Tag: "cloned" at biology news

Gene expressed in 80% of breast cancer patients

...ew gene, BP1, an isoform previously discovered and cloned by Dr. Berg, is expressed in 80% of breast cancer patients in preliminary findings. Dr. Berg, Associate Professor of Biochemistry and Molecular Biology, and team members report that, "Because of these high numbers and our molecular studies, we belie...

The magic behind merlin

...rs of the central nervous system. Although NF2 was cloned a decade ago, this paper by Dr. McClatchey and colleagues provides unprecedented insight into the biological consequences of merlin loss and therefore its role in tumorigenesis. Dr. McClatchey and colleagues have determined that merlin resides in adh...

Cloned pigs differ from originals in looks and behavior

...ty's College of Veterinary Medicine indicates that cloned pigs can have the same degree of variability in ph... there. This dispels the commonly held notion that cloned animals retain the physical and behavioral attributes of the animal from which they were cloned. The...

Seeking comfort from the cold

...type bioluminescent plants. Dr. Zhu and colleagues cloned the gene that had been mutated in this plant, and named it ICE1 (inducer of CBF expression). Further research by the group revealed that ICE1 is also a transcription factor: During periods of cold stress, ICE1 binds to and turns on the CBF3 gene, whi...

Univ. of Pittsburgh Medical Center leads group buying PPL'S cloning, stem cell business

...lantation by making use of organs and tissues from cloned pigs; stem cell technologies focused on production... PPL's creation in March 2000 of the world's first cloned pigs. Chief among the Pittsburgh researchers was Chihiro Koike, M.D., Ph.D., assistant professor of ...

Tracking every egg? AAAS report lists practical options for regulating human cloning

...ieved through other kinds of research that involve cloned cells. The recent AAAS workshop was an important f...es; All donors must provide informed consent; The cloned embryo must not be allowed to develop beyond 14 days; Regulations should protect privacy and confid...

Scientists identify protein channel that mediates body's ability to feel frigid temperatures

...omplete mystery. That changed in 1997 when a group cloned the first sensory molecule, a type of transient re...ian and his TSRI and GNF colleagues identified and cloned a protein called TRPM8, which is the first-known signaling molecule that helps the body sense cool t...

Human sperm may 'smell' their way to the egg, Science study suggests

...rant receptor in testicular tissue of humans. They cloned the receptor, expressed the receptor protein in a line of human embryonic kidney cells--an artificial expression system--and screened for potential ligands. Activation properties of these identified ligands were then tested in human spermatozoa. To t...

Inactive genes may contribute to failure of animals cloned from adult cells, study finds

...BRIDGE, MA Only 1 percent to 3 percent of animals cloned from adult cells survive to birth; many die myster...skirt a major roadblock in cloning. "Most animals cloned from somatic cells fail in all seven species, while animals cloned from embryonic stem cells survive...

Mount Holyoke College series examines advances in human reproductive technologies

...loning of mammalian embryos and produced the first cloned transgenic cow in 1998. He is the author of more t... their own. They want to cure diseases, not create cloned humans." In conjunction with the Weissman Center series, the Mount Holyoke College Art Museum will p...

Popular Science outlines need for long-term studies and more regulation in A.R.T.

...approach. The recent claim that a fringe group had cloned a human caused yet another wave of protests from scientists and politicians over reproductive cloning. It'll cause birth defects, they said, it'll create children with unimaginable problems. But with the spotlight on cloning, Americans missed one imp...

Prion disease may be caused by buildup of cellular trash, say Stanford researchers

...ease without prions," said Barsh. When He and Gunn cloned the gene responsible for the mayhem, they found that the mutants were unable to express a ubiquitin ligase they named Mahogunin. Mahogunin was also identified late last year by scientists at Columbia University School of Medicine. Further experiments...

Data presented on first cloned, double knock-out miniature swine

... in the journal Science that they had successfully cloned the world's first single knock-out miniature swine. The genetic material from these swine was then re-engineered with the aim of knocking out the second copy of this critical gene. These cells were then subjected to another round of nuclear transfe...

Leading cloning experts challenge Clonaid to prove claim

...e been shown to seriously compromise the health of cloned offspring. Randall Prather, distinguished professo...l of Medicine; said that it was highly likely that cloned children would suffer similar problems with their health and this alone should deter scientists from...

Purdue researchers discover basis for biological clock

...h produced the protein within cells. The team then cloned the protein and altered it in ways that produced different period lengths. "We found that we could produce clocks with cycles of between 22 and 42 minutes," James Morré said. "The 'day' which the cell experienced was precisely 60 times the pe...

Cloned pigs behave like...pigs

...ust like pigs. Or at least, that's what a study of cloned pigs found at Texas A&M University. The behavior of cloned pigs, produced last year at Texas A&M, were compared to pigs bred normally. The recent study was co...

Expressing strong concern at human cloning reports, AAAS cautions against overreaction

...ed great concern about recent reports of the first cloned human baby, urging policymakers and the public to treat such claims skeptically until confirmed scientific evidence is in hand. "Such unverified claims, based on work in unregulated, clandestine laboratories, are totally inconsistent with the norms o...

Stem cells put to the test in UNC studies

... - that genetically altered adult liver stem cells cloned from a male rat can turn into functional adult bon...t stem cells derived from one tissue line could be cloned and transplanted to a host where they would be supported by local environmental signals that allowed...

New study pursues the impact of pregnancy on drug efficacy

...everything from street drugs to folic acid. He has cloned a transport system expressed in high levels in the placenta called an organic cation transporter, or OCT3, because it can handle a broad spectrum of therapeutic drugs that contain a positive charge. "We are still trying to figure out the physiologic...

Revealed: How a master protein remodels chromosomes to orchestrate gene expression

... Kohwi-Shigematsu. In a large protein array, using cloned BURs as probes, they isolated the protein they named "special AT-rich binding protein 1," SATB1. SATB1 does not bind to exposed DNA bases; instead, it binds along the minor groove of double-stranded DNA, where there are well mixed As, Ts, and Cs (cy...

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