Tag: "chromosome" at biology news

Fathers pass infertility to sons

...ion(ICSI). In each case, the fathers passed on a Y chromosome genetic defect calledan AZFc deletion. Such deleti...research inunderstanding the mechanisms by which Y chromosome deletions cause infertility,said Page. "We really don't know why this missing piece of the Y chromos...

Schizophrenia possibly linked to early brain development

...VCFS). This syndrome is tied to a gene deletion on chromosome 22. "Children with this syndrome have limb malformations affecting thedigits and some combination of minor craniofacial anomalies involving the eyes,nose and jaw," he said. "They also have a high frequency of early-onsetschizophrenia. And i...

Genome Research July tipsheet

...ced the Pas1locus to within 1.5 megabases on mouse chromosome 6. They also found that thedifferent susceptible ...ork suggests thatdeletions of unidentified TSGs on chromosome 12 cause most male germ celltumors, which commonly affect young men from 20-35 years of age. In the...

Mobile DNA sequences could be the cause of chromosomal mutations during the evolution of species

...en able to isolateand sequence the extremes of the chromosome 2 inversion which is found togetherwith the normal... all populations of the species. The comparisonof chromosome 2 with, and without the inversion, has allowed them to demonstratethat the inversion is generated by...

Scientists discover second gene for disorder described by Darwin

...egral part of thegroup that identified the gene on chromosome 2. Zonana, along with Dr. AlexMonreal and colleag...al dysplasia. Their group wasable to identify the chromosome 2 gene, named DL, with the help of "downless"mice. These animals derive their name from a sparsenes...

Ethnic clustering of male genes in India

...this social system onmale gene flow by comparing Y chromosome DNA from males of 10 different castesor tribes in ...dia. In particular, the researchers examined six Y chromosome markers, unique DNAsequences that can differ slightly between individuals; when any two males hadide...

Protecting the rice bowl: Chromosomal mapping of the rice blast fungus

...ng the first complete physical map of an M. grisea chromosome - animportant step towards defeating the depredati...ecisely order hundreds of clones spanningM. grisea chromosome 7. The striking success of their approach paves the wayfor mapping, and eventually sequencing, the ...

Gene protects tubby mouse strain from hearing loss

...ackson Laboratory and identified as a novel geneon chromosome 7. Dr. Nishina and her colleagues have fou...mosome 2 which is homologous tothe region on human chromosome 15 containing a gene for Bardet-Biedl syndrome inhumans. The obesity, insulin-resistance, and sensor...

Fragile X brain synapses mostly undeveloped, researchers say

... Fragile X refers to the brokenappearance of the X chromosome when cells are cultured under specificconditions. The new findings suggest possible roles of FMRP in dendritic spine maturationand pruning. "By studying an abnormal pattern of brain development, we havediscovered a process that is fundamental to norm...

Gene located for rare fat disorder

... gene for the disorder was found on thelong arm of chromosome 9, and studies are under way to isolate the gene.R...ipodystrophy - familial partial lipodystrophy - on chromosome 1. Other researchers in the study include UT Southwestern Center for Human Geneticscolleagues Ross W...

Cinderella's shoe holds 500 sequencing machines

...ice accurately and rapidlysequenced DNA from human chromosome 17 and demonstrates a bright future forconvenient, low-cost sequencing machines. Perhaps soon we can literally put asequencer in every pot....

Good seed, bad seed: Evolution divides the plant world

...electing genes from a limited region ofArabidopsis chromosome 1 and searching for their counterparts in the known ricesequence. They found that the rice genes they located in this manner werescattered over 10 of the 12 rice chromosomes, indicating that gene order is notpreserved between Arabidopsis and rice. ...

Researchers discover location of a testicular cancer gene

...newgenetic technique of their own invention called chromosome substitution, whereChromosome 19 in 129/Sv mice was replaced with the corresponding chromosome fromanother mouse strain. More than 80 percent of mice with the chromosome replacement hadsp...

Asthma-linked genes discovered at Berkeley lab

...tudies, was that one region ofthe human genome, on chromosome 5, tended to be inherited in individuals withasthma." Rubin's group has previously developed mouse models from a variety of humanconditions including Down syndrome, sickle cell disease, and atherosclerosis. For the asthma study, they eschewed the con...

FDA mandate for folic acid fortification may decrease the incidence of Down syndrome

... a genetic condition usually caused by an error in chromosome segregation in the mother's egg. Normal human cell...s, but Down syndrome cells contain three copies of chromosome 21 -- a condition known as trisomy 21. In the UnitedStates, trisomy 21 occurs in about 1 out every 1...

New University of Georgia study indicates possible ancient origin for retroviruses, the class to which HIV belongs

.... elegans, showing where each gene is located on a chromosome and itslikely function. McDonald and Bowen were thus able to use the C. elegans genomesequence to analyze the entire complement of retrotransposons in the worm'sgenome. "We analyzed a class of elements called long terminal repeatretrotranspon...

A safer way of altering genes

MICE engineered to carry an extra artificial chromosome have successfully passedit to their offspring. Alt...n biotechnology. "It's thefirst time an artificial chromosome has ever been shown to be inherited in anymammal," says Eileen Utterson, vice-president of corporate...

Tracing the evolution of sex chromosomes

...velop into females, whileembryos with an X and a Y chromosome develop into males. The rationale behind this ar...port that they havereconstructed the stages of sex chromosome evolution and the time course overwhich these chromosomes were built. This research provides a glim...

The evolution of the sex chromosomes: step by step

...ern X and Y chromosomes. Many genes on the human Y chromosome have homologues (analogous genes) on the Xchromoso... a male. "The SRY -bearingchromosome became the Y chromosome and its SRY -deficient partner becamethe X chromosome," says Lahn. Over time, X and Y stopped recom...

New evidence pushes back age of sex-determining chromosomes

...inversion and shuffling of regions of DNA on the Y chromosome so that they couldno longer line up with analogous regions of DNA on the X chromosome partner.This prevented DNA exchange between the similar regions of the two sexchromosomes, and made ...

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