Large Gene Study Questions Cambrian Explosion
... birds and mammals about310 million years ago. "A clock isn't any good unless it is calibrated to atime that everyone else agrees on," Hedges explains, "and just about everyoneagrees on the date when reptilian ancestors of birds and mammals appearedbecause it is based on well-accepted studies of fossils."...Researchers Discover Mechanism That Drives Daily Body Rhythms
... machinery that controlsthe inner movements of the clock may drive the basic rhythms of the body -- therise...is, how a bodily rhythm iscontrolled from the core clock loop," says Steven Reppert, professor ofpediatrics at MGH and Harvard Medical School. Xiaowei Jin an...Immortalizing Enzyme Does Not Make Human Cells Cancerous
...ack to the tips of chromosomes - is the biological clock that governs howmany divisions a cell will go through. With the new findings, the way now seems clear for research into newtherapies for age-related diseases and for cancer - two ends of the samespectrum. The scientists emphasize, however, that ...Science Announces Top Ten Research Advances Of 1998
... on how the molecular "gears" driving thecircadian clock respond to light and temperature cues and how they work togetherin different organisms. The results showed a surprising commonality betweenclock workings in organisms from bacteria to humans. What's more, it appearsthat fruit flies and mice-separated...International Genome Team Deciphers Genetic Instructions For A Complete Animal
...e, a few dozensequencing machines hummed round the clock and most days of the week. The firstshift arrived at the lab at 5:30 am, according to Waterston, to unload theprevious night's run. The last shift, which left the lab at around midnight,kept the machines whirring until dawn. In all, 2 million "rea...Study Associates Asteroid Or Comet Impact With Extinctions In Argentina
...al time clocks," saidSchultz. "We compared a clock in the glass to a clock in the soil to a clock inthe deep-sea cores. This told us the conditions at the time. We weres...Shedding Light On Circadian Rhythms
...living creature. In mammals,the internal circadian clock resides in the brain, and sunlight is the cue thatrewinds this clock daily. Researchers have now found a biochemical pathway thatsenses blue light, and thereby connects ...Two Brandeis Scientists Shed Light On The First Photoreceptor Known To Set Circadian Rhythms
...iological clocks. "A functional biological clock has three components: input from theoutside world ...anism itself, and geneticmachinery that allows the clock to regulate expression of a variety of genes,"says Hall, a professor of biology. "We now have a pret...Glowing Cyanobacteria Gives Researchers New Clues To Circadian Rhythms
...tivity ofanother gene that they knew the circadian clock controlled. Whenever thecircadian clock was working, the cell made bioluminescent proteinsrhythmically-causing the cell to glow with a predi......ts to people. In humans, delayed resetting by the clock is an underlying cause of jet lag, and clock malfunction has been linked to seasonal affective disorder and various sleep and mental disorders. ...First Reproducible Cloning Of Mammals From Adult Cells Reported In Nature
...ir genetic instructions. "We had to turn back the clock of an adult cell so that it behaveslike a newly fertilized embryo, which would develop into a normal adult,"says co-author Anthony Perry, Ph.D., a postdoctoral researcher in Dr.Yanagimachi'slaboratory. Within five minutes of the donor nucleus remova...Scientists Identify New Gene That Controls Sleep/Wake Cycle
... begin to makeRNA again by midday. The pace of the clock is set by a time lag: while the per and tim genes... co-authors on the second paper, "The Drosophila clock gene double-timeis a protein closely related to human casein kinase I e ," are Kloss, LinoSaez, Ph.D...Researchers Identify New Component Of Circadian Clock
...gene known to be an integral part of the molecular clock offlies. Researchers have also identified mammalia...n version of per, whichis likely to be part of the clock based on its similarity to the fly gene," saysWeitz. In a related paper in the same issue of...Researchers Show Mechanism And Similarities Of Biological Clocks
...one team describes the working partsthat drive the clock in mice forward like a watch spring, and in anothe...ne. "We now have three different circadian clock genes that are conservedbetween insects and mammals," Takahashi said. "These genes define a surprisi...Does Mountain Living Slow Rate Of Molecular Evolution?
... slower the molecular clock ticks. Wh...e slower the clock ticks. All of this makes a more interesting soup than DNA simp...Tiny Jamaican Tree Crab Made Big And Fast Evolutionary Leap, Scientists Discover
...uld use thechanges like the ticking of a molecular clock to trace the history of eachspecies back to its or...plains. The scientists calibrated this molecular clock to an evolutionary event wellestablished by geological studies, the closing of the Panama land bridg...Scientists Discover Proteins Which Help Set The Body's Clock
...nd in the skin, they could behelping set the daily clock from sites in skin cells. This idea agrees with arecent study which showed circadian rhythms can be set by shining light behindthe knees. CRY 1 and 2, which respond to the blue-white region of the sunlightspectrum, are only the second set of li...Gene Study Shows Mammals Lived Before Extinction Of The Dinosaurs
...ar and Hedges used like the ticking of a molecular clock to tracethe history of each species back to its or... as soon as a newspecies evolves, so the molecular clock takes you back to the actual time oforigin." The researchers found that their molecular clock yiel...MIT Biologists Identify Aging Mechanism
...to the ERCs' role in yeast cell mortality. "Setthe clock early and the alarm rings early." An artic... Professor Guarente inquired above, could "set the clock early (so) thealarm rings early"? Their experimental results suggest a paradox. The formation of ERC......anges in the light/dark cycle. In each appendage, clock genes turned on and off in unison, according to rh...ntists hope that understanding the location of the clock tissues and cells, as well as identifying which genes and proteins make up the biological cogs, will...