Researchers engineer mouse embryonic stem cells to form sperm cell precursors
... cells are limited to their given role. The study builds upon nearly a decade of research at the Whitehead Institute for Biomedical Research, Harvard University, and the National Science Foundation (NSF) Biotechnology Process Engineering Center (BPEC) at the Massachusetts Institute of Technology (MIT), all...Mercury in ocean fish may come from natural sources, not pollution
...orm it to a highly toxic form methylmercury that builds up in fish. Unfortunately, scientists are not yet able to measure methylmercury in ocean surface waters, so Morel and his coworkers approached the problem from a different angle. They measured methylmercury levels in yellowfin tuna caught off the...Research on spleen cells could yield potential cure for Type 1 diabetes
...th Research (SWHR) board of directors. The finding builds on a 2001 study conducted by Faustman and a team of MGH researchers in which a treatment that cures advanced type 1 diabetes in mice was discovered. In discovering the biological mechanism behind that accomplishment, the researchers also have opened...Genetic aberration helps explain variation in cystic fibrosis
... appear in both copies of the gene, a sticky mucus builds up in the lungs, making breathing difficult and trapping bacteria that can cause serious and deadly infections. One CFTR mutation, known as 5T, doesn't always cause CF even when 5T and one of the traditional CF-causing mutations are present, a per...New pathway found to enhance cancer treatment
...er 7 issue of the Journal of Biological Chemistry, builds on the prior DMS discovery that a potential retinoid receptor inhibitory protein called RIP140 is a byproduct of one of these target genes. Now the research team has found that RIP140 is responsible for repressing the retinoid receptors, adversely af...Study reveals patterns of gene activity in the mouse nervous system
...oteins, in the brain and spinal cord. The project builds on earlier efforts such as the Human Genome Project by helping investigators understand not only which genes are critical in the nervous system, but also what those genes do. All of the information from the project is publicly available to other res...Newly identified gene may halt fuzzy, moldy fruit
... concerns connected with their use. Also, Botrytis builds up genetic resistance to fungicides that are used frequently. "The most cost-effective and environmentally sound approach to preventing this disease is through genetic resistance. If we can use the same gene we found in Arabidopsis in other plants th...Better model of cancer development sheds light on potential angiogenesis target
...portant step in tumor angiogenesis, a process that builds blood vessels needed for tumor growth. In the earlier research on Id1, scientists used a mouse model in which tumor cells were injected directly into the animals to stimulate cancer growth: in effect, a tumor transplant. The tumors grew in the anim...NIH announces strategy to accelerate medical research progress
...ize its entire research portfolio. The NIH Roadmap builds on the tremendous progress in medical research achieved, in part, through the recent doubling of the NIH budget. In setting forth an ambitious vision for a more efficient and productive system of medical research, the NIH Roadmap focuses on the most ...NSF'S 'FIBR' to mix disciplines, use breakthroughs on 5-year explorations into biology's mysteries
...ence the genomes of their hosts. Another project builds upon recent discoveries from the vibrant, fuming thermal springs of Yellowstone. It will evaluate whether traditional species concepts apply to microorganisms or whether exchange of DNA in "horizontal," uninherited ways may require a new intellectua...Dana-Farber researchers to lead collaborative smallpox studies
...ce we determine the mechanism by which the vaccine builds immunity and, in some cases, produces complications, we'll be in a position to develop effective alternatives that carry fewer risks."...UC San Diego researchers receive $14 million from NSF for 10 new information technology projects
...ge Modeling. PI: Alon Orlitsky (ECE). This project builds on a new approach to the compression of strings over large alphabets. Orlitsky has already shown that patterns of strings drawn according to independent and identically distributed random variables can be compressed as if the distribution were known ...More than 700 threatened species remain completely unprotected, new study shows
... the vast majority of these species." The analysis builds upon the work of thousands of scientists and dozens of institutions around the world. Based on their work, CABS scientists compared a map of all protected areas for which reliable information was available to maps of more than 11,000 species ranges f...Northwestern's Cancer Genetics Program pinpoints gene that increases cancer risk by 26 percent
...lon cancers are caused by damage to the genes that builds up over a lifetime, but some people are born with a high risk of the disease," explains Pasche. "When inherited, the TGFRB1*6A gene makes people susceptible to having certain cells grow and divide uncontrollably, which may contribute to cancer devel...Brain patterns the same whether doing or just watching, Queens researcher discovers
... week in the current edition of Nature. The study builds on earlier findings by other researchers showing that some brain cells fire not only when picking up an object, but also when watching an experimenter do the same thing. Rather than mere imitation, Dr. Flanagan believed that such neural activity was ...$13 million grant boosts breast cancer research
...logy of proliferative breast disease. This project builds on Vanderbilt's historic strengths and will define the role of the transforming growth factor beta type II receptor and additional components of the TGF beta and EGFR signaling pathways in the development of pre-cancerous lesions of the breast. (Will...Anthrax research might provide more time for treatment
...reatment has no effect on the amount of toxin that builds up in the blood over time, however, making speedy treatment crucial. Standing in the Way of Infection "An effective anthrax inhibitor would be able to prevent the toxin from binding to receptors on the human cell, thereby hindering the toxin from ...Protein holds promise as new diabetes drug target
... work, reported in the July 18 issue of Science , builds on basic science performed at Vanderbilt University Medical Center that started 18 years ago. When Dr. Mark A. Magnuson arrived at Vanderbilt in 1985 as a postdoctoral fellow, he took on a challenging project cloning the gene for the enzyme glucokin...Sepsis drug fights infection, decreases hospital care over two year study
...ver 75 than for those younger than 65. The study builds on a previous study, the Protein C Worldwide Evaluation of Severe Sepsis (PROWESS), which ended in June 2000 when DAA (also known as activated protein C, or by its trade name Xigris) was approved by the Food and Drug Administration. In that study, 85...New science at K-State attracts $4.2 million from National Science Foundation
...laborations between scientific research teams, and builds the science infrastructure of a state so that it can become nationally competitive. Sources: Mike Herman, 785-532-6741; e-mail mherman@k-state.edu ; and Loretta Johnson, 785-532-6921; e-mail johnson@k-state.edu http://www.ksu.edu/ecogen News re...