Tag: "cancer" at biology news
Patients' cells from tumors, the immune system merged for customized cancer therapy
One of the strongest natural allies that cancer
patients can tap to help fight tumor growth and me...rch team documented tumor regression in two breast cancer
patients, and stabilization and containment of tumor growth in late stage breast and kidney patients...
Gene expression patterns may help predict risk and progression of prostate cancer
...es expressed in benign tissue adjacent to prostate cancer
tissue are much more similar to those expressed in prostate cancer
tissue than previously thought. This finding, the first of its kind, may help predict populations bo...
Scientists identify molecular link driving spread of skin cancer
...eraction, significantly deterring the migration of cancer
cells beyond the original tumor site. Blocking thi...s described in their study, the spread of melanoma cancer
cells requires the interaction of two proteins, one located on the cell's surface called CD44, and a...
New drug shows promise against Gleevec resistance in mice
..., who in addition to being a researcher, also sees cancer
patients at UCLA, has long been hunting for an exp...-Myers Squibb and BMS-354825's reincarnation as a cancer
drug was under way. As Sawyers is quick to point out, only time and further research will ...
Rutgers chemist uses NMR to elucidate protein-DNA interaction
...re-dispose individuals to harmful diseases such as cancer
and Alzheimer's disease. Through the use of the nuclear magnetic resonance (NMR) spectroscopy, Kalodimos and his co-workers were able to determine how proteins slide along the lengthy strands forming the helix structure of DNA until they rea...
Protective mechanism exploited by tumors may provide new cancer treatment
...ignificantly closer to using this approach to help cancer
patients. "We have demonstrated that the IDO inhibitor drug is useful in mice," says Dr. Munn. "It's useful in a tumor model that is related to the kinds of patients we would want to treat. This brings us closer to being able to approach the FDA sugg...
European researchers tackle mitosis
...on of mitotic genes, and to test them as tools for cancer
diagnosis. All data produced through MitoCheck will be readily available to the scientific community and the public through databases at the DKFZ, and at The Wellcome Trust Sanger Institute, another MitoCheck partner. "This project is an excellent ...
Findings suggest need for new view of p53 cancer protein's interaction with DNA
...e journal Structure. "Mutant forms of p53 in human cancer
are often defective in their binding to DNA, and a...roups are trying to develop drugs that might treat cancer
by restoring the DNA-binding activity of these mutants," says Thanos D. Halazonetis, D.D.S., Ph.D., ...
Gene profiles could improve acute leukemia diagnosis and lead to better treatments
...al, is published in the journal Blood . AML is a cancer
that arises in bone marrow hematopoietic stem cells (HSCs) or progenitor cells that are destined to become myeloid cells (cells normally committed to fighting infections). Gene microarray technology uses small chips containing gene "probes" to measur...
Warren Pharmaceuticals publishes results of preclinical evaluation
...marketed for the treatment of anemia. Millions of cancer
patients and those in kidney failure have received EPO for treatment of low blood count, generating over $9 billion in annual worldwide sales. This compound has attracted special interest recently because of its newly discovered role in protecting t...
Access to DNA secrets yields better understanding of genes, possible tool for disease diagnosis
...am will apply various drugs such as those used in cancer
therapy to cells in order to understand if and ho...action and expansion states might be indicative of cancer
or other diseases. "Our current study describes the platform technology necessary to try to understa...
Structure solved at Scripps shows how one human protein reduces potency of chemotherapy
... drugs and resistant proteins [intended to improve cancer
therapies]," says Tainer. Cancer, Chemotherapy, ...For years, one of the best available ways to treat cancer
has been through the administration of chemotherapy drugs, such as "alkylating" agents, which inhibi...
Anti-cancer agent built from anti-inflammatory drug
...ti-cancer agent. The new agent works by triggering cancer
cells to self-destruct. The agent is now undergoi...rks by inhibiting a fundamental signaling point in cancer
cells, making it potentially effective in a wide range of cancer
types," says study leader Ching-Shi...
Animal research suggests plant estrogens in soy do not increase breast cancer risk
...oy does not increase the risk of breast or uterine cancer
in postmenopausal women. "This is convincing evid...do not stimulate cell growth and other markers for cancer
risk," said Charles E. Wood, D.V.M., lead researcher, from Wake Forest University Baptist Medical Ce...
Study supports association between HPV infection and head and neck cancer
...from a trial of an HPV vaccine to prevent cervical cancer
raises hope that such a strategy can also be used to reduce the incidence of HNSCC."...
Milk consumption and calcium intake associated with lower colorectal cancer risk
...rnal of the National Cancer Institute . Colorectal cancer
is the third most common cancer
worldwide. Researchers have hypothesized that the different rates of colorectal cancer
incidence in ...
Other highlights in the July 7 JNCI
...ugh surgery, which is only be performed before the cancer
has metastasized clinically, as the cancer
does not respond to standard chemotherapy or radiation. Cinzia Lanzi, Ph.D., of the Istituto Nazion...
Croatian skeletons reveal changing status of cancer in Europe across the centuries
...our recent ancestors, reinforcing the concept that cancer
is a 'modern' disease and is largely a consequence...rs most clearly correlated with the development of cancer
in the European Union are smoking (estimated to cause 30% of all cancer
deaths) and obesity / dietar...
UCSD team determines cellular stress within body is critical
...ne disorders, transplant rejections, and potential cancer
therapies. Published in the online edition of the ... excited about the implications of our findings to cancer
cell biology," Ho said. "The tissue microenvironment of tumors is unique because the unregulated gro...
Chemoradioimmunotherapy for advanced breast cancer: hope for the future?
...ul, and novel, technique to kill metastatic breast cancer
cells by circumventing their chemo- and radioresis...reasons for this poor prognosis is that metastatic cancer
cells are less responsive to treatment than primary tumour cells. This is partly caused by the fact ...
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