Strep disrupts blood clotting to infect humans
...selves to move more freely around the human host's circulatory system. The molecule is so specific, it only works on humans, not on other animals. "The theory is that, as bacteria cause a local infection and begin to grow, the clotting system produces clots in the blood vessels around the infection, closing th...Plumbing trees' plumbing reveals their engineering skill
...s the most exacting root-to-twig physical of their circulatory system yet. The scientists' findings reveal the impressive adaptive engineering of deep-rooted trees in adjusting the size and structure of their piping, or xylem, to maximize water uptake, maintain their integrity and avoid flow-blocking embolisms. ...Fundamental change to Immunology 101
...lly imports marrow T-cell progenitor cells via the circulatory system. The cell types that travel from the marrow to the thymus were not exclusively pinned down, but researchers have suggested HSCs themselves, multipotent progenitor (MPPs) cells, or a common lymphoid progenitor (CLP) cell from the marrow itself,...Newly designed nanoparticle quantum dots simultaneously target and image prostate tumors in mice
... glycol). They injected the quantum dots into the circulatory system of the mice first to test "passive" targeti...they injected the conjugated quantum dots into the circulatory system of the mice, the dots selectively accumulated at the site of the tumor through binding to the...'Cardiofunk' mutation: Probable source of congenital heart defects
...e contracts, blood flows forward into the embryo's circulatory system instead of backward into the atrium. But in the mutants, blood flowed back and forth between the atrium and ventricle, never leaving the heart. The researchers expected the mutation responsible for the valve defect would be in a gene expressed...Protein-centric drug development and functional glycomics enrich biopharmaceuticals pipeline
...two additional carbohydrate groups that can extend circulatory half-life and magnify efficiencies. Active research on glycosyltransferases to understand the role of carbohydrate interactions in a cancerous cell is also likely to provide further opportunities for application of glycomics. One such prospect li...University of Pittsburgh receives NIH funding to develop heart assist device for infants
... primary objective is to develop a highly reliable circulatory assist device for infants who would otherwise peri...o must be designed to meet the special medical and circulatory needs of infants with complex congenital heart disease," noted Bradley B. Keller, M.D., professor of...BioTime awarded NIH grant to aid Hetacool development
...tient may be maintained in hypothermic cardiac and circulatory arrest during surgery. In the research project, th...mplex surgical procedures that require cardiac and circulatory arrest. This research also may lead to uses of HetaCool in hypothermic emergency medical procedures ...New approach offers potential drug-discovery shortcut
...ock, which prevents the correct development of the circulatory system in the lower portion of the body. A panel of these embryos was exposed to a very diverse library of small molecules 5,000 in all to see if any would prevent expression of the gridlock mutation. Two similar molecules were identified that su......esoderm becomes muscle, bone, cartilage, heart and circulatory system, and the urinary and genital system, including kidneys. Mauch's study used the new method to illuminate sites within a 36-hour-old chicken embryo where any of three genes were active: chordin, indicated by fluorescent blue; paraxis, lab...Cells' ability to open blood's floodgates hinges on unexpected factors
...atedly or a nerve cell increases its activity, the circulatory system responds by increasing blood flow to the activated cells. They assumed this happens so the blood can supply the cells with more sugar and oxygen as fuel for the increased workload. Over the past decade, a growing body of evidence has suggested...New book explains plants, medicine
... treatments have been associated with instances of circulatory collapse, respiratory arrest and nerve irregularities. Blossoms of germander in herbal teas or capsules to treat obesity have been shown to cause acute hepatitis. Instances of kidney failure have been found in Japan, China and the United Kingdom in p...Close interaction seen between blood vessel development and fat tissue formation
...new organs and tissues, since the development of a circulatory system is a key challenge in the field of tissue engineering. Fukumura, Duda and Ushiyama who is now with the National Institute of Public Health in Tokyo are co-first authors of the Circulation Research paper; other co-authors are Lei Xu, MD, PhD...Canada, US launch collaborative research programs for circulatory and respiratory health
...ers in their fields to unravel the complexities of circulatory and respiratory illness. I am very hopeful that this is the first of many collaborative efforts between our two institutes," said Dr. Bruce McManus, ICRH Scientific Director. "We are also pleased to have the support of other Canadian partners in this...New prospects for treating muscular dystrophy: Stem cells restore muscle in MD mice
...to all of the muscles. If you could go through the circulatory system, you would have a way to homogeneously deliver the cells or the vector to all the muscle fibers," he said. Several key issues must be answered before such a therapy can be developed for humans, according to the Science authors. First, these...Nanotech strategy could create new organs
...anch out in a pattern, similar to that seen in the circulatory system, to provide oxygen and nutrients to liver or kidney cells that have been cultured in a lab. Using new fractal computational models, the network is designed and etched onto silicon surfaces which are then used as molds to transfer the pattern...Scientists discover key gene in artery formation
...ed by genetic signals. It was always thought that circulatory flow and pressure caused a blood vessel to be an artery or a vein. But our work, along with studies in mouse, demonstrates that this identification step is crucial for normal blood vessel formation." This work by Dr. Lawson and colleagues in Brant W...Study of thyroxine transporter molecule shows how key hormone hitches a lift round body
...te drugs." HSA is the most abundant protein in the circulatory system. Its principal function is to transport fatty acids, but it is also one of three proteins that delivers thyroxine. Levels of thyroxine circulating in the body are used as a biochemical indicator to help gauge how active the thyroid gland is. ...In some patients with chronic fatigue syndrome, left ventricular function may be involved
... well as abnormalities in neurohormonal systems of circulatory control. Other studies have found that CFS patients may have reduced blood flow in exercising muscles. A New Study The main symptom of the CFS patient (i.e., chronic fatigue that is greatly exacerbated by even minor effort) is similar to that of ...Fabricated microvascular networks could create compact fluidic factories
...g functionality, "providing an analog to the human circulatory system for the next generation of autonomous heali...echnology. "The embedded network would serve as a circulatory system for the continuous transport of repair chemicals to sites of damage within the material." The...