Gene Orchestrates Heart Chamber Development
... how expression of these genes is restricted toone chamber or the other, Cepko says. A developmental neurobi...expect Irx4 to be the master regulatorof heart chamber development. "This is an opening into how the heart develops,how the different chambers form. Other ...Heart Disease Symptoms Worsen When Body Tries To Adapt
...l of the leftventricle -- the heart's main pumping chamber -- thickens, leaving little roominside the chamber for blood to fill. The wall also can stiffen, furtherimpairing the heart's ability to contract. ......nes of pigs, then shut the animals in a hyperbaric chamber tosimulate the effects of ascending from a three-hour dive at around 240 metresbelow the surface. Pigs that were not given the bacterial cultures were nearly twice aslikely to show symptoms of decompression sickness. The treated pigs were als...Researchers Analyze Role Of Shear In Turbine Passage
...onship between water velocities within the turbine chamber and injuries tofish. Pacific Northwest researchers are studying one particular phenomenoncalled shear force, which occurs when two different water velocities collide. Depending on the shear's intensity, a fish may be disoriented momentarily, loseits......as been put in an orbital environmental simulation chamber on theground with a real-time linkage to the seed container aboard Columbia. "What we're trying to do is to treat these two batches of seedlings thesame, except that one will be exposed to one G of gravity and the other tomicrogravity." ...PCB exposure is bad news for the female sex drive
...feel like mating, they could escape into thesecond chamber through a hole too small for the larger frustrated males tofollow. It turned out that females exposed to A1221 left the males more oftenand took longer to return after each copulation attempt by the males (Bulletinof Environmental Contaminati...New technique builds microscopic medical devices for transplants
...tion of IgG in the second chamber was less than 0.4 percent. After four days,the ... of 1 percent to accumulate in the second chamber after only 24 hours. He added that keeping out 10......ional memory in the mice. The animals wereput in a chamber where they received mild shocks to their feet. When the micewere put back in the chamber one hour, one day, or 10 days later, the transgenicmice had a much more pronounced fear response tha...Stressed-out mice offer clues to depression, anxiety, anorexia
...e CRH-BP gene wereless likely to leave a protected chamber and spent much less time exploring openareas of an experimental maze than did normal male mice. "This test is based onthe animal's natural tendency to explore its environment in the absence of aperceived threat and to retreat to an enclosed area whe...Zebrafish's powerful heart gene could lead to transplant therapy
...s its divisions into two chambers, the atrium (the chamber that receivesblood and passes it to the ventricles) and the ventricle (the pumpingchamber). This work will allow the researchers to formulate specifichypotheses regarding the various cell interactions and molecules involved inthese processes. The fi...Scientists map brain's primary memory network
...he brain." The rats are tested in an experimental chamber with two bars or levers positioned on a single wal... it is rewarded. If the wrong lever is pressed the chamber goesdark for five seconds and a new trial begins. "The uniqueness of this situation is that the ani...Unique study reveals new details on how genes are transcribed
...lling the exchange and flow of liquids through the chamber and manipulating the laser trap can then be used to apply force on the beads, and the results can be measured through video microscopy. This unique experimental system enabled the researchers to make direct observations of the RNAP transcription pro...Monkeys pay one another for work
...ed how same-sex pairs of brown capuchins in a test chamber cooperatively work for food when separated by a mesh partition. Two transparent food bowls, one containing apple slices, were positioned in front of the monkeys on a weighted tray. An individual monkey could not pull the tray within reach on its own......tors. Michael Dickinson tracks blowflies in a test chamber to determine how feedback from their eyes affects the flight muscles and ultimately allows spectacular maneuverability. And Mimi Koehl builds foot-long models of lobster antennules to learn how these crustacean noses pluck odor molecules from the wat...Heart failure patients with worst heart function are good candidates for pacemakers
...as dilated cardiomyopathy, in which the lower left chamber of the heart becomes severely stretched and weakened. The amount of dissynchrony between sides of the heart among heart failure patients with a blockedbranch was found to be 10 times that of normal patients, proving a strong predictor for benefit fro...Vapor-recovery system captures and recycles air pollutants
...ils off the fabric, condenses on the inside of the chamber and drains into a collection vessel for recovery and reuse. Because electrothermal desorption does not require an adsorbent drying step, the regeneration process can be faster and more energy efficient than conventional desorption techniques used wit...Global warming: lessons taught by snails and crabs
...y raising the water temperature in an experimental chamber by 1.8 F (1 C) every 15 minutes, then examining the number of survivors at each temperature interval. ``The rate of 1 C per 15 minutes reflects the temperature increase that porcelain crabs experience during extremely hot low tide periods,`` Somero e...First gene therapy to calm pigs' out-of-sync hearts
...seased hearts, however, heart rhythms in the upper chamber may get altered in such a way that the filtering/relaying ability is overwhelmed. This can lead to abnormally fast, irregular heart rates. The researchers picked a gene, called an inhibitory G protein gene, because it switches on in pacemaking tissu...Chemists describe "zipper teeth" of DNA molecules -- publish results in the journal Nature
...t first remove the other factors. We used a vacuum chamber so that not even air molecules can influence them. This is the first time that scientists have been able to look at individual base pairs. From this we can already say that there is just one way that they bond." The researchers were also able to see......40 percent of the left ventricle (the main pumping chamber of the heart) is damaged, the patient ultimately dies. In their search for a way to reverse the damage, the team began by isolating bone marrow stem cells from male mice. The isolated stem cells carried a newly inserted gene that produces green fluo...