106 MSC/week) into mice with metastatic lung cancers, tumor growth was inhibited and survival of the animals doubled. ...Scientists solve puzzle of how kinesin motor molecules walk or limp across cells
... For example, taxol, a drug commonly used to treat breast cancer, works by stabilizing the microtubules that kinesins walk along and preventing them from de-polymerizing, Block noted. Recent studies also have shown that certain viruses, including smallpox and herpes, infect cells by hitching a ride on kine...Origin of multiple myeloma found in rare stem cell
... development may apply to other cancers, including breast cancer, acute myeloid leukemia and acute lymphocytic leukemia. Multiple myeloma is the second most common blood cancer and strikes more than 14,000 Americans each year. Close to 11,000 will die from the disease. ...Findings offer clue to how molecule can both stimulate, suppress cell growth
...th suppressor. Since that time, its role in colon, breast and other cancers has been studied extensively at Vanderbilt and elsewhere. Now a team of researchers at Vanderbilt-Ingram has found a clue to the seemingly contradictory biological actions of TGF-b. Their findings are published online this week by ...Tamoxifen's effectiveness may be compromised by hot flash drug
... a therapy used in the treatment and prevention of breast cancer, may be limited by the use of a commonly pr...y women as part of standard therapy for those with breast cancer and those at high risk of developing the disease. For about 80 percent of the women who take ...Protein involved in cell division now found key to cell growth
...e highly over-expressed in many tumors, such as in breast and ovarian cancers, but no one knows why that is or how to control it," says Zhang. "Now we at least know that ARF can control B23, and it may mean a drug that mimics ARF could help inhibit the protein and help control cell growth." Cells that grow...Breast cancer susceptibility genes play role in DNA repair
...r the tumor suppressor proteins BRCA1 and BRCA2 in breast cancer. The findings, presented in November issue ...side BRCA1 and BRCA2 and might also play a part in breast cancer. These proteins offer an important set of new targets for possible anti-cancer drugs. The lin...Scientists discover potential approaches to enhance existing cancer therapies
...ue that may help physicians select which recurrent breast cancer patients are most likely to respond to horm...l trial at NYU. Estrogen receptor (ER) imaging in breast cancer using [F-18]-fluoroestradiol (FES) PET: predicting the response of advanced disease to endocr......g cancer. The number exceeds the combined total of breast cancer (39,800) uterine cancer (10,900) and ovarian cancer (14,300). Women smokers are 20 to 70 percent more likely to develop lung cancer than are men smokers, at the same level of exposure. Studies have shown that women are largely unaware of the...