Tag: "clamping" at biology news
'Smart gene therapy' protects against damage from heart attack
...ey restricted blood flow to the animals' organs by clamping
key arteries for a period of an hour and then examining the organs for evidence of injury. Inducing ischemia and oxygen deprivation in this way caused a five-fold increase in the gene's activity in the heart, the researchers reported. That activity, ...
Clamping down on a cancer-causing protein
...the normal form of Abl, or preventing the cap from clamping
onto the proper parts of the molecule, the switch gets frozen. This explains why several roads might lead to the same result cancer. Even if the cap structure is present, other molecules might interfere with it and break the internal switch. By show...
Unique study reveals new details on how genes are transcribed
...ly takes place. RNAP transcribes a gene by tightly clamping
itself to the DNA and elongating-growing out-over the gene's base-pairs, catalyzing the creation of an mRNA template in the process. Previous studies have shown that this elongational growth/transcription is discontinuous; the RNAP may pause at vari...