Newly identified gene linked to brain development
... the evolution of the frontal lobes of the brain's cerebral cortex. The findings, reported in the March 26, 20...opment and the evolution of human behavior. "The cerebral cortex is the part of the brain that distinguishes humans from other species," explains the study's ...Researchers identify a new form of disease gene associated with Rett syndrome
...usion' in other developmental disabilities such as cerebral palsy, forms of mental retardation and autism, we expect this new discovery to have great clinical utility," added Dr. Minassian. Kathy Hunter, president and founder of the International Rett Syndrome Association (IRSA), applauded the new paper: "Thi...... humans, they demonstrate accelerated physical and cerebral development, remain fertile into old age and experience few brain-aging changes relative to the devastation of Alzheimer's seen in humans today. Finch and Stanford argued that the new human apoE variants protected the chimpanzees. In a series of "ev...Alcohol consumption can damage hearing
...age has also been noted in specific regions of the cerebral cortex hypothalamus and cerebellum, and possibly in the hippocampus, amygdala and locus ceruleus. "Many of the regions that are normal in alcoholics are damaged in those who have developed the Wernicke-Korsakoff syndrome," she added. "While documen...Mix of chemicals plus stress damages brain, liver in animals and likely in humans
...ustained significant damage in this study were the cerebral cortex (motor and sensory function), the hippocampus (learning and memory) and the cerebellum (gait and coordination of movements). Abou Donia's earlier studies demonstrated severe damage to the cingulate cortex, dentate gyrus, thalamus and hypothala...New study seeks to establish mechanism between areas of the brain and continence
...stimulation of the motor cortex, the region of the cerebral cortex most nearly immediately influencing movemen...oor to direct stimulation of the motor cortex, the cerebral cortical activity map related to voluntary contraction of this sphincter, could be quite different f...Key advance reported in regenerating nerve fibers
...wn as inosine to switch damaged nerve cells in the cerebral cortex into a growth state. In 2002, they reported that inosine helped stroke-impaired rats to regrow nerve connections between brain and spinal cord and partially recover motor function. ...Gene may be key to evolution of larger human brain
...layed a role in the expansion of the human brain's cerebral cortex -- a hallmark of the evolution of humans fr...icrocephaly a severe reduction in the size of the cerebral cortex, the part of the brain responsible for planning, abstract reasoning and other higher brain fu...JCI table of contents, January 2, 2004
...factor for stroke and increases brain damage after cerebral ischemia. The underlying mechanisms remain unclear...diabetic mice suffered less brain damage following cerebral hypoxia-ischemia than male diabetic mice, Susan Vannucci and colleagues from Columbia University in ...A big surprise: Young nerve cells can rewind their developmental clocks
Scientists have identified a gene in the cerebral cortex that apparently controls the developmental ... gene is eliminated in embryonic mice, the brain's cerebral hemispheres barely develop. Subsequent work demonstrated that the gene played a role in the early ph...Discovery of brain disorder gene paves way for genetic test
...can each independently cause the disorder known as cerebral cavernous malformations (CCM), which is characterized by mulberry-like clusters of blood vessels in the brain. The finding paves the way for a new genetic test for the rare, familial disease, which typically lies dormant in patients for decades befor...Aging: The continuous process from birth to death
...erebrovascular Tone and [Ca2+]i," examines whether cerebral artery tone and intracellular Ca2+ concentration (...[Ca2+)i] are affected by aging, using the isolated cerebral arteries of rats for investigation. The conclusions of the research team Greg G. Geary and John N. B...Investigational cancer drug prevents abnormal brain growth, reverses seizures in lab mice
...d nurture nerves. This cancer occurs mostly in the cerebral hemispheres of adults, but can also occur in the lower brain and spinal cord of children. There is no effective treatment for this cancer. The St. Jude team used a mouse model to show that CCI-779 could prevent enlargement in the brain cells of youn...New technique helps shed light on progression of dementia
... used this sort of model to look at the effects of cerebral blood flow disruption on mental functions that require intact nerve cells releasing acetylcholine in the cortex. In patients with dementia, blood flow in the brain may slow down as a result of mini-strokes and the abnormal regulation of blood vessels...Researchers discover genes that distinguish human, nonhuman primate brains
...a Los Angeles (UCLA), has identified genes in the cerebral cortex that differ in levels of activity between h...cies. Using gene chips to compare samples of the cerebral cortex of humans, chimpanzees and rhesus monkeys, the research team at the Salk, the Yerkes Center a...New gene for rare inherited paralysis may aid other spinal cord research, too
...her nerve disorders, including multiple sclerosis, cerebral palsy, and amyotrophic lateral sclerosis (also cal...elops in early childhood and may resemble familial cerebral palsy. That discovery, of a gene on chromosome 14 that encodes a protein called atlastin, has alread...Toxic protein could explain Alzheimer's and lead to breakthroughs
...diagnostics capable of detecting ADDLs in blood or cerebral spinal fluid. Currently diagnosis of Alzheimer's is based primarily on a battery of psychological tests. "Now that ADDLs have been discovered in humans we would like to develop effective diagnostics and that means employing nanotechnology," said Kle...Study points to new gene therapy tool in preventing epileptic seizures
...y remain localized or spread to other parts of the cerebral cortex.The temporal lobes, one on each side of the head just above the ears, are the brain sites of one of the most common forms of epilepsy involving focal seizures. "Epilepsy afflicts approximately 1 percent of the U.S. population. A large proporti...Study sheds light on critical relay in visual circuit of the brain
...y brain defects that are linked to conditions like cerebral palsy and learning disabilities. During developmen... passes these messages on to the area of the outer cerebral cortex that deals with vision. The connection between the thalamus and cortex initially passes throu...Study links amyloid plaques in Alzheimer's brains to genes vital to normal memory
... the brain containing amyloid, the hippocampus and cerebral cortex, but remained unchanged in amyloid-free regions of the brain. The researchers then compared their findings in the mouse model with an analysis of human Alzheimer's disease tissue from the Brain Donation Program at Sun Health Research Institute...