New insight into diet and colon cancer
... on rats, which were injected with azoxymethane, a carcinogen known to induce colon cancer, and then the scienti... the crypts," Morris says. "Presumably, after the carcinogen is metabolized in the liver, it goes through the bloodstream. There may be more blood vessels in the...T cells can halt development of skin cancer, Yale researchers find
...o the skin; a systemwhere a single potent chemical carcinogen (methylcholanthrene) is injected into the skin; and a system where chemical carcinogens are serially painted onto the skin. Girardi said this last model most closely emulates cancer development in human skin and other organs because it mimics the rep...Black raspberries show multiple defenses in thwarting cancer
...injected with NMBA, a chemical carcinogen that induces esophageal cancer. NMBA is one of a group of chemicals called nitrosamines, compounds that have been linked to cancer. Nitrosamines are found in fried bacon, cured meats, tobacc...Exposure to toxin in certain foods could cause testicular cancer
... M.P.H., Ph.D., proposes that exposure to a common carcinogen called ochratoxin A during childhood or even before birth may set up the testes so that testicular growth during puberty triggers the launch of testicular cancer. Ochratoxin A results from molds that grow in grains and coffee beans and is found in a...New technique monitors chromium contamination in groundwater
...electroplating, hexavalent chromium is a suspected carcinogen and a common contaminant in groundwater. Now, scientists have discovered a simple, but effective, method for monitoring this pollutant. Under certain chemical conditions, hexavalent chromium will convert to trivalent chromium a less toxic form whic...Black raspberries a potentially powerful agent in fight against colon cancer
... Rats were injected with azoxymethane (AOM), a carcinogen that causes colon tumors. Afte.... Every rat injected with the carcinogen AOM developed the ACF lesions. While most of these lesions go away on their own,...New research supports the link between cooking and carcinogens
... acrylamide levels in foods suggests the suspected carcinogen forms in dangerous levels during the cooking of potatoes. The findings are reported in the August 14 print issue of Journal of Agricultural and Food Chemistry, a peer-reviewed journal of the American Chemical Society, the world's largest scientific...Maternal alcohol use during pregnancy may increase offsprings breast cancer risk
...ale offspring reached adulthood, they were given a carcinogen to initiate mammary cancer. Results of the study showed that offspring who were exposed to a moderate or high dose of alcohol in utero experienced a significantly higher number of breast tumors when compared to controls. While no human studies are ...Food expert says more tests needed before fried foods are tabled
... the month to discuss the discovery of a potential carcinogen in starchy, fried foods. "An ad hoc group, compos...n. Acrylamide is considered to be a probable human carcinogen and is a known neurotoxicant, said Joanne Lasrado, doctoral candidate in foods and nutrition at Purd...Study sheds light on how the sun causes skin cancer
... the Rb pathway were the cell's main environmental carcinogen sensor, she added. Turning the findings into a tool for diagnosing human melanomas will require more basic research. "People have not thought to correlate Rb status with sun exposure history and progression of pigmented lesions," Chin said. "It is no...Engineered proteins will lead to 'synthetic biology'
...nce. -- TNT, which is a nonbiological compound and carcinogen that the Navy is seeking to detect, as part of developing a TNT-sensing robot to aid its environmental cleanup effort. -- lactate, which is an indicator of metabolic stress in the body and also associated with certain cancers. Thus, a lactate-sensing...New target for skin cancer confirmed
... two months old, the scientists applied a chemical carcinogen to the skin of their backs, followed by five-times-a-week exposure to UVB light, the ultraviolet light that causes skin cancer. At 31 weeks of age, a much smaller percentage of JNK2-deficient mice had tumors (18 percent), compared to control mice (48...DFG presents the new MAK and BAT Value List 2003
...gned to carcinogenicity category 3B as a suspected carcinogen and the previous MAK value was suspended because of genetoxic activity. The commission recommends setting a much lower threshold value for industrial safety than the 5 ppm that have applied so far. In the course of examining suspected carcinogens in ...Better model of cancer development sheds light on potential angiogenesis target
...1 plays in angiogenesis." In the model using skin carcinogen exposure, the team's preliminary findings suggest that cancers may develop faster in mice without Id1 because inactivation of the Id1 gene triggers alterations in a receptor on skin immune cells called gamma delta T cells. With a faulty receptor, th...Lycopene's anti-cancer effect linked to other tomato components
...ois randomly assigned 194 male rats treated with a carcinogen to induce prostate cancer to diets containing whole tomato powder, pure lycopene or a control. Four weeks later, the rats were divided into two groups, with one having unlimited access to food and the second consuming 80 percent of the first's averag...Can a plant that acts like poison ivy cure prostate cancer?
...ory animals following the introduction of a strong carcinogen at a low dose. Subsequent laboratory tests, however, produced dramatically different outcomes. "It turned out that extremely low concentrations of TPA had an extraordinarily potent effect on myeloid leukemia cells, causing them to rev...Research finds lawn chemicals raise cancer risk in Scottish terriers
...ickman because they require far less exposure to a carcinogen than other breeds before contracting the disease. "You might compare them to the canaries used in coal mines a century ago," he said. "The difference is that we don't deliberately place our research animals in harm's way. We study animals that have a...Molecular image of genotoxin reveals how bacteria damage human DNA
...standing how the toxin damages DNA. "CDT may be a carcinogen because it damages DNA," says Stebbins, assistant professor and head of the Laboratory of Structural Microbiology at Rockefeller. "That makes CDT interesting in terms of both infectious disease and cancer." While normal cells regularly replicate, or ...