Joslin researchers clarify mechanisms for beta-cell formation
... (insulin resistance). Poorly controlled diabetes can lead to a host of complications, including heart attacks, strokes, blindness, kidney failure, blood vessel damage and nerve damage. ...Wiley publishes Welcome to the Genome: A User's Guide to the Genetic Past, Present, and Future
...tery of the genome and how understanding its codes can better our lives. This fascinating book delves into the past discoveries that led to the sequencing of the human genome, presents genomics challenges facing today's scientists as well as society in general, and outlines future possibilities of the d...Folic acid vitamin use by women reaches all-time high, March of Dimes survey finds
...4. For results based on samples of this size, one can say with 95 percent confidence that the error attributable to sampling and other random effects could be plus or minus three percentage points. "Use of Vitamins Containing Folic Acid Among Women of Childbearing Age -- United States, 2004," by...JCI table of contents September 15, 2004
...ls are no longer defective -- this means the cells can complement one another. If the fused cells comple... Without PDX-1 Extra growth of pancreatic b cells can reduce the effects of insulin resistance. Loss of this compensatory increased growth, however, often...9/11 search-and-rescue dogs exhibit few effects from exposure to disaster sites
...e. "Since dogs age more rapidly than humans, they can serve as sentinels for human disease. We are enco...-rescue dogs and their handlers, we hope this data can be used to establish a baseline for future studies," Otto said. "Not only will it help ensure the h...New fruitfly model of diabetes has future implications for pancreatic cell transplantation
...human pancreas, Rulifson explains that now the fly can serve as a simple model of how sugar is regulated ... sense the nutrient and energy status of an animal can adjust an animal's growth and metabolic state," he says. "Now we have a model for that." Coaxin...Human chromosome 5 final sequence analysis released to public
...e information are data that the research community can trust and put to good use," said Richard M. Myers,...r prominence as researchers have learned that they can control the activity of distant genes. Some of the noncoding regions have also stayed remarkably con...Ecology of infectious diseases grants awarded
... how natural systems work, public health officials can recognize when an outbreak is unnatural. The recent outbreaks of West Nile Virus and SARS show how little is known about the ecology of infectious diseases. This year's EID awards include studies of the ecology, dynamics and spatial spread of raccoo...Venn diagram tactics to vet complex disease
...ls are no longer defective -- this means the cells can complement one another. If the fused cells complement each other, this means that the original cells had mutations in different genes. The authors then carry out a second round of fusions, but in these cells, they have had the mitochondrial DNA rem...Protein is key to fatal disorder and normal cell function
...mer's disease. Prions are infectious proteins that can transmit diseases such as Creutzfeld-Jacob or mad cow disease. Batten disease collectively refers to inherited disorders also called the neuronal ceroid lipofuscinoses, or NCL, which share similar clinical and pathological traits but are genetically ...Hardy buoys: Texas A&M project predicts oil spill movements
...ine - a system of buoys in the Gulf of Mexico that can accurately predict the movement of oil spills. Such spills can present Texas-sized problems, both environmentally and economically, to the state's coastline. The ...European common frog found to use novel mating strategy
...ermine the paternity of the fertilized eggs, which can number between 300 and 3,000 in this species, Vieites gathered 16 separate clutches and took tissue samples from the original parents and the pirates. With colleagues at the University of Konstanz, Germany, and the University of Amsterdam, The Nether...A liking for sweets, combined with novelty seeking, may predict alcoholism
...erimental Research indicate that alcoholic status can be predicted by a combination of two independent.... Then we tested the hypothesis that sweet liking can predict alcoholic status of an individual. Analysis showed that sweet liking by itself was not su...Peering inside the body, with a new spinliterally
...n technique inventor. "We think this new technique can be used to diagnose diseases and assess the body's...details is lost. Wind's slow-spin technique, which can generate detailed spectra from these boundary regions, takes advantage of a quirk in NMR. NMR genera...Genetically modified bacterium as remedy for intestinal diseases
... an advanced stage of such inflammations, patients can eat only via catheters. Crohn's disease has been ... acute and chronic intestinal inflammation, and it can potentially be extended to other therapeutics as well.......examined a receptor on CTL cells called NKG2D that can be activated by stress-induced chemicals and has b...ls that line the intestines of celiac patients and can be stimulated by wheat gluten, via IL15, in cells grown in the laboratory. By expressing MICA, the i...TANGO: towards faster prognosis of Alzheimer's and Parkinson's diseases?
..., have developed TANGO - a statistical method that can predict the susceptibility of proteins to sticking...are therefore difficult to purify. With TANGO, one can determine under what conditions the solubility of the therapeutic proteins is large enough to purify...First glimpse of DNA binding to viral enzyme
...st Walter Mangel, a co-author on the paper. "If we can block this interaction, we should be able to preve...virus (HIV), an opportunistic adenovirus infection can be deadly. During infection, adenovirus makes an enzyme called a protease, which cleaves or de...AACR applauds NCI initiative on nanotechnology
...gy in the fight against cancer. "Nanotechnology can serve as an effective complement to approaches inc...elemental level of biology. Such nanoscale objects can be useful by themselves or as part of larger devices containing multiple nanoscale objects. The new ......or the out-of-Appalachia theory, Mueller said. "We can infer only a North American origin," Mueller said.... at mutations in the mitochondrial DNA, biologists can infer the pattern of evolution. "What is happening now is that by focusing on mitochondrial genes an...