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Key to Triplet Repeat Brain Diseases Open Door For New Way To Understand, Treat Genetic Diseases"

...said. Additional funding or support for the study came from the Joseph and KathleenBryan Alzheimer's Disease Research Center at Duke, the Duke Center for HumanGenetics, and the National Institutes of Health (specifically the NationalInstitute on Aging, and the National Institute of Neurological Disorders...

Tumor Suppressor Gene Located In Liver Cancer Cells

... of Zeneca are co-authors. Funding for the project came from the National Institutes of Health, Zeneca, the Proctor and Gamble Co. and MITRE Corp. "Liver cancer is one of the most common cancers worldwide, particularly because of its association with viral hepatitis," said Jirtle, a professor of radiatio...

Second Breast Cancer Gene Located

...ersity, Montreal. Funding for the project came from the Cancer Research Campaign, BREAKTHROUGHBreast Cancer Charity and the Jean Rook Appeal, the Institute of CancerResearch, the Wellcome Trust, the Medical Research Council, the ImperialCancer Research Fund, the U.S. Army, Duke University's Spec...

New Discovery About Genes Has Implications For Genetic Therapy

...owitz explained. "We wanted to know where introns came from and how they move. "This class of introns appears very primitive, as if they were the ancestors of introns found in higher organisms." Lambowitz believes that the introns are "parasites" on the genome, and behave similar to the way retrovi...

Enticed By A Chemical Tease, Female Beetles Are Rewarded With A Nuptial Gift To Protect The Next Generation

...sh fly aphrodisiac (although most of their beetles came from China and not Spain). The medical literature, while skirting the question of Spanish fly's efficacy as an aphrodisiac, does chronicle an unfortunate side effect for human males: "erections douloureuses et prolongues," in the words of a French F...

DNA Techniques Allow Scientists To Become Pollution Detectives.

...ldlife." Edmiston said knowing where the pollution came from could helpsave time and money spent devising solutions to protect theenvironment. "Down the road, these techniques could be used to help us manageour problems," Edmiston said. "There is good potential here tohelp us develop management plans for ...

Humble Pocket Gophers Shed Light On The Genetic Fortitude Of Cheetahs

... that seen in inbred laboratory mice. Key evidence came from a surprising 1985 experiment in which unrelated captive cheetahs accepted skin grafts from each other, a sign that their immune systems were genetically almost identical. However, in recent years some ecologists have questioned the validity of t...

A Genetic Skeleton Key

...erethe method did not give a perfectprediction, it came close, accuratelypredicting 94 to 97 percent. Even the lone case in which themethod seemed to fall down -- predictingwith 75 percent accuracy onthe basis of mouse data -- the failurewas interesting. In this case, chickendata for the same gene were al...

New Ultrasensitive Technique For Accurately Characterizing Biomolecules Is Developed By Cornell Chemists

...80.6 daltons. The breakthrough in sample reduction came about as a result of customizing very small quartz capillaries for electrospray. Valaskovic used laser heated fabrication, chemical etching and vaporized gold plating to produce capillary tips with a diameter of only one ten-thousandth of an inch (2...

Duke Primate Center Sets October Expedition To Find 'Juliet'

...ll search the jungle for the animals. Romeo first came to the Primate Center in fall 1993, along with his motherTitania and another unrelated male Oberon. The three animals were the firstdiademed sifakas ever brought into captivity outside Madagascar. Oberon arrived at the center in poor physical shape,...

Cholesterol Anchor Helps Signaling Proteins Direct Development

...ored to the surface of the cell that makes it. "It came as a complete surprise to discover that the cholesterol molecule helps cause the split and then serves as the anchor for the hedgehog signal," says Jeff Porter, Ph.D., a postdoctoral fellow and first author of the paper. "After spending two years sea...

Researchers Find How Disease-resistant Plants Recognize Bacteria

...t a defense mechanism to be. A piece to the puzzle came from medical science, where researchers found in the early 1990s that a bacterium, Yersinia pseudotuberculosis , infects cells not by invading the cell wall, but by introducing proteins directly into the host cell's cytoplasm. Scientists have given ...

Proteins Interacting With RNA And DNA Are Surprisingly Similar

...armethod tobind to RNA and DNA. Those similarities came as a surprisebecause theproteins have completely different functions, and they attach todifferentstructures -- the double-stranded, ladder-like DNA, and thesingle-strandedRNA. "You don't expect RNA-binding proteins to look like DNA-bindingproteinsbe...

Researchers Corral Millions Of Microscopic Membranes

...ford. Boxer got Ulman and Groves together and they came up with the idea of using microfabrication techniques to make smaller membrane corrals. "The hardest part was deciding what to do," Ulman said. The actual processing involved was straightforward. But, because electrical engineers have never thought a...

Duke University Students Devise Devices For The Disabled

...tudents in aDuke "Devices for the Disabled" course came to the rescue. The new course, taught by assistan...house and played around with him a little. Then we came back,revised our brainstorming, and decided on the sliding device." "One thing that made this proje...

Fund Aims To Repay Developing Nations For Valuable Genes

...cally for Ronald's Xa21 rice gene, whichoriginally came from rice plants found in the wilds of West Africa. Muchof the breeding work related to the location of the gene in the rice plantwas conducted at the International Rice Research Institute in the Philippines. According to the fund guidelines, any co...

Erodible plastic microspheres could be effective oral drug delivery system

...r undergraduates. Funding support for the research came from theNational Institute of General Medical Sciences in the National Institutes ofHealth....

NIH Team Discovers Endocrine Tumor Gene

...fort to analyze DNA from individuals with MEN1 who came from 15 different families. The researchers applied a powerful method of searching for mutations called dideoxy fingerprinting. If no mutations were found, a candidate gene was excluded. After testing and excluding 10 genes the big break came. Ou...

Scientists Trace Roots Of Protein That Keeps Antarctic Fish From Freezing

...y new being created. "The antifreeze glycoprotein came about differently, taking twoparts of its ancestor...t form the new protein," she said. "Thenew protein came from building from the ground up a very short sequencein the middle, and going through repeated dupl...

Teens Shop "Healthy", But Trust Label Claims Too Much

...olescent shoppers included in their study. Health came in second behind a category that included taste/personal preference, custom/habit and price/cost. However, the teens made their decision about what choices are "healthy" based on front-of-the-label claims rather than the actual nutrition informa...

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