Computer model offers new tool to probe Woburn toxic waste site
...lines, including law and medicine. Students in the class learn about childhood leukemia and its treatment, groundwater flow, water chemistry, and contaminant plume movement. They then become expert witnesses in a mock trial -- training that will come in handy should they ever need to use their knowledge of...World's most alkaline life forms found near Chicago
...e dominant microbes belonged to the Proteobacteria class including a large number from the Comamonadacea family of the beta subclass. "In high-pH microcosms experiments, one of these microbes is closely related to a hydrogen oxidizer," said Roadcap. That means the bacteria exploits the hydrogen given off ...Activity detailed for sirtuins, involved in metabolism, aging, gene expression
...ld represent early steps toward developing a novel class of drugs that might promote health in various ways. Now, structural biologists at The Wistar Institute studying the role of sirtuins in gene expression specifically in turning genes off report new findings that significantly illuminate how sirtuins...Fruits offer powerful protection from skin cancer
...such as orange peel. Evidence has shown that this class can inhibit the growth of many cancers and pre-cancerous lesions by helping rid the body of cancer-causing chemicals or by interfering with signals that cause rapid cell division. Researchers in this study determined that the compound maintains its ...New model of Alzheimer's enzyme may help refine future treatments
...s study suggests that gamma-secretase belongs to a class of enzymes where, in addition to the active site (which is in limited supply and therefore leads to competition between APP and Notch), there also are "binding" sites, where molecules can latch onto the enzyme without competing with each other and wi...Cumbre Inc. and collaborator publish on a novel bacterial RNA polymerase inhibitor
... October 24, 2003 issue of Science entitled "A new class of bacterial RNA polymerase inhibitor affects nucl...ication and characterization of the novel "CBR703" class of inhibitors through combined efforts in biochemistry, genetics and structural modeling with contri...New class of antibiotics stops pathogens in their genetic tracks
... Ohio Researchers have found that a promising new class of antibacterial chemicals inhibits one of the mos...ibiotics. Like many bacterial inhibitors, this new class of compounds called the CBR703 series inhibits RNA polymerase, the key enzyme in gene expression. ...Saliva spits out information on chemical exposure
... accidents or even acts of war and terrorism. "The class of pesticides we are studying, organophosphates, are chemically similar and work on the same general principal as nerve gas," said Charles Timchalk, a Battelle toxicologist at PNNL. "Both pesticides and nerve gases inhibit an enzyme called acetylchol...New protein provides clue to diabetes
...istance." Key to this are glucose transporters, a class of proteins that shuttles glucose molecules through the membrane and into the body of the cell. The first glucose transporter was discovered in 1985 in Lodish's lab. Several others, including GLUT4, have been discovered since then. While most glucose...New scheduling method raises efficiency of electronics recycling
...ch may open up an area of research for a whole new class of scheduling problems." Findings about the new approach are detailed in a paper appearing this month in the IEEE Transactions on Electronics Packaging Manufacturing, published by the Institute of Electrical and Electronics Engineers. Scheduling is a...... and Research Center have discovered that a single class of molecules serves as the immune system's gatekeeper in the lungs, damping the immune response in some situations and promoting it in others. The findings, published in the October 3 issue of the journal Cell, resolve an apparent paradox that preve...The DFG announces EURYI Awards for Germany
...ents and demonstrate the potential to become world class leaders in the respective research area. Due to the differing ages when a doctorate may be awarded in the various European countries, there is no age limit. Rather, applicants should have between two and up to ten years of postdoctoral research expe...Discovery may be first plant cell surface molecule that halts cell proliferation
...ics, were the first to independently discover this class of proteins nearly eight years ago. Dohlman found the first such protein in yeast, while Siderovski had found similar proteins in humans. Jones, who for many years has been studying the plant components equivalent to the G protein complex in mammals,...JCI Table of Contents, September 15, 2003
...pment, migration, and functional activation of one class of such T cells (CD4 T cells) have been limited. T..., Massachusetts, have created fully functional MHC class II molecules for tetramer-based analysis of T cell populations. Using these MHC class II tetramers ...National lab trains U. S. customs agents against WMD
...ne of Defense program sponsors the training. "Our class is designed to supplement training the Bureau of Customs and Border Protection already provides its inspectors. The NNSA-sponsored training has become even more important in light of the growing need to protect against weapons of mass destruction co...Experimental cancer drugs may halt events that lead to cardiac hypertrophy and heart failure
...topped by histone deacetylase (HDAC) inhibitors, a class of therapeutic agents currently under development as cancer drugs, according to researchers at the University of Pennsylvania School of Medicine. Cardiac hypertrophy is one of the leading causes of congestive heart failure, the most common diagnosis...Diabetes drug may be new tool in treating breast cancer
...r have decoded the step-by-step process by which a class of popular anti-diabetes drugs inhibits cancerous tumor growth. With the discovery of this molecular chain of events, as reported in the September 2003 issue of Molecular and Cellular Biology, the Georgetown researchers are now studying whether the...Lasker Award honors Rockefeller University biochemist for pioneering studies of gene activation
...leagues have discovered several members of another class of regulatory proteins, called coactivators, that represent a third level of transcriptional regulation in addition to the basal transcription machinery (polymerases and general transcription factors) and the DNA-binding regulatory factors (activator...Potent toxin reveals new antibiotic resistance mechanism
...cancer agent known as an enediyne. Enediynes are a class of anti-tumor antibiotics that work by shredding DNA and disrupting the ability of a cell - such as cancer cell or a unicellular organism like a bacterium - to function and reproduce. They rank among the most potent naturally occurring antibiotics, a...New chemical process can separate, manipulate carbon nanotubes
...urnal Science. "In addition to presenting a broad class of materials, nanotubes tend to stick together and form bundles, making it even more difficult to separate and use them." Several years ago, Strano and co-workers at Rice developed a technique for breaking up the bundles and dispersing the nanotubes ...