Tag: "bred" at biology news

Newly identified master gene key in baby's first breath

...ich in turn produces surfactant. Researchers bred mice with and without the Foxa2 gene. When the gene was deleted, the knockout mice developed all the signs and symptoms of respiratory distress syndrome on the first day of life and died within hours of birth. The few knockout mice that did survive, ...

JCI table of contents September 15, 2004

...ues, of Kyoto University Faculty of Medicine, have bred an ath-erosclerotic mouse model (apoE/) with mice that were deficient in either the PGI receptor (IP) or the TXA receptor (TP). These mice allowed the authors to examine the effect of loss of PGI or TXA action on atherosclerosis development. Relativ...

Picking prostanoids to provide protection

...ues, of Kyoto University Faculty of Medicine, have bred an ath-erosclerotic mouse model (apoE/) with mice that were deficient in either the PGI receptor (IP) or the TXA receptor (TP). These mice allowed the authors to examine the effect of loss of PGI or TXA action on atherosclerosis development. Relati...

DHA-rich diet protects brain from Alzheimer's damage, UCLA study shows

... that enable memory and learning. By using mice bred with genetic mutations that cause the brain lesions linked to advanced Alzheimer's disease, the UCLA researchers created a mouse model to test environmental risk factors for the disorder. When the mice developed the lesions, but showed minimal memor...

UCSD researchers are first to demonstrate molecular link between inflammation and cancer

... given to two additional groups of mice one group bred without IKK beta in the epithelial cells of the in...SD team found that apoptosis was increased in mice bred without IKK beta. Specifically, without NF-kB activation, there was an increase of pro-apoptotic pr...

OHSU scientists find gene influencing drug withdrawal

...ce, OHSU School of Medicine, found Mpdz using mice bred to possess a region of a chromosome known to be associated with a predisposition to physical dependence and withdrawal from sedative-hypnotics like alcohol and barbiturates. During the four-year search, the scientists narrowed the initial field of mo...

Mice with hyperactive Wnt10b gene eat all they want, but have half the body fat of normal mice

...d the transgene DNA into fertilized mouse eggs and bred mice that inherited the new gene to create the animals used in our study. Under the control of the FABP4 promoter, fatty tissue in the transgenic mice contained 50 times the amount of Wnt10b found in adipose tissue from normal mice." Longo and MacDou...

The mother lode of mutations

...mine its function. The mother-who is the mutant-is bred with a male non-mutant. "All of her progeny are affected because the father doesn't provide any mutant genes," explains Mullins. "It's the mother who's providing what's in the egg." The Mullins group can ultimately identify the genes because the almo...

Survival of the fastest: scientists 'selectively breed' winning Formula One cars

...hose parameters. These winning solutions were then bred to produce the next generation, which combined the best settings of both parent cars until eventually we evolved the ultimate Formula One vehicle setup." Genetic algorithms are an emerging technology that unites the fields of biology and computer sci...

Genetic modification in mice lowers cholesterol and homocysteine by half

... or the PEMT pathway, the mice appeared normal and bred normally. But in each case, whether the CT or the PEMT pathway was missing, levels of lipoproteins were decreased by as much as half. This suggests, said Dr. Vance, that pharmacological inhibition of the manufacture of PC in the liver might be a...

New laboratory model can be used to test new treatments for pediatric eye cancer

...ce do not develop other types of cancer and can be bred to pass on the genetic mutations. This allows researchers to breed a large enough population to conduct drug trials. "Only about 300 children develop retinoblastoma in the United States each year," Dyer said. "It's very difficult to gather enough ch...

Cranberry breeding program may soon bear fruit for growers

...ompetitive edge. The berries of HyRed, a cranberry bred and tested for more than 10 years by UW-Madison plant breeders Eric Zeldin and Brent McCown, turn deeply red a full two weeks sooner than those of a leading cranberry cultivar called Stevens. HyRed's early and intense fruit color promises to help Mid...

Solving the mystery of the dancer mice, and cleft lip too

...etic defect resides, graduate student Jeffrey Bush bred many litters of mice and monitored the offspring for head-tossing and other Dancer signs. Through meticulous analysis of the genetics of the dancers vs. the non-dancers, Bush, Jiang, and Research Professor Yu Lan narrowed down the location of the gen...

Is that plant a tortoise or a hare? Answer predicts its response to environmental change

...one than pine. Soybeans, wheat and other crops are bred to grow fast, and they tend to be like poplars. This was an important predictor of how these trees and crops would respond to pollution. I wondered how they had come to have these traits in the first place and what the implications were for responses...

UNC researchers identify virus gene involved in tumor cell growth, spread

...ancerous. In addition, others have shown that mice bred to express this gene develop skin lesions. The UNC research shows for the first time how K1 does this in different cell types, Damania said. Kaposi's sarcoma is an angiogenic tumor, meaning that the tumor can recruit blood vessels to the tumor site,...

Sticklebacks reveal secrets to evolutionary change in Stanford study

...usand of miles away from the Vancouver fish. Marks bred the two freshwater sticklebacks and produced an aquarium full of fish lacking hind fins. Breeding the Icelandic sticklebacks to a four-finned saltwater fish once again generated offspring with hind fins. Together, these experiments suggest that the ...

Policy review in Science calls for Bush Administration to protect wild salmon

...ust populations existing in healthy habitats. Fish bred and fed in hatcheries are often larger than their wild cousins, grow quickly, and compete with them during early life stages in freshwater and estuaries. On release, hatchery fish can cannibalize their wild cousins and consume the food resources nece...

Study offers new model for breast cancer

...ncer cells used in these experiments typically are bred in Petri dishes and end up bearing little resemblance to human cancer. In addition, these tumor cells often stop growing after they've been injected. "Here, the human tumor cells grow because we've created a human environment, and that's a powerful...

Stress hormones and heart failure

...ceptor molecule called CRF2 on muscle cells. Mice bred specifically to lack the CRF2 receptor showed no r... blood pressure In addition, mice that were bred to exhibit a form of congestive heart failure were found to have a dramatic improvement in their car...

Unlocking the genetics and evolution of the dog could prove beneficial for humans

...ike terriers might dig up gardens because they are bred to go after rats and moles, researchers said. Karl Gordon Lark of the University of Utah discusses new findings on the regions of the dog genome, called genetic loci, which control one aspect of a dog's shape; while at the same time changing a diffe...

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