DNA unzipping found to take at least two proteins, not one alone
... to genetic diseases such as Bloom syndrome, which carries an increased risk of cancer, and Werner syndrome (premature aging). Viruses, including the hepatitis C virus, import their own form of these proteins to infect their hosts. Helicases separate strands of DNA. They travel along DNA highways, powered ...Kurt Wthrich of The Scripps Research Institute wins 2002 Nobel Prize in Chemistry
...erred the greatest benefit on mankind." Each prize carries a cash award of roughly one million dollars. Last year, K. Barry Sharpless, Ph.D., W.M. Keck Professor of Chemistry at TSRI and member of TSRI's Skaggs Institute for Chemical Biology, was awarded the 2001 Nobel Prize in Chemistry for the development ...Salk Institute professor Sydney Brenner receives 2002 Nobel Prize for medicine
... Nobel who established the awards-in Stockholm. It carries a cash award of about $1.1 million, which will be shared equally among the three scientists. Sharing this year's prize with Brenner are John E. Sulston from the United Kingdom and H. Robert Horvitz from the United States. Horvitz, 55, is at the Massa...Sequenced malaria genome exposes novel drug targets
...our a relict chloroplast, the part of a plant that carries out photosynthesis. Scientists have determined this relict, called the apicoplast, is essential for the malaria parasite's survival, but its exact role is unclear. McFadden's team has gone someway to unraveling the apicoplast's mysteries. They hav...Scientists decipher genetic code of malaria parasite
...squito Anopheles gambiae the insect "vector" that carries the deadly form of human malaria. TIGR researchers contributed to that sequencing effort which was led by Rockville-based Celera Genomics Corp.-- by producing about 40,000 BAC end sequences (large fragments of DNA), which were essential to the asse...Researchers discover new risk factor for colon cancer
...thnic group in which one percent of the population carries the gene mutation that causes Bloom syndrome. A collaborative team of investigators from Memorial Sloan-Kettering Cancer Center, the University of Michigan, and the Technion Faculty of Medicine in Haifa, Israel, studied 1,224 Ashkenazi Jews who devel...Breast cancer gene repairs damaged DNA
...fact that it is often mutated in tumors -- that it carries out an important function in homologous-recombination-mediated repair," said Pavletich. Producing this large protein fragment of BRCA2 and crystallizing it for x-ray crystallographic studies was a formidable challenge. Lead author Haijuan Yang got a...New possibilities for deadly childhood brain cancer
...cells taken from human patients. The Hedgehog gene carries the blueprint for the crucial signaling protein that tells other cells what to become during an embryo's development. If this signal is turned on later in life, Hedgehog can lead to cancer, especially in the cerebellum where medulloblastomas arise, s...Awards of the Netherlands greatest prize for science
...highest Dutch prize for scientific achievement and carries a grant of EUR 1.5 million per recipient, to be sp...terface between optics and solid state physics. He carries out research into how light beams travel through materials, and especially those materials which mak...Of mice and men: Deaf mouse leads scientists to new human hearing loss gene
...eam are working to develop a transgenic mouse that carries a normal Tmie gene, so they can test approaches for turning the gene on and off. They also hope to build a virus-based "vector" that will allow them to insert a normal Tmie gene into mice that carry a mutated version of the gene, in an attempt to cor...New insight into how eyes become wired to the brain discovered by Salk, UT Southwestern scientists
...rry signals from the nerve cells, much like a cord carries electricity to a lamp. During eye development, axons grow from different parts of the retina and out the back of the eye, forming the optic nerve. The optic axons grow from four distinct parts of the retina left-right and top-bottom and terminate ...Noggin mutation causes rare congenital hearing loss
...nce of being born with the syndrome, if one parent carries the mutation. Comparing DNA from nine members of one family and three members of another family with closely related symptoms, U-M researchers found similar mutations in a gene called NOG. NOG holds genetic instructions for the production of noggin -...New research supports the link between cooking and carcinogens
...ist is hesitant to promote mild cooking because it carries its own set of dangers -- namely food-borne diseases like Salmonella. Still, she said, the data support the conclusion that consumers should avoid overcooking, especially with potatoes. "It should also be noted that we have so far only studied carboh...Structural mechanism of cell enzyme revealed by UT Southwestern researchers
...articular cell enzyme finds its target and clearly carries out its role in the complicated process of cellular communication. The discovery could lead to the development of drugs that specifically target certain enzymes to prevent the onset of disease. The research, led by Dr. Elizabeth Goldsmith, professor ...Researchers discover molecular 'switch' that tells body to store or burn fat
...b) mice with a mouse strain called "asebia," which carries mutations in the SCD-1 gene. The fatty acids that SCD-1 synthesizes are also required for normal function of sebaceous glands, so its absence leads to the "absence of sebaceous glands," hence the name "asebia." Sebaceous glands are embedded in the sk...'Rock-paper-scissors' preserves biodiversity in bacterial neighborhoods
...tudied bacterium, Escherichia coli. One population carries a natural genetic element (called a plasmid) that serves as the blueprint to make an antibacterial toxin, or antibiotic, called colicin. The plasmid also encodes a protein that renders the bacterium immune to its own colicin and a protein that causes...New witchweed-fighting method, presented by CIMMYT and Weizmann Institute scientist
...eloped, using biotechnology, in the U.S. The corn carries a mutant gene that confers resistance to a specific herbicide, leaving the corn plant unharmed when treated with this herbicide. As an alternative to spraying entire fields, Prof. Gressel suggested that herbicide-resistant seeds be coated with the h...Aborigine study suggests body mass index guidelines should be lower to block diabetes
...better indicator of how much extra weight a person carries around as fat than their weight alone because, obviously, people of the same ages and weights vary considerably in height." In the new study, Daniel worked with Drs. Kevin Rowley of the University of Melbourne, Robyn McDermott of the Tropical Public ...Protein discovered that keeps hemoglobin in balance
...cell formation, specifically for hemoglobin, which carries oxygen in red blood cells. Understanding how this protein functions may eventually lead to novel treatments for the hemoglobin-related blood disease, thalassemia. Thalassemia is a group of related inherited disorders that together are the most commo......on a form of acute myelogenous leukemia (AML) that carries a bleak prognosis. They have identified two new drugs that inhibit a specific enzyme that drives development of the deadliest form of AML. It is hoped that the two drugs -- and others now in clinical trials -- will pack the same potent punch that has...