Scientists at Scripps discover a genetic cause for primary iron overload
...mingham (3) and his colleagues, including Beutler, characterizes the genes and symptoms of 23 African-American patients who have primary iron overload disease. This study found the same mutation in some of the patients, which supports Beutler's conclusion that this mutation is one of the causes of primary iron ove...Hope available for patients with anemia and myelodysplastic syndrome
... "These findings indicate that late-life anemia characterizes persons at risk for important clinical health outcomes," said Brenda W. Penninx, Ph.D., of the Wake Forest University, lead author of the study. "Health care professionals need to be aware of the clinical implications of anemia and begin to regularl...Researchers seek to clone 'mad cow disease' resistant cattle strain
... for the five to seven year incubation period that characterizes both the animal and human forms of the disorder. While scientists don't know how to stop the pathogenic process once it gets underway, some, like Eyestone and Huckle, are interested in creating an animal that lacks the genomic architecture to code fo...'Elves' makes protein crystallography easier
...ave given up working on. He hopes to find out what characterizes the nine out of 10 data sets that fail to produce good structural data. "I'm going through about six terabytes of data to look for patterns," Holton said. "I think that the basic problem is the crystal. If I can find a way to reliably establish whe......n cells, and causing the neurological wasting that characterizes the disease. Now, Williamson and his colleagues in the Department of Immunology at The Scripps Research Institute are telling another story. In an upcoming issue of the journal Science, Williamson and his colleagues present evidence t...Drug combo effective in advanced breast cancer
...gnals, interrupting the out-of-control growth that characterizes cancer. Slamon, director of Clinical/Translational Research at UCLA's Jonsson Cancer Center, said the two studies are important because, as Sledge said, they provide an example of how translational research is supposed to work. "This shows you can ac...Avastin-Tarceva combo provides 'one-two' punch against lung cancer
...f signals that prompt the runaway cell growth that characterizes cancers. Increased activity of the EGFr pathway, as well as increased number of tumor blood vessels resulting from VEGF expression, are associated with poorer outcomes for patients with NSCLC, the investigators note. Other research has suggested th...A gene that keeps species apart
... Drosophila. One of the more enduring definitions characterizes organisms as distinct reproductive units and species as groups of individuals that can interbreed and produce viable, fertile offspring. The lack of genetic exchange between species, called reproductive isolation, lies at the heart of this definition......s and lack the distinct apical-basal polarity that characterizes their epithelial counterparts. Both types of cells contribute to the body's function in distinct ways, with epithelium being the essential structural and physiological component of organs and tissues such as the kidney and the lining of the gut, and ......e out the function of the extremely long neck that characterizes some species of this group, including Tanystropheus longobardicus, which was discovered in the 1850s. About twice as long as its trunk, Tanystropheus' neck has 12 vertebrae along which extend elongated cervical ribs. Years ago, scientists concluded t...