Advances in tumor angiogenesis Dendritic cells co-opted to the dark side
...opted into tumor angiogenesis. "When the dendritic cell precursors are put in the tumor context they form ...f the proteins beta-defensin and VEGF-A, dendritic cell precursors were attracted to the tumor, where they turned into an endothelial-like cell type. Endoth...Washington University in St. Louis plays key role in sequencing moss genome
...nique experimental features include few and simple cell and tissue types, ease in growing and undergoing sophisticated genetic manipulation including the capacity of this organism to integrate transforming DNA by homologous recombination at frequencies higher than that of any other multicellular eukaryote...Integrative biology of exercise APS Intersociety meeting October 6-9, 2004 in Austin
... Striated muscle hypertrophy: factors controlling cell enlargement and phenotype transformations. Chair Kenneth M. Baldwin. AMP-activated protein kinase: regulation of metabolic and transcription processes in contracting skeletal muscle. Chair Neil Ruderman. Comparative biomechanics and muscle functi...Columbia, Stony Brook, Guidant to develop biological pacemaker based on gene & cell therapies
...niversity will collaborate to study a new gene and cell therapy that may ultimately provide better understanding of how genetically-engineered cells can help pace the heart. This five-year, phased investment will build on recent basic research conducted at the universities. The goal of the program is to d...Protein fishing in America: The movie
...tein important in cells that depend on calcium for cell signaling, that can bind with various protein species. Lu's group has assembled an elaborate instrument at PNNL's W.R. Wiley Environmental Molecular Sciences Laboratory. In the instrument, fluorescent-dye-tagged proteins are embedded in a gel and pro...Review article makes case for a new source of cells in the body
...as P. Dickinson, molecular biologist, says of this cell type that escapes from the bottom of the neural tu...ring development, they differentiate into the same cell type as their neighbors. So they potentially just vanish into the crowd," says Dr. Dickinson who fir...University of Pittsburgh receives $10 million grant for head and neck cancer
...amine alterations in a DNA repair gene, XPD, and a cell cycle regulatory gene, cyclin D1, that previous re...protein, BCL-X, that interferes with apoptosis, or cell death. By targeting STAT signaling, the researchers hope to inhibit the progression of head and neck...OHSU-VAMC study sheds light on estrogen's benefit for MS
...ogen treatment simulates pregnancy in increasing T cell levels. It also demonstrated that estrogen boosts ...xP3 protein not only in a mouse model, but also in cell culture. "In vitro, estrogen can induce regulatory cells," Offner added. In their research, the OHSU...Researchers uncover secrets of immune system's munitions factory
.... The presence of an antigen on the surface of a B cell stimulates it to produce antibodies. An important ...erstanding lymphomas. "Lymphomas and some mature B cell tumors are known to show aberrant somatic hypermutation and class switching," said Alt. "Now that we...Images reveal how rotavirus - leading cause of diarrhea - enters cells
...hanges that allow it to breach the membrane of the cell it's trying to infect. "This protein goes throu...orm a rigid spike, priming the virus to attack the cell and positioning the spike "head" to bind to the surface of the target cell. Then, in a second rearra...Meteorites supplied Earth life with phosphorus
...hitecture it is in the phospholipids that make up cell walls and in the bones of vertebrates."In terms of mass, phosphorus is the fifth most important biologic element, after carbon, hydrogen, oxygen, and nitrogen," said Matthew A. Pasek, a doctoral candidate in UA's planetary sciences department and Lun...Listen up! Mice may hold key to restoring human hearing loss
...d, the cells do not easily grow back. And with the cell loss comes so-called irreversible hearing loss. ... the mouse inner ear to establish long-term stable cell lines. This is the first step toward the ultimate goal of creating implantable human hair cells that...Bright idea could doom cancer and viruses, say Purdue scientists
...ds bind DNA in the cellular nucleus and render the cell unable to reproduce, effectively destroying it. The trouble is, such chemicals also kill many other healthy cells in the body in the process. "That's the reason cancer patients often lose their hair," Morrison said. "Hair cells, like many others in t...Regular physical activity really does boost immune system in older men
... as well as an age-related decline in the memory T cell response to KLH. The older physically active subje...ggests that aging produces declines one specific T cell sub-type (Th1) that is essential for the generation of IgG1 in humans and that a physically active l...Trojan Horses, xenon imaging and remote controlled genes
...is to alter protein expression within a particular cell and at a particular time during development," Dmochowski said. "It means that researchers could turn specific genes off like a switch in order to find out the nature of a gene by what happens when it does not work."...Light turns on anticancer agents
...n Brewer's chemistry-biology group is working with cell cultures to compare the effectiveness of the agents in the dark and in visible light. "Another improvement for our systems is that the agents are activated by visible light, as opposed to UV light," said Brewer, associate professor of chemistry. "Usi...UV light, coatings reduce bacterial adhesion up to 50 percent
...at the lower wavelength UVC light (254 nm) lowered cell adhesion by 15 to 50 percent, depending on the type of bacteria, on both the titanium dioxide and tin dioxide coated surfaces. The higher wavelength UVA light (340nm) produced similar effects for glass coated with titanium dioxide but not with tin di...Synthesized molecules studied as weapon to stop cell division in cancer cells
...23, 2004 -- An enzyme called Pin1, a gatekeeper of cell division, is present at high levels in a wide vari...ates the protein Cdc25, which initiates mitosis or cell division. Without Pin1, the cell enters programmed cell death -- which is good if it's a cancer cell...Engineering endurance: The future of the Olympics?
...sphate (ATP), a molecule that fuels many essential cell processes. A number of metabolic pathways supply muscle tissue with the ATP needed to power muscle contraction and sustain ongoing exercise. Which pathway predominates depends on factors like speed, duration, and type of activity, as well as on the a......hibitor called zebularine--is better at inhibiting cell growth and promoting gene expression in cancer cel...lation silences a gene that normally would control cell growth or prompt the cell to commit suicide, then the cell will grow unchecked--the hallmark of canc...