Scientists isolate premature ovarian failure gene
...mosis and premature ovarian failure. The gene was cloned by Italian scientists led by Giuseppe Pilia of the University of Cagliari, with the assistance of French researchers and NIA investigators. The finding, published in the February 2001 issue of Nature Genetics, establishes blepharophimosis as a pote...Hessian fly genomics research will benefit wheat farmers, others
... This will be the first time an avirulence gene is cloned from an insect," Stuart says. "That would give us ...ercome the resistance, Stuart says. No one has yet cloned either a Hessian fly resistance gene in wheat or the corresponding genes in insects, but Stuart is h...First genetically modified monkey, reported in Science, may promise medical advances for humans
...o last year reported the first monkey successfully cloned by embryo splitting (see Science, 14 January 200...rding to Schatten. "Monkeys like ANDi and Tetra, a cloned monkey, will quickly but safely help us determine if innovative therapies are safe and effective," h...Scientists bypass major hurdle to hemophilia gene therapy
...s called AAV to infect cells and thereby deliver a cloned gene into an animal's body. Previous studies used only type 2 of six known AAV serotypes, each of which differ in their protein wrapper. This time, however, the Carolina researchers tried five of the six, comparing factor IX production of AAV types 1...Cloning can turn back the developmental clock
...show that X-inactivation is random in the cells of cloned animals. The egg therefore is able to reprogram th...n and followed its course in different lineages of cloned embryos. This allowed them to tell, based on whether the cells were dark or fluorescent green, which...Hopkins scientists show enzyme is key to hallmark of Alzheimer's
...ttered with them. Last year, five research groups cloned the gene for the enzyme, called beta-secretase, but the Hopkins scientists say they are the first to show the enzyme is responsible for forming the molecules that comprise plaque within the brain's nerve cells. Beta amyloid - the plaque molecule - f...Researchers identify molecule that senses osmotic pressure in vertebrates
...nals to the central nervous system. The scientists cloned VR-OAC from rat, mouse, chicken and human gene lib... in the Laboratory of Sensory Neuroscience who had cloned VR-OAC from a chicken inner ear gene library. Liedtke thought that VR-OAC could be an ion channel th...Science: Prion proteins may signal trouble -- literally
...the prion's signaling ability, the scientists used cloned mouse-stem cells (1C11) that can convert into fully functional neurons. These neuronal cells are known to continuously produce normal prions, and they can differentiate into two types of neuronal cells, which produce and respond to either serotonin o...Biotechnology research to grow from embryonic start
... which was used to produce Dolly, the worlds first cloned sheep. This could be done by fusing an adult cell with either an egg cell, or with an ES cell, that has had its genetic material removed, and then using the resulting stem cells to derive specialised cell types for therapeutic applications. Although...Cloned pig debuts in Science, sets the stage for organ transplants
...mal Industry in Japan. The female piglet was cloned by microinjecting genetic material from fetal pig ...rue colors were apparent from the beginning. Xena, cloned from cells from a strain of black pigs, has a black coat that contrasts sharply with the white coat ......ly, reduce root growth. Studying the response of cloned ozone-sensitive and ozone-tolerant white clover plants, McGrath found that ground-ozone levels were greater than 80 parts per billion (ppb) for 121 hours in 1998, and 184 hours in 1999. The highest ozone levels were reached on June 26, 1998, when c...TSRI scientists clone gene that regulates circadian rhythms in plants
...ists at The Scripps Research Institute (TSRI) have cloned a gene that regulates circadian rhythms in plants, providing an increased understanding -- on a molecular level -- of the processes that enable organisms to anticipate and adapt to daily variations in the environment. According to Steve Kay, Ph.D., P...Molecular structure key to allergies and asthma is identified
...nto the lock." The gene for the IgE receptor was cloned 14 years ago by Jardetzkys collaborator, Jean-Pierre Kinet, professor of pathology at Harvard Medical School and director of the Laboratory of Allergy and Immunology at Beth Israel Deaconess Medical Center. "I have been waiting for this moment for ...New robotic microarray technology finds novel genes involved in cardiac hypertrophy and recovery
...s from the Genome Sciences Department's library of cloned genes on glass microscope slides. Each gene fragment is capable of binding to the messenger RNA (mRNA) that codes for a particular gene's protein product. Messenger RNA extracted from heart tissue was placed on each slide. The mRNA from hypertrophied......, healthy genes. "Over the past 15 years, we have cloned and identified a number of genes from the brain which we thought were important for a particular disease," says Khalili. "Now, with this information, we can go back and put our information in the context of the information from the human genome proj......hannels, this reductionist approach leads from the cloned molecules to the elucidation of how they shape the...ong way to go, but the work of correlation between cloned channels, native currents and their function is allowing the first steps to be taken....Northwestern researchers clone gene responsible for inner ear motor
...ce and molecular biology experts, researchers have cloned a gene, named after the musical notation presto, t...the University's Medical School, have successfully cloned the gene Prestin which codes for a protein (prestin) that is an important molecular motor in the out...Cloning reverses aging in cow cells, Scienceauthors say
...igns of the premature aging reported for Dolly the cloned sheep, researchers say in the 28 April issue of S...ding erases a lingering doubt about the utility of cloned cells by demonstrating that the process doesn't automatically rob cells of a normal lifespan. In fac...Advanced cell technology reports reversal
...e results of previous research indicated that even cloned cells retained the aging clock of the clone donor.... alternative cloning technique to create Dolly the cloned sheep that has been so prominently featured in the media, reported that she was actually aging faste...Cloning reverses aging in cow cells, a milestone in medical research
...ts of previous research that resulted in Dolly the cloned sheep (created by a different cloning method) repo...ear transfer experiments. ACT produced six healthy cloned calves from these donor senescent cells. "The significance of this finding is that you can, in essen...