Tag: "class" at biology news

Fe-TAML(R) activators developed at Carnegie Mellon break down toxic pesticides

...own some organophosphorus compounds, a widely used class of agricultural pesticides associated with profoun...mperature. These chemicals belong to another major class of compounds, chlorophenols, which are found in pesticides, disinfectants, wood preservatives and ot...

New pollutant cleanup technique puzzles, pleases chemists

...ctoral fellow in Meyer's lab, are organohalides, a class of compounds used in pesticides, pharmaceuticals, ...ntal Protection Agency report. Organohalides are a class of organic compounds that include a halogen, a group of elements comprised of bromine, fluorine, iod...

Natural fat compound may be basis for new class of drugs targeting obesity

...ating a discovery that may be the basis for a new class of drugs targeting obesity and other eating disord...ful drug development. This gives us hope for a new class of anti-obesity drugs based on natural chemicals." To test the role of OEA and its receptors, Jin Fu...

JCI Table of Contents

... studies have implicated CD1d, a non-classical MHC class Ilike molecule prominently expressed on intestinal epithelial cells, in the regulation of intestinal intraepithelial lymphocyte activity. Blumberg et al. examined whether CD1d expression could be regulated by intestinal luminal contents using colon-d...

Study seeks genetic keys to exercise success

...xercise for Health and Fitness, a three-day-a-week class that involves 30 minutes of aerobic exercise each ...on of the 30-week study requires enrollment in the class in the spring semester as well. Any volunteer is free to withdraw from the research study at any ti...

New clinical study uncovers mechanism by which chromium picolinate may enhance insulin sensitivity

...etes who were treated with either sulfonylureas (a class of diabetic drugs that increase insulin secretion), or a diet program. Both groups were randomized to receive either chromium picolinate (1000 mcg) daily or placebo. The most accurate measure of insulin sensitivity, hyperinsulinemic, euglycemic cla...

JCI Table of Contents, 15 August 2003

...been processed and presented on the surface of MHC class II molecules. This presentation process requires t...ases such as the cathepsins, which degrade the MHC class II chaperone invariant chain to generate class IIassociated invariant chain peptides. Eva Tolosa and...

Lipids get the spotlight in new NIGMS 'Glue Grant'

...tor of the Lipid MAPS Consortium. For example, one class of lipids, the sterols, includes the hormones estrogen and testosterone which promote our gender-linked physical traits. The Lipid MAPS Consortium is divided into six focus areas. The "lipidomics" focus area will investigate six major groupings of l...

Researchers identify new cause of genomic instability

...cers could be highly significant, said Alt. Such a class of mutation would not have been readily detected in most searches for genes that suppress tumors in humans. Indeed, Bassing discovered that tumors in these mice still had a functioning H2AX gene. "A major question is why haploinsufficiency of the H...

From studies of a rare human mutation to new approaches to herbicides or antibiotics

...lant or bacterial forms of PBGS, providing a novel class of herbicides or antibacterial agents useful in areas as far-flung as treatment of patients or prevention of bacterial infection of specific crops. Jaffe's co-authors include postdoctoral associate Sabine Breinig, Ph.D., and scientific technician Lin...

A new twist on DNA

...lity to measure molecular torque will enable a new class of experiments to study the mechanical behavior of protein enzymes that interact with the DNA molecule. For example, Bustamante and his colleagues are now using the same experimental apparatus to explore how the enzyme DNA polymerase -- which copies ...

Mutation may help cause acute myeloid leukemia

...indicate that tyrosine kinases may be an important class of cancer-causing genes in leukemia," says principal investigator Michael H. Tomasson, M.D., assistant professor of genetics and of medicine. "It further suggests that drugs designed to inhibit these molecules might provide effective new treatments f...

Researchers solve structure of key drug target

... widely prescribed drugs. The protein belongs to a class of molecules called membrane transport proteins whose primary job is to move molecules as diverse as nutrients and neurotransmitters across the cell membrane. Membrane transport proteins play such a vital role in the cell that their disruption is tho...

Fears of second-hand smoke confirmed

... cigarette smoke underlines the importance of this class of molecules in the treatment of tobacco smoke-induced pulmonary diseases....

New compound class found to trigger changes in cell garbage can

Researchers have discovered a novel class of compounds that affects the cell's garbage dispo...lleagues found these compounds constituted a new class of inhibitor that changes the shape of the proteasome. "This is a completely different class of pro...

Portuguese teacher gets hands-on look at cutting-edge research at EMBL, Germany

...ng the best ways to integrate what I learned in my class activities next year," notes Maria Goretti, who teaches chemistry and physics to high school students at Escola Secundria Reynaldo dos Santos in Vila Franca de Xira in the south of Portugal. "The focus on biology was not an obstacle for me as the bor...

Gene more than doubles risk of depression following life stresses

...lf between cells. Since the most widely prescribed class of antidepressants act by blocking this transporter protein, the gene has been a prime suspect in mood and anxiety disorders. Yet, its link to depression eluded detection in eight previous studies. "We found the connection only because we looked at ...

Emory scientists find anti-tumor compounds in magnolia cones

... in mice. Researchers have been interested in this class of compounds, called angiogenesis inhibitors, for the last several years, and clinical trials are just now assessing their effectiveness against various kinds of cancer. The team's research was published in the Journal of Biological Chemistry online ...

Searching for the 'real' waterworld

... d'Astrophysique Spatiale, France, described a new class of planets that could be awaiting discovery: 'waterworlds'. According to Lger and his colleagues, these waterworlds would contain about six times the mass of Earth, in a sphere twice as wide as our planet. They would possess atmospheres and orbit th...

Melbourne scientist overturns 30 year calcium dogma

...cuss the latest on their recent discovery of a new class of protein that they have linked to breast cancer and fertility. Hubbard, a trained dentist and bio-medical researcher, is using proteomics to investigate the role of calcium and cell survival. When beginning this research, he knew that dental ename...

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