Tag: "broken" at biology news
Mysterious beach closures may be linked to contaminated groundwater, study finds
...om the restrooms or another source. ''If there's a broken
or leaky sewage pipe, we can flush dye down the toilets and see if it ends up in the groundwater,'' Paytan explained. The research team has begun similar groundwater-bacteria coupling studies at beaches in Singapore and Israel, and plans to expand it...
Drug combo effective in advanced breast cancer
...clinical trials. Targeted therapies attack what is broken
in a cell that makes it cancerous, resulting in fewer side effects than traditional therapies. Herceptin blocks a receptor on the surface of the cell that receives excess growth signals, interrupting the out-of-control growth that characterizes cance...
Penguins ingest mollusk shells to obtain calcium for thicker eggshells
...oft nesting material. Still, their eggs are rarely broken
because the shells are more than 50 percent thicke...entina. Just 257 of the eggs, or 2.6 percent, were broken
by anything other than predators or human-caused accidents, similar to the rate for birds that do no...
Archaeologists announce discoveries at the ancient Maya site of Waka' in northern Guatemala
...a have systematically reassembled the fragments of broken
stelae, and then copied them using latex molds to create fiberglass replicas. These efforts are part of a commitment not only to retrieve information from the remains of this once great city, but also to restore and rescue its ancient treasures. "We...
Kinase backgrounder: Iressa discovery part of major kinase project at Dana-Farber
... a sudden attack by a small, fast-moving force has broken
an impasse and helped turn the tide against an entrenched foe. In such situations, timing is everything. Dana-Farber researchers, sensing an opening in the cancer battle, are mounting a quick thrust to flush out suspected molecular cancer triggers in...
Genetic signature may predict recurrence in colon cancer patients
...hat cancer is not a homogeneous disease; it can be broken
down into still more categories or stages than are currently standard," adds Atkins. "The development of a prognostic assay to test for this genetic signature should allow physicians to better identify patients with a poorer prognosis and plan for m...
Inflammation, hypertension are focus of major new MCG research program
...t how the kidney controls its blood flow, why it's broken
in hypertension and whether or not we can make the case these agents are involved." Dr. Webb is looking at what role these agents or cytokines may play at the basic level of the smooth muscle cells that comprise blood vessel walls inside the kidney...
Rewriting textbooks on DNA crossover
... Meiosis includes a crucial step in which DNA is broken
and eitherrepaired by "crossing over" with another...r is made at a much earlier stage: afterthe DNA is broken
but before the ends of the breaks become stablyintertwined with their partner chromosome. Once the d...
New proteomics core at OHSU will speed discovery process
...pokes a hole in the gel." After the proteins are broken
down at the 2DiDx workstation, the "few dozen to few hundred" peptides are sent to the mass spectrometer. There, high-voltage electrostatic charges and a pump flowing at 200 billionths of a liter per minute blast the liquid samples through a needle-n...
St. Jude researchers create image of enzyme that orchestrates natural genetic engineering
...of one chromosome during replication and repair of broken
DNA by using a section of another chromosome as a ... of one strand of DNA as a blueprint to patch up a broken
section of another piece of DNA. This also contributes to introducing new genes into chromosomes. "T...
Carnegie Mellon U. develops microgel to recover enzymes for manufacturing, research assays
...sed an analogue of lactose that changes color when broken
down by the microgel enzyme. When the investigators added this substrate to the microgel, a yellow color instantly appeared, indicating the reaction's success. Once the reaction was complete, the temperature was lowered, causing the microgel particle...
Researchers caution against linking strep, neuropsychiatric disorders
... bit similar to arguing that drinking water causes broken
bones, since nearly everyone who has broken
a bone has drunk water or a water-based fluid the same day the fracture occurred. "It's human natur...
Pollution history documented through shell remains provides tool to study ecosystem change
...ether, external luster, edge preservation, and how broken
they were. "Wear could have been due to a change in stream gradient, but we found the most destruction was at the site of heaviest contamination and determined the heavy destruction was because there was no input of fresh-dead material," Brown s...
Awards honor Alt's three decades of genetic cancer research
...ong with the chromosome during cell division. The broken
ends join to broken
ends on other chromosomes, causing cancer-initiating translocations. As chromosomes keep breaking, ...
Gladstone study reveals how genetic factor may increase risk for Alzheimer's disease
...), include identifying where in the brain apoE4 is broken
down into toxic fragments that can impair the func...he current study relates to apoE4's tendency to be broken
down into toxic fragments when it is produced in neurons, the brain cells responsible for cognitive ...
New toxicity test could cut animal testing
...t seems benign in preliminary experiments could be broken
down in mammalian cells to produce a toxic product....
Study suggests possible way to repair damaged nerve cells
...ells. Normally, proNGF produced inside the cell is broken
down into two substances, one of which is mature NGF, a molecule that gets secreted to help neurons grow and survive. "But damage to mature neurons somehow blocks the normal production of helpful, mature NGF, and instead proNGF is secreted," Yoo...
Breast self examination increases women's concerns but has no effect on mortality
...e embargo because (1) the embargo has already been broken
and (2) it is a sensitive subject that needs to be handled with care to avoid misunderstanding among women. Hamburg, Germany: Breast self-examination (BSE) should not be seen as a cheaper alternative to mammography, and people who still advocate i...
JCI table of contents, March 1 2004
...****************************** Gene therapy for a broken
heart Despite significant ad-vances in the treatment of cardiac disease, chronic heart failure remains a leading cause of morbidity and mortality. Gene therapy represents a potential new strategy for the treatment of cardiac dysfunction. In the Marc...
Computer method identifies potentially active enzymes
... more different organisms. The variant enzymes are broken
and recombined with parts from the original enzymes creating the new one. "We have worked out ways to make libraries of novel enzymes by splicing proteins together," says Alexander R. Horswill, postdoctoral fellow in chemistry. "We wanted to know...
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