Study reveals first genetic step necessary for prostate cancer growth
...pen the door to new tests that predict whether the cancer will become aggressive and the development of trea... The gene is known to be defective in a variety of cancer types, including up to 60 percent of human prostate cancers. Rb is a member of a family of genes kno...New imaging technology at Joslin shown to detect early signs of type 1 diabetes
...n clinical trials to detect the spread of prostate cancer to the lymph nodes. "Given the known safety of magnetic nanoparticles in humans, the technology might someday be used in individuals who are genetically at risk for diabetes to detect this autoimmune process in its earliest stages," Dr. Benoist sugg...Cervical cancer is the second most common cancer among women worldwide. Research Human cancers generally develop through several steps -- initiation,...JCI table of contents: 1 September, 2004
... Zoledronic Acid Zings Cervical Cancer Cervical cancer is the second most common cancer among women worldwide. Research has shown that progression of the pre-malignant stages to invasive c...Analysis of gene expression in lymphoid cells can determine lymphoma cancer
...t. Non-Hodgkins lymphoma is the sixth-most common cancer in the United States. "Basically, this new method... very powerful tool in determining the presence of cancer by analyzing these two molecules in the lymphoid tissue," explains Giordano, an internationally reco...Anti-cancer compound in vegetables found to block late-stage breast-cancer cell growth
...chemical sulforaphane can block late stages of the cancer process by disrupting components of the cell calle...y. Singletary, a researcher in phytochemicals and cancer chemoprevention, and Jackson exposed cultures of malignant human breast cancer cells to SUL. Within...Protein involved in childhood disorder linked to cancer
...er also plays a role in DNA damage repair and thus cancer prevention. The research appears as the "Paper ...alin function to DNA damage responses that prevent cancer from developing," said David F. Stern, Ph.D., and Xingzhi Xu, M.D./Ph.D. of the Yale University Scho...Green tea research leads to gum and other products
...ons that drink green tea regularly have much lower cancer rates than populations that don't. His research he...he behavior of healthy cells as polyphenols target cancer cells for destruction. This change of behavior protects the healthy cells. Dr. Hsu discovered that t...Other highlights in the September 1 JNCI
...rupts a stress-related pathway in glucose-deprived cancer cells and inhibits tumor growth in mice, according to a new study. Tumors can become glucose- and oxygen-deprived when they lack blood vessels, which transport these molecules. Cells deprived of glucose accumulate unfolded proteins, but such cells ...How an insidious mutation fools DNA replication
... how a flaw in DNA that is central to mutations in cancer and aging fools the cellular enzyme that copies DN...hinery that can trigger the uncontrolled growth of cancer or the death of cells in aging. However, researchers have long known that the 8-oxoguanine-adenine m...Humans march to a faster genetic 'drummer' than primates, UC Riverside research says
... Sometimes the mutations result in the growth of a cancer tumor, or some other genetic defect. The team, which also included Rosaleen Gibbons, Lars J. Dugaiczyk, Thomas Girke, Brian Duistermars and Rita Zielinski, identified over 2,200 new human specific Alu DNA repeats that are absent from the chimpanzee ...Probing the surface of white blood cells to enhance immune system medicine
...heumatoid arthritis and lupus, as well as AIDS and cancer metastasis. The researchers, led by Henry N. Hig... suppression for transplant recipients. Since many cancer cells share the same mechanism of extravasation as lymphocytes, ablating microvilli could also preve...MIT team explains yin-yang of ginseng
... "He had the foresight to integrate the biology of cancer and blood-vessel formation to the pharmacological behavior of this drug and its structure." MIT's role in the collaboration grew from Sasisekharan's expertise in complex sugars, which turn out to be key to ginseng's activity. "The sites where sugars ...Advances in tumor angiogenesis Dendritic cells co-opted to the dark side
...ania School of Medicine discovered that in ovarian cancer immune cells can change into blood-vessel cells, a...ere initially observed in a mouse model of ovarian cancer that the investigators generated and then confirmed in human ovarian cancer. This work may lead to n...University of Pittsburgh receives $10 million grant for head and neck cancer
...PORE awarded to UPCI the first was awarded to the cancer institute's Lung Cancer Program in 2001 and is one of only four SPORE grants in head and neck cancer awarded nationally. "Head and neck cancer is one of the most physically and emotionally debilitating...Bright idea could doom cancer and viruses, say Purdue scientists
...ong made use of platinum-based compounds to poison cancer cells. These compounds bind DNA in the cellular nu...lls in the body in the process. "That's the reason cancer patients often lose their hair," Morrison said. "Hair cells, like many others in the patient's body,...Tiny molecules have big potential as cancer drugs, Stanford researcher believes
PHILADELPHIA Many cancer therapies take a "big stick" approach, targeting r...ints toward the possibility of a different type of cancer drug small molecules that would home in on the proteins tumors need without poisoning patients. Mat...Trojan Horses, xenon imaging and remote controlled genes
...nd the capabilities of MRI for monitoring multiple cancer markers simultaneously using the noble gas xenon a...he cage. When the cage is "rattled" by a specific cancer protein, for example, the xenon molecule will emit a telltale signal that can be tracked by MRI. "B...Light turns on anticancer agents
...issue while aggressively treating diseases such as cancer with powerful medicine, scientists have been creating therapy agents that they can activate with light only at the site of a tumor. Until now, almost all photodynamic therapy agents have required oxygen. Yet, tumors are often oxygen depleted. Now, V...Synthesized molecules studied as weapon to stop cell division in cancer cells
...on, is present at high levels in a wide variety of cancer cells. Virginia Tech researchers who are designing...s programmed cell death -- which is good if it's a cancer cell. "It makes sense to inhibit the Pin1 enzyme," said Etzkorn. Protein shape determines biologic...