Tag: "cardiomyopathy" at biology news

Researchers identify second gene responsible for rare syndrome associated with skeletal defects

...amilial partial lipodystrophy, muscular dystrophy, cardiomyopathy and a premature aging disorder called progeria. "It is likely that minor changes in these genes may predispose individuals to premature aging, a change of body-fat distribution, as well as osteoporosis," said Dr. Garg. The researchers studied six...

JCI Table of Contents

...ted that while patients with familial hypertrophic cardiomyopathy due to cardiac troponin T (cTnT) mutations often suffer sudden cardiac death, they do not develop significant ventricular hypertrophy (ventricle enlargement), suggesting that a distinct cellular mechanism apart from alterations in myocardial contract...

Old drug works new tricks for iron overload heart disease

...large percentage of those patients end up dying of cardiomyopathy (disease of the heart), which is now reaching epidemic levels worldwide." Oral medications like calcium channel blockers amlodipine, verapamil and diltiazem were tested on mice with iron overload cardiomyopathy. "This surprisingly simple and effectiv...

JCI table of contents, February 2, 2004

... in nuclear structure and function promote dilated cardiomyopathy in lamin A/Cdeficient mice AUTHOR CONTACT: Diane Fatkin Victor Chang Cardiac Research Institute, Darlinghurst, Australia. Phone: 61-2-9295-8518 Fax: 61-2-9295-8501 E-mail: d.fatkin@victorchang.unsw.edu.au View the PDF of this article at: https://...

JCI table of contents, March 1 2004

...*** Understanding the cause of vascular spasm and cardiomyopathy Evidence suggests that mutations in diverse compo...onclude that, in contrast to previous suggestions, cardiomyopathy and associated vascular spasm in delta-sarcoglycanknockout mice arises from a primary requirement fo...

JCI table of contents, 17 May 2004

...autoimmune attack as a cause of idiopathic dilated cardiomyopathy AUTHOR CONTACT: Roland Jahns, University of Wuerzburg, Wuerzburg, Germany. Phone: 49-931-201-70460; Fax: 49-931-201-70730; E-mail: jahns@wpxx.02.toxi.uni-wuerzburg.de View the PDF of this article at: https://www.the-jci.org/press/20149.pdf ACCOM...

Strengthening independent junior research groups in collaborative research centres

...t 500,000 patients in Germany suffer from dilative cardiomyopathy the disease that is the major indication for hear...gional Collaborative Research Centre "Inflammatory cardiomyopathy molecular pathogenesis and therapy" attempts to bridge the gap between basic research and potential...

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