Tag: "chemoprevention" at biology news

Green Tea Ingredient Can Kill Cancer Cells

...chemoprevention." The investigators feel that the chemoprevention properties of green tea need to be evaluated in human trials. Tea consumption in the world ranks second only to water consumption. Approximately 20 percent of tea consumed is green; the rest is black tea. Other authors on the paper are Nihal Ahmad,...

Aptosyn™ (exisulind) and other SAANDs target early event in cancer; AACR presentations detail novel apoptotic pathway

... also presented research suggesting Aptosyn™'s chemoprevention of precancerous colonic polyps in patients with FAP may be due in part to the drug's ability to restore downstream apoptotic signaling to a mutant APC pathway. FAP is caused by a defect in the APC gene that leads to a mutant form of the APC protein....

Supplement reduces risk of aflatoxin-related liver cancer

... Institute, are recognized leaders in the study of chemoprevention and phytochemicals such as chlorophyll, or dietary compounds and chemicals that may have the capacity to inhibit cancer....

Cancer-fighting drug may work in prevention and treatment

... still in clinical development for its broad-based chemoprevention activity, Oltipraz could turn out to be a doubly potent weapon against cancereither helping prevent it in high-risk people or shrinking cancerous tumors by depriving them of their blood supply. This wouldnt be the first time Oltipraz showed promise b...

M. D. Anderson receives one of its largest private research gifts

...earch in therapeutic agents, screening strategies, chemoprevention and diagnostic agents. Funding will help cover the costs of patient biopsies, laboratory tests and diagnostic images, research nurses and research data managers. These types of grants also could fund development of novel approaches for therapy or m...

Researchers identify first genomic blueprint of cancer preventive compound found in broccoli

...ve agent, which tells us how the process of cancer chemoprevention is occurring and provides us with a novel strategy for evaluating potential cancer preventive agents in future," explained Dr. Biswal. Dr. Biswal and his colleagues studied the gene profile of small intestines of mice to identify the genes regulated ...

Michael B. Sporn, M.D., to receive inaugural cancer prevention award

...o to someone who has been the stalwart soldier for chemoprevention for decades. The field of cancer prevention is ind...apers published in the early 1970s. His notion of chemoprevention challenged existing dogma of cancer therapy at the time, suggesting an approach other than the use o...

The role of obesity and calories in cancer prevention

...cer later in life; however, this is not an optimal chemoprevention method." The study, designed to identify potential dietary methods to alter pre-puberty estrogen levels, compared low fat (16 percent energy) or high fat (39 percent energy) diets composed of either omega-3 or n-6 polyunsaturated fatty acids (PUFAs) ...

Natural insecticide identified as potential cancer prevention agent for early stage lung cancer

...e apoptotic potential of NSCLC cells." The goal of chemoprevention for lung and other cancers is development of a specifically targeted agent with minimal toxicity that will delay, block or reverse cancer development. An estimated 169,400 new cases of lung cancer will be diagnosed in 2002, accounting for 13 perce...

Study provides direct evidence of the role of telomeres in prostate cancer development

...eful markers for assessing effectiveness in cancer chemoprevention studies," according to Alan Meeker, research fellow and lead investigator of the study which was conducted by researchers at the Brady Urological Institute and Department of Pathology, The Johns Hopkins University School of Medicine. "In addition, i...

Norwegian study demonstrates targeted coxibs may prevent oral cancer

... said that oral cancer was ideal for investigating chemoprevention because it was normally preceded by readily detect...vanced stages." He said that most approaches to chemoprevention have failed and this was probably because reliable identification of high-risk individuals had not b...

Over-the-counter pain relievers effective in protecting against breast cancer

...). Regular use of low-dose aspirin ( The goal of chemoprevention for breast and other cancers is to identify or develop specifically-targeted agents with minimal toxicity that will delay, block, or reverse cancer development. Early epidemiologic investigations have shown that NSAIDs potentially limit breast cance...

Cancer prevention pioneer receives AACR/Cancer Research and Prevention Foundation Award

...y of the first, definitive proofs of principle for chemoprevention came from the translational research by Dr. Hong a...ssibilities." When clinical trials suggested that chemoprevention wasn't potent enough alone to reverse more advanced pre-cancerous lesions, Dr. Hong created a new ap...

Scientists, physicians discuss latest discoveries for stopping cancer before it starts

...speak to the participants on the subject of cancer chemoprevention at the molecular level. The conference will open with a keynote address by Robert A. Weinberg, Ph.D. Dr. Weinberg is Professor of Biology at the Massachusetts Institute of Technology and the Daniel K. Ludwig and American Cancer Society Professor for ...

Scientists making advances in cancer prevention, detection and treatment to receive awards

...ontributions to basic and translational aspects of chemoprevention research. His lecture, "Protection Against Cancer: Edible Plants, Chemistry, and Gene Regulation," will take place from 3:15 to 4:00 p.m., Sunday, March 28, in Hall F-3. Titia de Lange, Ph.D., Leon Hess professor at The Rockefeller University in Ne...

Other highlights in the February 18 issue of JNCI

...es examined the cost-effectiveness of aspirin as a chemoprevention strategy for esophageal cancer in patients with Ba...tiveness and cost-effectiveness of aspirin for the chemoprevention of esophageal cancer in patients with Barrett's esophagus, Hur and colleagues found that aspirin the...

JCI table of contents, 15 March 2004

...icates that ODC inhibitors might be useful for the chemoprevention of BCCs. TITLE: Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/ mice AUTHOR CONTACT: Mohammad Athar Columbia Univer...

Fox Chase Cancer Center researchers identify significant smoking-induced genetic alteration

...ll biologist Margie L. Clapper, Ph.D., director of chemoprevention research at Fox Chase. In addition to Clapper, Meireles' co-authors include Fox Chase bioinformatician Radka Stoyanova, Ph.D., Bela Verma, M.S., a student at Robert Wood Johnson Medical School, and two investigators from the University of Kentucky, ...

Leader in cancer treatment and prevention research honored

...aboratory and clinical research has emphasized the chemoprevention and treatment of such pervasive and potentially de...reatment with chemopreventive agents. "Our cancer chemoprevention research laboratories are focused on research to uncover biochemical and molecular-based interventio...

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