Researchers identify key pathway in the pupils response to light
...leus, which is where the body's internal circadian clock is located. As a result, Van Gelder believes these...ay an important role in synchronizing the internal clock to external light cycles, and probably are essential to tasks such as recovery from jet lag or adapt...Molecule helps pupils respond to light
...land secretion. In mammals, the internal circadian clock resides in the brain, and sunlight is the cue that resets this clock daily. Improved understanding of the circadian system could lead to better treatments for jet lag an...Purdue researchers discover basis for biological clock
WEST LAFAYETTE, Ind. -- The biological clock -- timekeeper for virtually every activity within ...stand the complex chain of events that connect the clock to events in the body," said James Morr, Dow Distinguished Professor of Medicinal Chemistry in Purdu...Science's top ten: Discovery of genes' 'control switches' named top advance of 2002
...wired to the very area of the brain where the body clock resides, and contain a pigment called melanopsin. Two studies this month confirmed that melanopsin responds chemically to light, though other compounds may be involved. Sharpened View of Space: New technology erased the blurring effect of Earth's a...Mouse gene knockout illuminates how light resets clock
... contributor" to circadian function.** Each day, a clock in the brain's hypothalamus that governs daily rhy...rks has been a mystery. Light can still reset the clock even if the rods and cones, the photoreceptors in the retina for vision, are removed, but not if the...Scientists shed new light on the body's internal clock
As mammals, our internal (circadian) clock is regulated by the patterns of light and dark we ...tion is transmitted from the eye to the biological clock in the brain has been a matter of scientific debate. Scientists had suspected that a molecule called...Gene responsible for rewinding body's 'clock' described by scientists at TSRI
..., understanding the protein that resets the body's clock should help in research aimed at countering the mo...ave provided evidence of the existence of internal clock mechanisms by placing organisms in chambers isolated from day/night cycles. In spite of this, their ...Even green pond scum can suffer from jet lag
...cessfully determined the structure of a biological clock protein for the first time. The protein in questio...sic biological processes. When a person's internal clock is out of sync with the environment, jet lag is the result. Not many scientists are studying biologi...Researchers find genes connected to seasonal reproductive clock in hamsters
...fied three genes that are involved in the seasonal clock that determines when hamsters...or off as part of an internal clock in hamsters. These genes help regulate levels of thyroid hormones in the hypoth...Research reveals a cellular basis for a male biological clock
...ected: Men, as well as women, have a reproductive clock that ticks down with age. A recent study revealed that sperm in men older than 35 showed more DNA damage than that of men in the younger age group. In addition, the older men's bodies appeared less efficient at eliminating the damaged cells, which ...UT Southwestern scientist helps identify gene that may lead to treatments for sleep disorders
...vital component in the regulation of the circadian clock the brain's day-night mechanism that allows human...ropriate time of day. "Slimb is one of the newest clock genes being identified, and we believe it is also involved in human clock regulation," said Jiang, c...UT Southwestern postdoctoral researcher wins international Young Scientist Prize
..." module that is involved in regulating the body's clock appears in the Nov. 22 issue of Science. "As a scientist and researcher, I was impressed with Jared Rutter's study of the circadian rhythms. In fact, all of the winning entries this year really make a researcher, no matter the years of experience, si...Clock cues: Cellular sensing, metabolism research wins Amersham Biosciences and Science Prize
...on monoxide affects NPAS2's ability to bind with a clock protein called BMAL1, which in turn affects the expression of certain circadian cycle genes. But one PAS wasn't enough: Rutter also took on the challenge of uncovering the biological role for an enzyme called PAS kinase. After extensive studies of th...Researchers create DNA 'nanocircles' to probe the mystery of aging in human cells
...omeres in the test tube. "The telomere is the time clock that tells a cell how long it can divide before it dies," Kool noted. "The consensus is that the length of the telomere helps determine how long a cell population will live, so if you can make telomeres longer, you could have some real biological eff...Cellular pathway includes a 'clock' that steers gene activity
...ng it," he said. "The pathway was operating like a clock with a pendulum, delivering the signal at particular intervals of time in a way that could resonate with the behavior of the genes in the nucleus." When information moves through a cell pathway to genes in the nucleus, it prompts the genes to send ou...Scientists at the Scripps Research Institute discover how a plant times its flowering cycle
...expression levels that follow the solar day. These clock genes ebb and flow throughout the day and year as they are needed, and comprise a complicated set of feedback switch "clockworks" that turn on and off other genes as needed. For instance, plants use two photoreceptor proteins--the blue light photorec...Gene controls plant's clock and flowering time
...ower and is critical for keeping a plant's 24-hour clock running accurately. The researchers will publish t...difficult to separate that from its effects on the clock that determines plant rhythms," says Doyle, a research assistant in the College of Agricultural and ...Dartmouth researchers identify multi-tasking circadian protein
... frequency encodes a central cog of the biological clock and that light resets the clock through frequency. He then determined that the clock proteins White Collar-1 and White Collar-2 bind...40-year search is over: UT Southwestern researchers identify key photoreceptor in fungi
... identified WC-1's role in the internal biological clock of fungi, which is called the circadian clock and is controlled by light. This internal time-keeping system is a fundamental property in almost al...New way found to see light through novel protein identified by Dartmouth geneticists
...absorbed by a molecule that is actually within the clock and is an activating element in the clock cycle. This is a new molecular mechanism to see light and a new way for light to have an effect. Alt...