Anticancer drug zebularine specifically targets tumor cells
...iting cell growth and promoting gene expression in cancer cells, notes Peter Jones, Ph.D., director of the U... of zebularine's effect on the rate of division of cancer cells, Jones and colleagues showed that zebularine slows growth by as much as 68 percent in cancer c...2nd media alert First Scientific Conference on Childhood Leukaemia
... survivors face higher risks of developing another cancer or other serious health problems. This has brought a new urgency to the need for research to establish whether the disease is potentially preventable. As well as presenting new findings in areas where research has already indicated possible associat...Researchers find clues about how antibodies specialize
...rong regions, potentially leading to activation of cancer genes. "Now that we've learned how AID gets ac..., these two lines of investigation--immunology and cancer -- have intersected and informed each other....New compound could give some types of cancer the one-two punch
...earchers are working on developing a multi-purpose cancer drug that might one day scale back the number of medications some cancer patients need to take. In laboratory tests, a dual-action compound called OSU 111 has shown promise ...Livermore research in accelerator mass spectrometry highlighted at ACS meeting
... cooking of meat and research on the prevention of cancer due to those chemicals. Her talk also will be incl...rkers for atherosclerosis, DNA oxidation in breast cancer cells, pharmacokinetics and development of novel drug delivery devices. Henderson will present an ov...Illustrated guidebook published for Chinese biomedical scientists and students
...g Harbor Laboratory, the world-renowned center for cancer and genetics research in Long Island, New York, has benefited greatly from this influx of talented Chinese students and postdoctoral fellows. Now Cold Spring Harbor Laboratory Press has published a book and a talking website intended to build confide...Study suggests cell-cycle triggers might be cancer drug targets
... proteins, when overly active, have been linked to cancer cell proliferation. With one significant exception...y if this would create problems for an anti-cyclin cancer therapy in patients. "It's not known whether D cyclins are required for blood cell generation in adu...Sweet success in targeting sugar molecules to cells in living animals
...with other cells. "Glycobiologists have known that cancer cells, for example, exhibit changes in glycosylation patterns when compared with their normal healthy tissue counterparts," said Bertozzi. "And there are changes in glycosylation of blood vessels at sites of chronic inflammation that are characterist...When is a mouse like a test tube?
...d are produced abundantly by inflamed cells and by cancer cells, which means her technique could be used to ...going a change in metabolism, such as happens with cancer cells and inflamed cells that over-produce sialic acid. The technique opens the door to non-invasive...Study narrows search for genes placing men at increased risk for prostate cancer
...from the largest study of the genetics of prostate cancer undertaken to date. Results have zeroed in on thre...en more vulnerable to this common cancer. Prostate cancer is the second-leading cause of cancer death in US men. The findings appear in the August 18 issue of...Other highlights in the August 18 JNCI
...mosomal regions that are likely to harbor prostate cancer susceptibility genes. Prostate cancer is the second leading cause of cancer death among men in the United States. Family history is one of...New mechanism for display of foreign proteins to immune system
...ce of virus infected cells and abnormal cells like cancer cells. The findings provide new insight into how the immune system identifies potentially harmful cells and may be exploited for future development of more effective vaccines. It is well established that the immune system has sentinel cells whose job...Tips from the journals of the American Society for Microbiology
...accine that targets proteins expressed in cervical cancer cells. Their findings appear in the August 2004 i...virus (HPV) is found in more than 99 % of cervical cancer cases, which is the second leading cause of cancer death among women throughout the world. Consiste...Progress in breast cancer progression
Breast cancer is the most common cancer among women and the second leading cause of cancer death among women. The prognosis for cancer pati...JCI table of contents, 16 August, 2004
... Progress in Breast Cancer Progression Breast cancer is the most common cancer among women and the second leading cause of cancer death among women. The prognosis for cancer pati...MICs shed light on prostate cancer
...The researchers found that MIC-expressing prostate cancer cell lines were able to activate natural killer ce...ces, and that this was the means by which prostate cancer cells could overcome this particular form of immune surveillance. The deficiency in the ability to a...Hopkins scientists use blood proteins to detect ovarian cancer
...chers have designed a blood test to detect ovarian cancer using three proteins found in common in the blood ...ein patterns present in blood samples from ovarian cancer patients at several U.S. and international hospitals. Other research groups are evaluating ovarian ...Protective gene may enhance vaccine responses
...ases that have previously eluded vaccines, such as cancer or AIDS. When the immune system detects an invader, such as a virus, T cells with an affinity for that particular invader multiply rapidly, attack and eliminate infected cells. Once the infection is cleared, however, 90 to 95 percent of those T cell...Ovarian cancer sheds tumor suppression with loss of estrogen receptor
...anti-estrogen drugs including Tamoxifen. "Ovarian cancer is remarkably lacking in response to antiestrogens...sion of message for ER beta in tumors from ovarian cancer patients." Tumors from 58 ovarian cancer patients contained less messenger RNA for the ER beta than ...Jefferson Lab detector technology aids development of cystic fibrosis therapy
...dy proved its usefulness, for instance, in imaging cancer tumors. According to Jefferson Lab's principal investigator on this project, Drew Weisenberger, the team has designed and built several small animal imagers for use in biomedical research. "Researchers use animals all the time in developing i...