Transporter's function provides support for eating vegetables, limiting antibiotics
... of the National Academy of Sciences that they had cloned the SLC5A8 transporter from the human colon. While...gan to fall together. Dr. Ganapathy's lab actually cloned SLC5A8 from a mouse kidney three years earlier. He knew it was a transporter, but when he looked for...Schering-Plough scientists identify protein essential for cholesterol absorption from intestine
...tist, Cardiovascular/Metabolic Discovery Research, cloned the NPC1L1 gene and characterized its expression. Employing immunohistochemistry they showed that the NPC1L1 protein is specifically located on the brush border membranes of jejunal enterocytes, the side of the cell that comes in direct contact with...Most clones doomed from the start, according to Temple University embryologist
...il scientists can improve the early development of cloned embryos, cloning will remain marginally successful...of Science (AAAS). Currently, only 1-5 percent of cloned embryos succeed, and many that do succeed are unhealthy. Keith Latham, Ph.D., Associate Professor o...Mice cloned from olfactory cells
Researchers have successfully cloned a mouse using mature olfactory neurons as the gene...ns following transfer into the oocyte. Because the cloned animals are normal, our experiment also shows that [some] brain functions do not involve genetic alt...Equine cloning's triple play sheds light on calcium, cell signaling, human disease
...increasing calcium levels in the fluid surrounding cloned equine embryos proved the key to equine cloning. W... Pioneer and July 27 of Idaho Star, two more mules cloned from the same fetal mule skin cell line, added to the success of the University of Idaho-Utah State ...Advances in equine cloning may aid insight into human diseases
SEATTLE, WA On May 4, 2003, scientists cloned the first mule, an animal otherwise unable to repr...of equine clones as opposed to the health of other cloned animals, asserting that "mules bridge the gap of science" since they are usually born sterile. AAAS ...Human embryonic stem cells may promise medical advances
...y capable of becoming any cell in the body, from a cloned human blastocyst. The stem cells were harvested fr...stem cells from the resulting cell mass inside the cloned blastocysts. In theory: "Because these cells carry the nuclear genome of the individual, after diffe...2004 AAAS annual meeting spotlights world health, oceans and family science
...Research or "therapeutic" cloning technologies and cloned animals -- including a trio of cloned mules in the exhibition hall Sunday, 15 February -- are likely to generate interest at the AAAS Meet...Researchers seek to clone 'mad cow disease' resistant cattle strain
...entist for PPL Therapeutics, the organization that cloned Dolly the sheep, now heads the VMRCVM's transgenic...reate Dolly the sheep and Mr. Jefferson, the first cloned calf. Basically, the process involves taking somatic cells harvested from an animal, and replacing t...A big surprise: Young nerve cells can rewind their developmental clocks
... of Merck & Co. and one of the study's co-authors, cloned the Foxg1 gene while he was working at Memorial Sloan-Kettering Cancer Center in New York. He also did seminal work in the late 1990s showing that when the gene is eliminated in embryonic mice, the brain's cerebral hemispheres barely develop. Subseq...Mouse embryonic germ cells and male gametes created in the lab
...responsible for many of the abnormalities found in cloned animals. Reprogramming cells Embryonic germ cells may also aid in understanding the process of cell specialization. Most of an embryo's cells - and all adult cells - are programmed to specialize and create particular tissues and body parts via a s...Novel approaches to current cellular therapies continue progress toward disease prevention
...nother unrelated donor cow. This therapeutically cloned embryo was grown in vitro to the blastocyst stage ...f peripheral blood leukocytes that originated from cloned donor cells, peaking at nine to 17 percent in the granulocytes, and at lower levels in lymphocyte su...Newly identified genes may help predict outcome in childhood leukemia
...ome Predictor in Acute Leukemia 1), a novel, fully cloned human gene, and additional newly identified genes,...sociated with better outcomes. As the group fully cloned and characterized the G0 expressed sequence tag, it was given the new name of OPAL1. ...Genetic info of cloned pigs may help babies before birth
The birth of the first cloned animals in North Carolina may soon lead to advance...s College of Veterinary Medicine have successfully cloned a Duroc pig. The resulting two piglets were recently weaned and are in excellent health. The births ...Easily paralyzed flies provide clues to neurodegeneration
...he Drosophila gene as a probe, other labs have now cloned the corresponding genes in many other insects, inc... As one example, Ganetzky's group discovered and cloned a human gene known as Herg. That gene was the counterpart to one of the fly genes identified among t...Researchers reveal early steps in clone development
...rliest stages of development in normal embryos and cloned embryos. "First, we mapped out some of the early s...e still need to find the optimal culture media for cloned embryos. Once we find out what that is, cloning will probably be more successful," said Latham. "Und...The beginning of the end of flagella
...EB1 occurs in Chlamydomonas cells, the researchers cloned and sequenced the protein to make antibodies specific for EB1. The researchers found that the antibodies bound to the flagella tips, indicating that EB1 stays at the tip, and does not move along the length of the flagella. "This unexpected observatio...'Dog-on-a-chip' could replace drug-sniffing canines
...ep further by incorporating monoclonal antibodies cloned copies of proteins called antibodies that the immune system produces to fight foreign invaders. The researchers used anti-benzoylecgonine (anti-BZE) in the device because it differs only slightly in structure from cocaine, allowing it to bind prefere...Experimental hantavirus vaccine elicits strong antibody response in primates
..., using a harmless device called a "gene gun," the cloned gene is expressed and presented to the immune system. According to senior author Jay W. Hooper, Ph.D., the USAMRIID team constructed an expression plasmid containing the full-length M genome segment of Andes virus, a South American hantavirus. Vacci...McMaster University researchers race to SARS vaccine development
...has come with the work by professor Jim Mahony who cloned the gene that marks an important nuclear protein of the SARS virus. A research team at McMaster then inserted the nuclear protein gene into an engineered common cold virus, or adenovirus vector, and will shortly test this in animals for the protectiv...