Argonne leads new Midwest Center for Structural Genomics
... Molecular Biology facility can produce 400 to 800 clones a week. Manual methods produce only 20 to 40. Plans to quadruple production are in the works. Computer researchers also sift through data to point researchers toward what could be the most important proteins to study. The center will first organize ...Cloning can turn back the developmental clock
...e first time that the process of X-inactivation in clones occurs in a manner similar to that in normal development. Since Dolly was first cloned, researchers have debated whether she has random X-inactivation as normal females do or the same X chromosome inactivated in all her cells (the X that was inactiv...Scientists report first complete genome sequence of a plant
... in its entirety and provide an ordered set of DNA clones for sequencing (BAC, bacterial artificial chromosome). This analysis of the Arabidopsis genome was completed by Wilson, Marco Marra, and their colleagues at the Washington University Medical School Genome Sequencing Center with assistance from McComb...Wistar scientists add difficult-to-sequence stretches to human genome data
...stantial portions of telomeric DNA, but Riethman's clones include most of these regions. While the primary a... extend into these regions or because the telomere clones contained repeated DNA segments that make it difficult to determine where the clones overlap with th...Amidst genome data, a practical tool for researchers
...e a physical map of the human genome. "Because our clones are highly accurate islands of DNA sequences throughout the genome, they provided anchors for researchers doing the sequencing to check their results when assembling the genome sequence," said Dr. Cheung, who co-authored another paper in the special ...Zebrafish could become genetics 'lab rat' of choice
...ction by disabling a single gene, and then raising clones of that test subject to see how they develop without the missing gene. Such experiments are called knockout experiments, because the gene is turned off, or knocked out. Over the past decade, plant scientists have used a small mustard plant, called Ar...LSU veterinarians deliver cloned calves by caesarian section
...ed LSU veterinarians that only 25 percent of their clones were born as completely healthy calves and that most need intensive care at birth due to unexplained respiratory problems. Although the respiratory complications are still a puzzle, Cyagra believes they are most likely a cause of the artificial proce...New hope for neurodegenerative disease sufferers
... human 14-3-3 genes in the flies. The flies are clones of each other and are raised in the same environment, so the only difference between a normal fly and a fly with a human 14-3-3 gene is that single gene, Skoulakis explains. The gene can be turned on and off with heat shocks. It is activated betwe...Scientists track down the root of cloning problems
...ontinue to plague the field of animal cloning: few clones survive to term and those that do are grotesquely ...kground of the donor cell, the gross overgrowth of clones results from the actual procedure of cloning. The findings will add to the crucial body of k...LSU researchers find cause of respiratory diseases in cattle
...ttle. This new method involved the use of specific clones of cultured animal cells. Once the samples from the cattle were applied to the cloned cell cultures, Storz observed the coronavirus. The respiratory coronavirus infects cells that line the upper and lower respiratory tracts, including the lungs. ...Toxic compound opens potentially important cell gates
... to a variety of other functions. Scharenberg sent clones of the Nudix genes he'd found to Bessman, and Dunn transferred the shorter gene into E. coli bacteria. When the bacteria used the gene to make proteins, Dunn tested them against a series of compounds that bind to Nudix boxes. The protein would only ...University of Georgia unveils technique to improve success rate of cattle cloning
...nimal and dairy science department. The calves are clones of a cow that had grown too old to reproduce but had desirable traits worth preserving, he said. The cloning process doesn't change the genetic makeup. It repeats it, just like an identical twin in nature. "Improvement in the efficiency of cloning wi...University of Georgia unveils technique to improve success rate of cattle cloning
...nimal and dairy science department. The calves are clones of a cow that had grown too old to reproduce but had desirable traits worth preserving, he said. The cloning process doesn't change the genetic makeup. It repeats it, just like an identical twin in nature. "Improvement in the efficiency of cloning wi...Science researchers report 'extremely unstable' gene expression in cloned mice
...nucleus into an emptied egg, die before birth. The clones that do survive frequently have respiratory and ci...documenting the changes in gene expression for the clones themselves, the investigators turned their attention to a second question: were these abnormalities ...New study shows normal-looking clones may be abnormal
...vidence to show that even seemingly normal-looking clones may harbor serious abnormalities affecting gene ex...ross overgrowth in cloned animals. They made mouse clones from embryonic stem (ES) cells and monitored the activity of imprinted genesdevelopmental genes that...Survival of quaking aspen groves a complex problem
...mgjohnson@fs.fed.us by email. "Because aspen are clones and regenerate vegetatively, some of the groves are 8,000 years old," says Taylor. "Aspen have rarely been observed to regenerate from seed, however they did after the recent Yellowstone National Park fires." The Penn State researchers suggest that ......sel Matthew Marca disagrees. He insists that since clones will share the fingerprint of the original person,...ight. When New Scientist pointed out to Marca that clones are not exact copies but often contain a new genetic component-mitochondrial DNA from the egg used t...UC Davis' first cloned calf born, succumbs three days later
... companies. The current technology used to produce clones in the laboratory is called nuclear transfer because it is based on moving the nucleus of one cell into another cell.The nucleus -- the center part of the cell that contains its DNA -- is withdrawn from an egg cell of one animal. Then a cell is taken...NSF awards University of Georgia $8.7 million for crop genetics research
...ical curiosity where plants produce seeds that are clones of the mother plant. Apomixis is not a common trait but it is more frequently observed in the grass and sunflower families, Ozias-Akins said. This trait is rare in domesticated plants and absent from our major crops. If the trait for apomixis could b......s are based on the health problems seen in the few clones that do survive, which have also prompted the FDA to ask companies not to sell food from clones until it has been proved to be safe....