NIA makes second novel clone set available
... single laboratory. Use of the NIA cDNA clone sets carries no collaboration requirement that would constrain usage, so that all laboratories may have unencumbered access to the microarrays....Harden McConnell named winner of 2002 Welch Award in Chemistry
...asy problems," Hackerman told luncheon guests. "He carries out research on things that irritate him -- and obviously does a good job!" In acknowledging the award, McConnell noted that only "20 percent of my work was done by me alone." The other 80 percent involved collaborations with students andpostdocs, ...Protozoan chosen for genome sequencing
...on with humans about two billion years ago. Yet it carries many of the same genes as humans, and therefore can be used to understand the function of many human genes. Small as it is, Tetrahymena has about 30,000 genes, a similar number as humans. It reproduces quickly, doubling in numbers every two hours, wh...Researchers solve killer protein's 'crime'
...upon a startling finding regarding just how Reaper carries out its murderous task. Moreover, because cancer arises in part by outwitting programmed cell death, the results, reported in the June issue of Nature Cell Biology, may lead to novel strategies for putting this protective mechanism back into cancer...Jonathon Knight receives ASM Communications Award
...ness of the many facets of microbiology. The award carries a $2500 honorarium plus presentation of an award plaque at the General Meeting of the American Society for Microbiology. This years presentation will take place on May 19 in Salt Lake City.Judges for this years contest were Julia Ann Miller, editor,...Time to vaccinate everyone under 30 against smallpox?
...ne composed of live vaccinia (cowpox) virus also carries risks. Prior experiences with smallpox vaccine indicate that one in a million vaccinees is expected to die from severe complications of immunization, while many more will develop less severe side effects. Children under 1 year are not vaccinated for ...Hopkins scientists reveal how sound becomes electric
...nerve sends an electrical signal to the brain that carries information about the original sound. But the nature of the chemical burst has been a mystery until now." With the help of powerful microscopes, the scientists studied individual cells from rat cochleas, tiny coiled structures deep inside the ear whe...Leprosy bug provides clues to early nerve degeneration
...d, followed by the degeneration of nerve axon that carries the nerve impulses. M. leprae does not harm any other parts of the cell, and causes no signs of cell death. The researchers found that, unexpectedly, M. leprae does not need to enter the cell to cause degeneration of the myelin sheath. "This suggest...Researchers identify cell, genetic environment behind nerve-tissue tumors that lead to cancer
...er from them, Parada said. Every cell in the body carries a complete copy of the genetic code that controls human development. Included in that code are tumor suppressors whose function is to control unrestricted cell growth. People normally have two NF-1 copies (alleles), one contributed from each parents ...Protecting drinking water from disease transmission by means of zeolite filters
...ry a negative surface charge. Adding a filter that carries a positive charge to wells will cause the viruses to adhere to the filter, rather than being transmitted to humans who drink the water. Schulze-Makuch and his colleagues suggest, based on their experiments, that zeolites would be effective filter co...Manganese blocks HIV replication; Lab finding points to potential new class of HIV treatments
...ned that the defective gene is PMR1, whose protein carries both manganese and calcium out of cells. Using special yeast developed by others at Hopkins, he discovered that manganese stops reverse transcriptase, the team reports in the April 26 issue of Molecular Cell. "These results really point to a never-b...Link found between low birth weight and DNA from mothers
... deoxyribonucleic acid, the material in cells that carries the genetic code and transmits hereditary traits. "People tend to look at DNA as only being inside the nucleus of a cell. However, there also is DNA in the cytoplasm that surrounds the nucleus inside the cell membrane. Some of this DNA is found ...UB study finds early nutritional modification programs metabolism, predisposes to obesity
... found. Furthermore, this "metabolic programming" carries through to the next generation. Offspring of first-generation high-carbohydrate-fed (HC) female rats developed hyperinsulinemia (high insulin levels) and obesity without any dietary modification. Mulchand Patel, Ph.D., UB professor of biochemistry a...New tool speeds study of mammalian protein function
...ucted a special plasmid vector--a ring of DNA that carries foreign genetic material into cells. Once inside, the vector directs the enzyme RNA polymerase to make snippets of double-stranded RNA. These then bind to matching strands of messenger RNA, neutralizing it and causing it to be degraded, thus interfer...Scientists unravel complicated genetic disease in one fell swoop
... of what often is ignored: The part of a gene that carries instructions for making a protein (the coding sequence) isn't the only part that can contribute to disease. "Mapping gives you an independent way of saying that this gene is involved in a disease, even if there are no changes in the coding sequence,"...Social insects could offer clues about genetic conflict
...e placenta that favors the developing child -- who carries the fathers genes -- over the health of the mother -- who doesnt share the paternal genes. Maternally derived genes favor a smaller placenta that would protect the mothers health and her ability to produce future offspring who will carry on her genet...'Vigilant vector' could insert genes that sense, prevent heart attacks
...rrective genes into human cells, including that it carries no DNA of its own, Phillips said. The UF team spent two years developing the heart-attack-preventing gene switch using a combination of genes from human and yeast cells, Phillips said. Active only in heart tissue, the switch turns on the protecti...Scientists trace recently found genes to the evolution of big brains
...gene is expressed, is an important glial cell that carries out a key function in the newly formed brain. Oligodendrocytes, acting like molecular electricians, wrap the long, thread-like neuron with a sheath of myelin, a fatty material that acts like insulation around an electric wire, enabling it to transmit......eding can then produce animals in which every cell carries the extra DNA. When mice are modified by injecting DNA into their tails, Fogarty claims, 40 per cent of their offspring on average carry the extra DNA-an amazingly high proportion. Tosk's secret is jumping genes, or transposons, which are found in ......nant virus, Myb34.5, has this same defect but also carries an engineered form of the g134.5 gene. The product of this gene allows the virus to circumvent a host cell defense mechanism that would otherwise shut down protein synthesis in infected cells. In Myb34.5, g134.5 is expressed under control of the Myb ...