Gene expression profiling may predict head, neck cancer recurrence
...rovides insights into how the cell responds to its changing needs. A microarray is a tool for analyzing gene expression that consists of a small membrane or glass slide containing samples of many genes arranged in a regular pattern. It works by exploiting the ability of a given mRNA molecule to bind specifica...Stem cells toward sperm cells and back again
..." signal for stem cells can be turned on or off by changing the temperature around them. In experiments to examine what happens when the signal is turned off and then turned back on, second-year graduate student Crista Brawley discovered that cells that are two steps -- but not more -- away from their stem ce...A new way to kill cancer: SLU research shows viruses can destroy lung, colon tumors
...eral new "adenovirus cancer gene therapy vectors," changing these genes so the virus will attack cancer cells. "Some of our vectors are designed to destroy many different types of cancers, others are designed to be specific to colon or lung cancer. In preclinical testing these vectors were highly effective ag...Bird's eye views earth's magnetic lines
...s published in Nature , Phillips' lab showed that changing the color of light altered directional information obtained from the magnetic compass in amphibians, and that the photoreceptors responsible were not located in the eyes, but in the pineal organ, or "third eye," located on top of the head. For a pho...Study examines future of species extinction, conservation
...es that disappears - it alters entire communities, changing both how the community as a whole and the individual species within it will respond to environmental degradation, according to results published in the May 13 issue of Nature. With extinction continuously altering the fates of plants and animals, the...Botulinum toxin structure offers clues for vaccines/treatments
...n the toxin's mechanism of action. In addition, by changing just one amino acid of this portion of the toxin protein, the scientists have created a form with essentially the same structure but with no toxicity. "This achievement gives two opportunities for developing therapeutic agents," Swaminathan said. "Fi...Butterflies & the hormonal basis of interactions between life histories & morphology
...hat in the field the adaptation in life history to changing environments is not hampered by a hormonal mechanism that controls several traits. It further shows that the developmental system is flexible enough to allow evolution in directions opposing the correlation: phenotypes can change by genetic variation...Fire ant killing protozoa found in 120 Texas counties
...radicate the fire ants but it has the potential of changing it from a highly aggressive pest into one much less competitive with native species, said Dr. Forrest Mitchell, entomologist with the Texas Agricultural Experiment Station at Stephenville. Now that the survey is complete, the next step is to grow th...Kinase backgrounder: Iressa discovery part of major kinase project at Dana-Farber
...emical unit called a phosphate to another protein, changing its shape or altering its function. The Kinase Project now under way at Dana-Farber is focusing on tyrosine kinases, so named because they add the phosphate to tyrosine, an amino acid component of the protein. Many kinases, largely the tyrosine kinas...Ferr-D'amar wins 2004 Eli Lilly and Company Research Award
...is recognized for two vital breakthroughs that are changing the direction of research in structural biology and transforming microbiologists' understanding of how very large molecules function in living organisms. First, he developed new methods to make obtaining crystals of RNA much easier. RNA crystalliza...What it Takes: Design principles to broaden participation in SET
...entions to take hold, produce results and adapt to changing circumstances. Its components are proactive leadership, sufficient resources and steadfastness in the face of setbacks. The minimum conditions for assuring sustained commitment are continuity of funding and of support at the individual school and ...Study identifies which patients can benefit from targeted lung cancer drug and why
...of basic biological processes offers real hope in changing the course of cancer care and treatment."...Technique plucks rapidly evolving genes from a pathogen's genome
...hogen and incite an immune response. By constantly changing its antigen coat, a pathogen can elude the immune system, evolving eventually into a new strain to challenge the human immune system again. "The fact that we found most antigens were quickly evolving under our metric confirmed that our technique work...Biological oceanographers examine 'regime shifts' in complex marine ecosystems
...erfishing a species can also force a regime shift, changing the population dynamics of an entire ecosystem. A regime shift occurred at several levels of the food web in the English coinciding with lower phosphate levels. Other well-documented regime shifts have occurred in the northeast Pacific Ocean and in t...Scientists identify six genes associated with survival in diffuse large B cell lymphoma
... factors include but are not limitedto (1) rapidly changing technology and dependence on development of newproducts; (2) sales dependent on customers' capital spending policies andgovernment-sponsored research; (3) uncertainty of the availability ofintellectual property protection and the ability to protect t...Bye-bye Bio 101: Teach science the way you do science
...ny scientists and educators have actively resisted changing their teaching methods. Now, a group of persistent reformers is raising scientists' awareness of successful approaches to science teaching and providing them with tools to implement those strategies in their own classrooms and institutions. "There is......DNA methylation change in order to accommodate the changing patterns of gene expression. Now, for the first time, Drs Sun and Arceci provide in vivo evidence that the loss of PASG results in a reduced level of global genomic methylation and premature aging in mice. "In order to elucidate the function of PAS...Guiding gas exploration: U-M research offers inexpensive tool
...howing how important microbial processes may be in changing the fluid chemistry within the earth's crust," she said. ...How do animals exposed to 24-hour light retain their wake-sleep habits?
...an respond to unnatural light clues and adapt to a changing environment. This study is another step in the continuing research towards such comprehension.......lution allowed them to pick up the fine details of changing sodium concentration, particularly localized variations in the sodium gradient. First the team imaged a healthy rat kidney, showing, for the first time, the shape of the sodium gradient as it rises in a smooth slope from the outer...