Tag: "cancers" at biology news

Other highlights in the March 3 issue of JNCI

...re nevertheless at an increased risk of epithelial cancers such as cancer of the esophagus, stomach, colon, l...life among retinoblastoma survivors--specifically, cancers that are likely not related to radiotherapy. Olivia Fletcher and Julian Peto, of the London School o...

New imaging technique developed to identify breast cancer

...onance Imaging. Scientists have long known that cancers contain elevated levels of choline, a product of membrane synthesis, but the Hopkins study is believed to be the first to demonstrate its value in accurately identifying breast tumors. MRSI of the breast does not appear likely to be cost-effective a...

Teens and young adults the new frontier in cancer says US cancer specialist

...ess. One important factor was that the spectrum of cancers among adolescents and young adults is different from any other age. "There is no discipline in medicine devoted to this group. Neither paediatric oncologists nor oncologists who are for adults are trained certainly not optimally for this set of dis...

Cancer rates in teens and early 20s rising

...to an average increase of 1.2% per year. Different cancers dominated at different ages. Among 13 and14-year-o... She said that the increasing incidence of certain cancers over time would be consistent with environmental (exogenous) risk factors, which are becoming more f...

Drugs limit deadly side effects of graft-versus-host disease

...ld mean to patients with blood- and marrow-related cancers who need a transplant, but have a high risk of developing graft-versus-host disease," Ferrara says. "Only about 25 percent of BMT patients have a perfectly-matched sibling donor, so this is good news for the other 75 percent." Ferrara adds that he ha...

St. Jude/Mayo Clinic study finds direct link between CBP gene and lymphoma

...a narrow set of dysregulated genes." Lymphomas are cancers of either B-lymphocytes, which produce antibodies, or T-lymphocytes, a group of cells that either stimulate B cells or orchestrate attacks on cancer cells or invading organisms. In this study, loss of CBP only led to T-cell lymphoma. Another unexpect...

Double mastectomies significantly lower risk of breast cancer in women who are genetically at risk

...eight. Between three and 10 percent of breast cancers may be related to mutations in the genes BRCA1 and BRCA2. Women can inherit these mutations from their parents, and it may be worth testing for either mutation if a woman has a particularly strong family history of breast cancer. If a woman is foun...

Protein abundant in human tumors confers resistance to anticancer drugs

...of the biology underlying drug action and why some cancers are drug resistant are not well understood. A research team led by Dr. Donald Kufe from the Dana-Farber Cancer Institute in Boston, Massachusetts examined the role of a protein called MUC1 in drug resistance in cancer cells. The level of MUC1 is subs...

UCSF finding advances insight into adult stem cells in human brain

...ought to be derived from astrocytes. Because these cancers generally are not detected until they are advanced, when symptoms have begun to develop, scientists do not know where - or what - initiates the process of uncontrolled cell replication that leads to the formation of these brain tumors. Some evidence ...

Revised guidelines published for testing for hereditary type of colorectal cancer

...r than age 45 and can result in the development of cancers in a variety of tissues, such as the colon, rectum...acteristics that put them at an increased risk for cancers associated with a particular mutation. In 1997, a panel of experts created the Bethesda Guidelines, ...

Equine cloning's triple play sheds light on calcium, cell signaling, human disease

... light-colored horses to develop melanomas or skin cancers that do not metastasize. Woods found the veterinary literature was devoid of a report of a stallion with prostate cancer.The cancer mortality rate for horses is approximately 8 percent for horses and 24 percent for humans, he said. Blood samples from...

Advances in equine cloning may aid insight into human diseases

...greater insight into human diseases. As some human cancers and age-onset diseases develop, calcium concentrations escalate in cells. The mule cloning demonstrated that equine cell activation and division rates can be accelerated by exposure to calcium, "suggesting the use of equines as valuable animal models...

Copper may play role in 'starving' cancer to standstill

...er one year," Harris noted. "And it was found that cancers of the muscle don't respond to this treatment. But...ers a place to look to see what is different about cancers of the muscle and blood vessel supplies." Harris said every drug ever made has been tested against ...

New hereditary cancer mutation found -- arrived with a German immigrant almost three centuries ago

...sible for a sizeable portion of certain hereditary cancers in Americans. People with this mutation are at hi...ps they can take to protect themselves against the cancers associated with the syndrome," says Stephanie M. Coronel, genetic research associate at Creighton Me...

Imaging technique discovered at Stanford monitors cancer cell proliferation

...oo slowly. Accelerated cell division can result in cancers that proliferate rapidly unless anti-cancer agents intervene. To measure cell division timing, the researchers incorporated fluorescent proteins, called biosensors, into the cell nuclei. When used with a specialized microscopy technique called total ...

Research points in new direction for cancer clues

...ment of precancerous prostate lesions and invasive cancers in the forestomachs of mice bred to eliminate a particular cell signaling pathway only in fibroblasts. These fibroblasts are supporting cells adjacent to the epithelial cells. "The key finding is that we were able to show that a signaling pathway i...

Algorithms help diagnose cancer

...t's possible that Q5 may be used to test for other cancers and diseases." The researchers explain that there is much still to be learned from the different types of information within a sample of blood, and Q5 is one means of extracting new and important data. "Most exciting to us, unlike previous mass spec ...

Inflammation marker predicts colon cancer

... per liter) were more likely to develop colorectal cancers than those with low levels of CRP (a median of 1.9...o found that: The odds of developing colorectal cancers increased progressively with higher concentrations of CRP. Overall, people in the highest fourth of ...

Other highlights in the February 4 issue of JNCI

...he incidence of ER-positive and ER-negative breast cancers with age and postmenopausal hormone use, and of PR-positive and PR-negative breast cancers with reproductive history and body mass index after menopause. The authors concluded that incidence ...

New mode of action discovered for tamoxifen

...cells, which have lost the gene expression, causes cancers to be less invasive. The UI study showed that treatment with tamoxifen turned maspin expression back on in breast cancer cells that had lost the gene expression. The study suggests that one of tamoxifen's beneficial effects is due to its ability to t...

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