Hopkins to found first center for comprehensive study of epigenetics
...es on or off. "Epigenetics may be as important in certain conditions, or in contributing to the risk of developing certain conditions, as the genetic sequence is in other cases," says Andrew Feinberg, M.D., King Fahd Profes...Carnegie Mellon U. imaging study reveals sex-based differences that persist as mice enter adulthood
...e, show that sex hormones alter the development of certain brain structures during puberty and that these effects persist into adulthood. The findings provide a much truer representation of how circulating hormones affect brain structures than could be derived from human imaging for several reasons, acco...Biologists ID defense mechanism of leading fungal pathogen
...s, including AIDS patients and patients undergoing certain types of treatment for cancer. In cases where Candida infections spread to the bloodstream, mortality rates climb as high as 50 percent. Candida's defense against NO relies on enzymes called flavohemoglobins. Gustin's research involved a test of thre...Scientists discover genetic marker responsible for two-fold increase in risk of rheumatoid arthritis
...Dr. Gregersen, a genetic variant in the setting of certain environments and in the presence of other genes may have harmful effects, whereas the same genetic variant may have beneficial effects in another genetic and environmental context. "So this particular genetic variation may have contributed to the sur...Joslin researchers identify key molecule in Type 1 diabetes progression
...does not ("respectful" insulitis). They know that certain T-cells called T effector cells promote destructiv...es Center in Boston studied insulitis lesions in a certain strain of genetically engineered mice called BCD2.5 mice. These mice develop insulitis, but a very ...New insight into cancer metastasis
...to determine levels of gene expression, they found certain genes that were active only in the metastatic cells. The gene that stood out among all the others was one coding for the protein Twist. Next, Yang isolated highly metastatic cancer cells and disabled the Twist gene. When she injected these...'Mighty mouse' gene works the same way in people
...ty own MetaMorphix Inc. stock, which is subject to certain restrictions under University policy. Lee owns Cap...quaculture Technologies stock, which is subject to certain restrictions under University policy. Lee has served as a paid consultant to MetaMorphix Inc. The te...$5 million grant funds partnership, studies of minority-based issues in reproductive health
...minorities that are disproportionately affected by certain reproductive disorders." Three of the clinical studies that are part of this grant are currently recruiting participants. One study aims to determine whether female hormone levels are higher in African-American compared to Caucasian females. The stud...Protein believed to control formation of memory identified by Scripps & UCSD scientists
...otein. Mutations in CREB prevent the activation of certain genes, and animals with defective forms of CREB have problems forming long-term memories. But, scientists asked, was CREB the only protein that controls memory formation? A few years ago, Korzus and Mayford were working at the UCSD School of Medici......ity and fertility problems, as well as what causes certain birth defects. Molecular control of the step-by-step process of how the zebrafish body unfolds relies to some extent on maternally driven processes. These depend on proteins derived only from the egg, which are critical to embryonic dev...Energy conservation targets hit by notions of 'comfort'
... on shape future expectations and lock people into certain comfort regimes for the life of the building....UK small firms pay lip service to green issues
... 'Legislative sanctions are clearly one way to be certain that the environment becomes a top business priority for small firm owners,' says Revell. ' Regulation makes the environmental obligations of firms clear from the start, and offers SMEs the security of a 'level playing field' so that environmental go...Biocompatibility to widen scope of biomaterial applications
...mers and modify properties of polymers by changing certain variables such as temperature, pH factor, ultraviolet light, and solvents. Other exciting research prospects include the development of customized organic polymers that can be used to regenerate damaged nerves. Research on visual prostheses promises ...North Shore-LIJ research collaboration with Correlogic Systems to advance ovarian cancer blood test
...kenazi Jewish women, who may be at higher risk for certain cancers, including ovarian cancer....Scientists discover new role for tiny RNA in plant development
...g. All microRNAs "down-regulate" the production of certain proteins by interfering with messenger RNA in several ways. One of the mysteries about microRNAs is why they have been conserved through evolution for so long; they are thought to have first evolved before animals and plants broke out into separate e...Myths surrounding Cuyahoga River fire 35 years ago
...and inaction to enforce them for decades--enabling certain industries to continue to pollute with immunity against prosecution and the less civic-minded continued to dump waste into the waterway. Cleveland's hands had been tied where state laws overrode local authority and did not allow the city to take acti...Harmless virus helps slow HIV by boosting immune proteins
...th HIV. The cells with GBV-C showed an increase in certain chemokines, or immune-system proteins. These proteins bind to the same white-blood-cell receptors-molecular "docking sites"-used by HIV. When the receptors aren't available, HIV is unable to infect the cells. When the researchers neutralized the che......, vast chunks of DNA can be added if desired. "For certain diseases it could be very useful to have the ability to deliver multiple therapeutic genes," says Gil Van Bokkelen, chief executive of Athersys in Cleveland, Ohio, one of several teams worldwide trying to develop artificial chromosomes. Most, like At......ble--only a region that in some ways has reached a certain maturity could produce, and make use of, such a volume."...Study finds first evidence COX-2 enzymes can regulate DNA damage
...which are known to be involved in the formation of certain human cancers. Interest in the potential use of COX-2 inhibitors as anticancer agents was fueled in part a decade ago when an American Cancer Society study showed that regular use of aspirin led to an unexpectedly low incidence of colon canc...