Jefferson Scientists Find Potential Deadly Effects Of Two Missing Cancer-Suppressor Genes
...destructing. As many as 60 to 90 percent of the cells underwent apoptosis." Men have an X and a Y ...is some damage to the X and other chromosomes when cells duplicate and go through a "cell cycle." Cells have an innate repair mechanism to fix the prob...A New Biochemical Link Established Between Stress, Sex And Dominance
...n the head All of this is reflected in a patch of cells in the fish's brain that increase eight-fold in vo...us as well. The colors and eyepatch fade, the GnRH cells in the brain shrink and so do the gonads. "In our lab, we have shown that behavior influences the b...Common Childhood Virus Poses Threat To Adults, Research Shows
...lated.” The RSV virus attacks the epithelial cells that line the airways in thelungs. It spreads as people cough up infected epithelial cells, so handwashing is the best way to limit the spread of RSV. RSV is the leading cause of severe lower respiratory tract infectionin infants and young children....MGH-Led Team Finds Gene For Crippling Neurologic Disorder
... organisms, the heat-shock proteins/proteases help cells recover from stresses including heat, traumatic injury and chemical poisoning. Until now, no human disease has been associated with these proteins. "This is quite exciting, because it may help us understand how stress situations bring on a variety ...Pea Plant Stem Growth Gene Cloned
...zyme crucial to the division and elongation of the cells in the plant's stem. Researchers Diane R. Lester, a molecular biologist; John J. Ross, a plant physiologist and James B. Reid, professor of genetics, all at the University of Tasmania, and Davies, will publish "Mendel's Stem Length Gene (Le) Encodes ...Discovery Of Genetic Pathways May Provide New Ways To Combat Candida Infections
...ates recently captured on video the fate of immune cells infected with Candida in a petri dish. When Candida enters a host, the organism is eaten up by cells called macrophages, which are the sentinels of the immune system. But soon, the fungi fight back, s...Molecular Piracy Turns Protein Into Traitor
...all main co-receptors used by HIV to gain entry to cells (CCR5, CCR3, CXCR4 and US28). Full details of the ...ater on, HIV mutatesallowing it to gain entry to T cells through CXCR4. Biologically, the virus appears to have optimised vMIP-II to block leukocyte recruitm...Trojan Horse Virus Controls Hiv Infection
...Trojan horse that selectively targets HIV-infected cells and thendestroys them. As reported Sept. 5 in the...ely controlled HIV infection in laboratory-grown T cells anddramatically reduced infectious HIV to levels that were barely or no longerdetectable. "This is a...Low Oxygen, Key To Fetal Development, Also Offers Cancer Clues
...nancy. The team studied cytotrophoblasts, the cells from theplacenta that form the connection between mother and fetus byattaching to the uterus. These cells eventually evolve intotumor-like cells that invade the mother's uterus and establishblood flow to th...Wonder Thread: UD Scientists Report First Protein With Collagen And Elastin-Like Domains
...D. They used pepsin, an enzyme secreted by stomach cells of vertebrates, to pinpoint the collagens. Unlike most proteins, Waite says, Col-P and Col-D don't break apart in response to pepsin. Since pepsin works best in an acidic environment, researchers simply placed byssal threads and pepsin in a weak solu......f mice who lack the D4 receptor. "Branching nerve cells communicate with each other by secreting chemicalm...pamine that bind to receptors on neighboring nerve cells in alock-and-key fashion," explains, David Grandy, Ph.D., OHSU scientist and seniorauthor of the art...Gene For Last Major Form Of Batten Disease Discovered
...m the neurons. Since neurons don?tdivide as other cells do, they are unable to reduce their load of undigestedproteins. A second possibility is that the normal enzyme is required to producesomething neurons need to survive, such as a nerve growth factor. The researchers are now developing DNA and protein...Smoking Mice Lead To Emphysema Breakthrough
...at emphysema was caused byneutrophils, white blood cells that destroy foreign invaders and, occasionally,ca... macrophages played arole in emphysema because the cells seemed incapable of destroying sturdy lungtissue. But recent experiments by Shapiro and others showe...Plant-Based Therapies Examined For Colon Cancer Prevention
...ent antioxidantsand antiinflammatories, can affect cells in a similar manner as sulindac, whichprompts the cells to "turn on" a program of regulated cell death calledapoptosis. NSAIDs, which include ibuprofen and...New Mechanism To Explain Carbon Monoxide Poisoning Identified
...ing oxygen delivery to the body'scells. Eventually cells essentially suffocate and die. "This traditional v...An excess of NO, however, is deleterious to brain cells and othertissues. "The amount of nitric oxide in the cell interior rises because carbonmonox...Report Notes Difficulties In Eliminating E. Coli O157:H7 From Food Supply
... document's authors. Less than ten E. coli O157:H7 cells may cause foodborne illness in people. Infectious doses associated with this pathogen in outbreaks have beenconsistently low?a characteristic associated with the organism's acid tolerance,according to Buchanan and Doyle. Unlike most other pathogens, ...Study: Hydrogen Bonds Aren't Key To DNA Pairing After All
... to thwart the enzymes that copythe genes of tumor cells and viruses. The work was supported by the National Institutes of Health....Bowman Gray Scientists Find Novel Way To Block AIDS Virus
...-receptor on the surface of particular white blood cells calledlymphocytes is blocked, making the cells immune to infection by HIV-1. HIV-1 virus causes AIDS by invading and destroying the white b......mmune system and, in fact, directly infect thevery cells tasked with defending the body against infection. ...vely induces apoptosis inneighboring immune system cells that have not yet been infected, known as CD4 Tcells. It also interferes with the ability of those c...... challenges awell-established idea about why nerve cells self-destruct when the brain orspinal cord is inju...will open up new possibilities forprotecting nerve cells in patients who suffer stroke, head injury, spinal cordinjury or neurodegenerative disorders such as...