Pig-human transplantation not PERVerted
...cies into the donor. Particular attention, for the case of transplantation of tissues and organs from pigs, has been paid to a set of pig-derived viruses called PERVs (for Porcine Endogenous RetroViruses) because they possess the ability, though limited, to replicate in human cells. So far, the actually f...JCI table of contents: 1 September, 2004
...cies into the donor. Particular attention, for the case of transplantation of tissues and organs from pigs, has been paid to a set of pig-derived viruses called PERVs (for Porcine Endogenous RetroViruses) because they possess the ability, though limited, to replicate in human cells. So far, the actually f...Scientists fear new Ebola outbreak may explain sudden gorilla disappearance
...threaten tens of thousands of great apes in this case gorillas and chimpanzees in the Republic of Congo. The announcement was made by the International Primatological Society (IPS) and Great Ape Survival Project (GRASP) at the IPS's 20th Congress, being held this week in Turin, Italy. Congo's Odzala N...One-hundred-fifty year old lessons of John Snow still relevant today
...ugh Snow knew his way around a laboratory, in this case it almost didn't matter. "Snow said even if we can't identify whatever this thing is that causes cholera, we have enough information at our disposal to prevent further spreading of the disease," said Peter Vinten-Johansen, a history professor who ser......n. Our findings clearly show that this is not the case and will have widespread implications for HIV management, diagnosis and prognosis." This groundbreaking news is in part due to the development of a new technical tool that permits cloning of the virus....Environmental costs of home construction lower with wise choice, reuse of building materials
...analysis known as a life-cycle assessment. In this case researchers determined that the construction of a hypothetical Minneapolis steel-frame home used 17 percent more energy than the matching wood-frame home. Constructing the study's hypothetical Atlanta concrete-frame home used 16 percent more energy t...Researchers uncover secrets of immune system's munitions factory
...teps in these two different situations lead in one case to mutation and in the other case to recombination," he said. "Now that we know more about how AID links to the next steps through RPA...Computer database being developed at Temple will allow for better inventory of chemicals
...ormation that would prove especially useful in the case of an emergency such as a fire. The people in ...ing with and whats hazardous, he explains. In the case of an emergency, response personnel also need to know what theyre dealing with. For example, if you ...Tiny molecules have big potential as cancer drugs, Stanford researcher believes
...the latter is a particularly difficult task in the case of cathepsins because of the nature of proteases, Bogyo said. "Proteases take other proteins and degrade them into little bits, and so it's hard to figure out what those proteins were doing," he said. "We're beginning by focusing on individual protea...Decreasing toxins in brains of Alzheimer's patients keep cognitive deficits at bay
...s of a specific molecular weight and size, in this case isoprostanes. Applying a treatment for hydrocephalus to Alzheimer's disease, the microns-wide shunt, or catheter, is placed subcutaneously in a space at the base of the cerebellum. It runs under the skin to the peritoneum, a space in the belly where ...First clinical study of new pediatric croup vaccine shows safety, tolerability in adults
...ice carrying SeV, there has never been a confirmed case of SeV infection in humans."Using a natural mimic of a human virus follows in the tradition of the world's most successful vaccine, the smallpox vaccine, said Julia Hurwitz, Ph.D. member of the department of Immunology. "The smallpox vaccine was bas...U of T study identifies possible stem cells in pancreas
...d to the research. "This remarkable discovery is a case study in cross-Canada cooperation," says Dr. Ron Worton, Scientific Director of the Stem Cell Network. "The research offers considerable new hope for people living with diabetes."...Managing occupational exposures to potential bioterrorist agents
...ver, that these are guidelines only, and that each case must be evaluated individually. The USAMRIID team also compared their recent experience with data on laboratory acquired infections during the offensive biological warfare research program conducted by the U.S. between 1943 and 1969. During those ye...New understanding of the machinery of flinching
...or processing a particular set of stimuli--in this case those that represent a sudden approach of objects to the body. "PZ may provide an example in the motor system of a relative hotspot for the ethologically important function of defense of the body surface, although PZ may of course have other sensory ...New model can aid in understanding immune system diseases
...ls of the problems they want to study. Such is the case with Epstein-Barr, a common virus that is often harmless but likely contributes to malignancies and autoimmnune disease in people with compromised immunity. A University of Iowa team has engineered a mouse that provides new insights into the virus. ...Retroviral gene therapy? ASLV, HIV, and MLV show distinct target site preferences
...e for human gene therapy. Mitchell et al. make the case that scientists can gain more control over where viral vectors integrate into the human genome by selecting different retroviral integration systems. Only time will tell whether more control translates into safer gene therapy protocols....Technology already exists to stabilize global warming
...sible until the warming is upon us or not, as the case may be," Pacala continued. "The alternative to act... find out how accurate we were." A strong case for action comes from three lines of evidence, said Pacala. First, investigations of the Earth's cli...Applied Mathematical Models in Human Physiology
...emic arteries. The models presented can be used as case studies in courses on mathematical modeling or as ...d pulmonary system. Each model is introduced by a case study and can be studied individually. This book serves as an excellent introduction for researche...Size does matter when choosing a mate
...mal kingdom and we are already finding this is the case in other bird species we are studying such as Bustards," said Szekely. "There's no reason why it would not apply in many other animals from gorillas living on the rainforest floor to monkeys living high up in the canopy too." Shorebirds, gulls and au...Preschool bolsters early childhood immunity, reduces risk of young adult Hodgkin's lymphoma
... children spend time in close proximity, as is the case in day care and nursery school settings," added Chang. "This frequent contact appears to prime the immune system toward a more mature type 1 response than is found among children of the same age who have less social interaction with their peers. It...