Tag: "channel" at biology news
Researchers determine genetic cause of Timothy syndrome
...derstanding more about the nature of these calcium channel
defects could improve understanding of autism, whi...ll, that a pinpoint mutation in the CaV1.2 calcium channel
was the sole cause of Timothy syndrome. Keating collaborated on the studies with researchers from Ch...
Rare childhood genetic syndrome identified
...irs a very fundamental molecule a type of calcium channel
that is found in many tissues and organs. Calcium... at Children's Hospital Boston, likens the calcium channel
to a screen door. "After you go through the screen door, it automatically closes," he says. This mu...
Termites could hold the key to self-sufficient buildings
...ed network of tunnels and air conduits designed to channel
air flow for the control of internal air quality, temperature and moisture levels. Furthermore, the termites have evolved in such a way that they out source some biological functions, for example, digestive functions to a fungus that they farm inside...
Cell's gatekeeper for ammonia revealed in unprecedented detail
...rs publish the first atomic-level structure of the channel
that controls the passage of ammonia in and out of...d in greater detail than that of any cell membrane channel
yet described. The structure can help reveal the molecular basis of often life-threatening diseases ...
'Defensive' action by influenza viruses demonstrated by Hebrew university researcher
...rus by binding to and blocking a proton-conducting channel
which the virus needs in order to continue functio...es its own counteractions: either by narrowing its channel
to the extent that the blocking element in the drug is unable to bind and create a seal, or by widen...
Virginia Tech researchers to release findings on Smith River Project
...les that the tributaries play in defining the main channel
community. The Smith River Research Project principal investigators are Virginia Tech fisheries professors, Don Orth, Tammy Newcomb, Andy Dolloff, civil and environmental engineering professor Panayiotis Diplas, and project coordinator Colin Krau...
Heartless worms hold clues to cardiac arrhythmias, sudden death
...d to development of drugs that don't cause calcium channel
block The worm C. elegans seems an unlikely cand...o identify novel protein regulators of a potassium channel
involved in the rhythmic heartbeat. They report the success of their approach in the Aug. 10 issue o...
Nerve cells 'guided' to repair spinal damage: Technique
...earch Chair in Tissue Engineering. "A longitudinal channel
- a straight line - is the minimum distance between two points." The research, which has yet to be tested in animal models or humans, was funded by the Natural Sciences and Engineering Research Council of Canada and an Ontario Graduate Scholarship i...
LBP-1a gene mutation linked to disruption of normal fetal development
...ses containing blood from the mother. A sinus is a channel
inside certain tissues that contains blood. In the absence of this link to the mother's blood in the placenta, embryos suffered growth retardation by day 10 of pregnancy, and died the next day. The finding strongly suggests that LBP-1a plays a cri...
Bad news for pathogenic bacteria: Scientists find protein essential for bacterial survival
...Gpp stay bound to RNA polymerase. "The secondary channel
seems to be the hotspot for many interactions," Artsimovitch said. "It leads straight to the active site, and presents a confined area where many proteins and antibiotics that control transcription may bind to carry out their business." Knowing wha...
BioMed Central to consult funders and librarians over Open Access payment model
...ans and funding bodies: can mechanisms be found to channel
funding streams via the institution/library to pay... this consultation will allow us to explore how to channel
funds to pay for Open Access publishing in the future in a way that truly fits the needs of the com...
Commercialization deal boosts hope for new sickle-cell drug
...otassium and water exit the cell. Blockade of this channel
keeps the cells hydrated, resulting in much less sickling. The CHB researchers also discovered that clotrimazole has metabolites (breakdown products) that can reduce sickling without the liver toxicity and other side effects of the mother dru...
Wheelchairs biomechanics, prosthetic development
...ingle-wide platform ramps and caregivers preferred channel
ramps. Investigators found that ramps were delivered without instructions, moved during use, and were too narrow. These findings provide insight into the benefits and limitations of different ramp designs and implications for curb and vehicle access....
Epilepsy: Signals 'brake' in brain impaired
...meable for positively charged potassium ions. This channel
is mainly located at the signal inputs of a neutron, the dendrites, and has an important function there: it absorbs incoming excitant signals from other nerve cells. They 'trickle away', so to speak, through the many little 'potassium leaks'; on thei...
New pulmonary hypertension guideline challenges use of common medication
...ial hypertension (PAH) cautions the use of calcium channel
blockers, a commonly used treatment for high blood...mbers recommend against the empiric use of calcium channel
blockers or their use in patients who do not respond to acute pulmonary vasodilator testing, citing ...
Gene therapy alternative to calcium channel blockers
...ful gene therapy that mimics the action of calcium channel
blockers, agents widely used in the treatment of h... may lead to a gene therapy alternative to calcium channel
blockers and their sometimes severe side effects, but also further interest in the development of ge...
Bacteria spill their guts to aid researchers in quest for new antibiotics
...ure and function by monitoring and controlling the channel
as it opened and closed. They engineered a mutant ...stituted amino acid at different sites in the MscL channel
protein. When they added a chemical to the environment, the chemical bound to the amino acid, causin...
Endurance exercise found to be equally effective as diuretics in improving cardiac health
... (ACE) inhibitors and calcium antagonists (calcium channel
blockers) in preventing one or more major types of cardiovascular disease. The diuretics also tend to have fewer and less severe side effects, making it easier to stay on medication. In addition, the diuretics are relatively inexpensive. Exercise has...
Scientists call for better protection for coral reefs
...s are particularly threatened by sedimentationfrom channel
dredging, and other changes in nearshore water quality. The first four ISRS briefing papers will be presented at the10th International Coral Reef Symposium in Okinawa, Japan beginning June27. Dr. Kathleen Sullivan Sealey of the University of Miami w...
OUP launch a new Open Access Journal on Complementary and Alternative Medicine
...UCLA. "eCAM will provide the perfect communication channel
to help bridge the CAM gap between East and West, whilst at the same time insisting on the highest standards of scientific rigour. The combination of eCAM's TM free availability online with PubMed and Google indexing from the start will make eCAM r...
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