Gladstone investigator Mike McCune wins prestigious NIH Director's Pioneer Award
...unodeficiency. "Now I want to know if there are certain types of immune responses that protect against infection and others that might instead slow down the pace of disease," he explains. "Perhaps more importantly, I want to apply this knowledge to the creation of a vaccine that will prevent people from d...DNA lends scientists a hand, revealing new chemical reactions
...les are directed by enzymes that selectively bring certain biological reactants together. Liu and his colleagues use DNA as a similar type of intermediary to bring together synthetic small molecules that are otherwise too dilute to react, allowing minute quantities of sparse molecules to behave as denser mix...Pack-MULEs are toting a new look at plant evolution
...ping genes" of plants. The genome sequence is in a certain order. Change the order of the genetic material and a function can be changed. Transposable elements are sort of the rowdy kids in a classroom their insertion may disrupt an orderly gene. Jiang offers Indian corn as an example. An ear of Indian corn...Alzheimer's disease is not accelerated aging
... lots of data points converge suggesting there are certain changes that take place in aging that are not what cause Alzheimer's disease." Buckner is the author of a review article published in the September 30, 2004, issue of Neuron, that points out recurring distinctions between factors that influence what...New molecular link key to cellular proteins involved in cancer progression, other diseases
...t and progression of diseases including cancer. In certain cancers, including prostate cancer and lymphomas, ...d may identify a potential target for treatment in certain cancers," said the study's senior author Dr. Yi Zhang, associate professor of biochemistry and bioph...Safety of isoflavones in dietary supplements targeted by Illinois initiative
...causes thymic atrophy and immune dysfunction under certain conditions. Susan L. Schantz, professor of veterinary biosciences and of psychology, and Donna L. Korol, professor of psychology, will direct research on the effects of phytoestrogens on brain tissue and cognitive function, including cognitive...Award winning researchers reveal potential new role for Glivec
... DFSP tumours have t(17-22). "It's difficult to be certain based on only one case, which was very high grade and where there was also the possibility that it may not have been a true DFSP, but our patient without the translocation did not respond to imatinib. Nevertheless, our data support the use of imatini...Researchers identify protein promoting vascular tumor growth
... "Previous work in our lab has shown that a certain form of berry extract significantly regulates MCP-1 function," said Sen, who served as a mentor to Gordillo on this research. The trick will be regulating MCP-1 levels safely, because the protein also is called to action to help wounds heal....UCSF scientist Joe Derisi named MaCarthur Fellow
...nes expressed only once during the stage, and in a certain order, for a simple, continuous cascade of gene expression, beginning with genes that correspond to normal cellular processes and ending with highly specialized functions for invading red blood cells. The discovery of the pronounced level...Newly identified master gene key in baby's first breath
...ress syndrome and in many cases, death, was almost certain to follow, said Jeffrey A. Whitsett, MD, chief of Neonatology, Perinatal and Pulmonary Biology at Cincinnati Children's and senior author of the study that appears in the October 5 issue of the Proceedings of the National Academy of Sciences (PNAS). ...Marijuana use could cause tubal pregnancies
...mans. Dey and his colleagues plan to study whether certain polymorphisms also may reflect an increased risk for ectopic pregnancy. "That will be the ultimate test" for proving the receptor's role in ectopic pregnancy in humans, he says....UCI scientists successfully target key HIV protein; breakthrough may lead to new drug therapies
...stem, making the body vulnerable to infections and certain cancers. Symptoms of acute HIV infection may include fever, headache, fatigue and enlarged lymph nodes. The virus is spread most commonly by having unprotected sex with an infected person. Funded by the Arnold and Mabel Beckman Foundation, the Burrou...Anthrax enzyme images reveal secrets of antibiotic resistance, suggest new drug design
...DHPS. In addition, they created images showing how certain small enzyme mutations allow it to alter its structure, blocking the attachment of sulfa drugs. The image showed that while this slight change in the shape of a small part of the enzyme made DHPS resistant to sulfa drugs, it did not disrupt the enzym...Brown research reveals key insight into memory-making
... events and word meanings. Scientists believe that certain forms of mental retardation and diseases such as Alzheimer's are linked to nerve cell dysfunction in the hippocampus. The new research provides new targets for drugs or other treatments for these conditions. Esther Penick and Jeffrey Edwards, postdoc...Scientists find nanowires capable of detecting individual viruses
...ucting a small current with antibody receptors for certain key domains of viruses - such as agglutinin in the influenza A virus. When an individual virus came into contact with a receptor, it sparked a momentary, telltale change in conductance that gave a clear indication of the virus's presence. Simultaneou...Certain genes boost fish oils' protection against breast cancer
...r cancer. "In this study, we found that women with certain common DNA patterns experienced more breast cancer...ied a novel gene-environmental interaction between certain genotypes and omega-3 fatty acids on breast cancer development," says Mimi C. Yu, Ph.D., professor o......better than apples, but oranges cost more. Given a certain budget for fruit, the utility function says how many of each you should buy. Similarly, Krding and colleagues observed people's preferred movements, then inferred an underlying utility function that presumably describes bias in the nervous system for...Key stimulator of colorectal cancer identified
...mulate PPARd may encourage abnormal cell growth in certain populations at risk for CRC. In addition, it is possible that blocking PPARd might prove useful for prevention and/or treatment of CRC." ...Research suggests new avenue for stopping, preventing colon cancer
...e PPARdelta "may encourage abnormal cell growth in certain populations at risk for colorectal cancer," DuBois cautioned. DuBois credited Sudhansu K. Dey, Ph.D., who directs the division of Reproductive and Developmental Biology at Vanderbilt, with maintaining the PPARdelta "knockout" mouse colony that made t...Brown ecologist garners major National Science Foundation grant
...t when plants will flower and which will thrive in certain regions. Then, with the help of students sent for training in seven leading European Arabidopsis labs, all 200 weed varieties will be planted in six test sites one in Finland, one in England and two each in Germany and Spain to see which varieties ...