Molecular "Fossils" Of Early Life
...ll break themselves free from the grid. By cloning the DNA sequences that are washed away by the amino acid andthen repeating the process several times, the Yale biochemists isolate desiredenzymes. "Our latest findings not only improve our understanding about theorigins of life, they also expand our...First Reproducible Cloning Of Mammals From Adult Cells Reported In Nature
... HONOLULU, July 22, 1998 -- The first reproducible cloning of a mammalfrom adult cells, which has successfull...h.D.,of the University of Hawaii. The distinctive cloning technology, described as the Honolulu technique,could be more viable for the production of drugs usi...Blindness Linked To The Cytoskeleton?
...ular-biology strategy known as ‘positional cloning approach’. The isolation of genes by positional cloning is based on the location of the gene in the human genome, without detailed information on the ...Subtle Changes In Brain Receptor Gene May Have Significant Consequences For Addiction
...NorthAmerican and 1 multiethnic. Using molecular cloning techniques and polymerase chain reaction, the scientistsidentified five SNPs of the mu opioid receptor gene in the coding region. Two ofthe SNPs were identified previously by researchers at other institutions, butthe other three are described for the...... years ago in anticipating the importance of gene cloning technology for the future of biotechnology. "In 1980 he decided to establish a molecular genetics research group at LORRE, and he had the courage then to put the responsibility for establishing this group, as well as for carrying out this importa......losely. That we feel so differently about cloning when humans might be involvedgoes to the heart of many arguments about these "genetic gods." "If genes were merely passive backdrops to human existence, why shouldwe care about the prospects of human cloning?" asked Avise. "But most of us doc...New "Gene Map" Doubles Number Of Genes
.... "It will immediately speed up positional disease cloning as well as let the worlds of pure and applied biology move on solidly to functional genomics." "It has been estimated that the human genome contains between 60,000 and 80,000 genes, so the new Gene Map brings us nearly to the halfway point," observe...Researchers Announce Breakthrough In Transgenic Animal Technology
.... The efficiency of the new technology could make cloning and pronuclearmicroinjection economically obsolete for many biopharmaceutical purposes. Italso paves the way to applications of biotechnology in agricultural livestock,similar to those that have changed crop agriculture in recent years. Thetechnology...Gene Discovery Paves Way For Preventing Deadly Bacterial Shock
...ators of the body's defense againstinfections. Its cloning culminated a five-year effort in which the scientistsmapped a minute region of the mouse genome, identified every gene in the region,and then pinpointed Tlr4. The project was intensely competitive with severalgroups of scientists from industry and ac...Atlantic Salmon Cancer Virus Identified
.... Researchers used PCR (polymerase chain reaction) cloning and gene-sequencingtechniques developed at Cornell to make the first positive identification of thevirus, believed responsible for tumors that killed breeding-stock Atlanticsalmon in the U.S. Fish and Wildlife Service hatchery in North Attleboro, Mas...Human Neural Stem Cells Advance Distant Prospect Of Reseeding Damaged Brain
...the adult human brain. And two teams described the cloning of humanembryonic stem cells that can generate cel...g theintertwined debates about the ethics of human cloning and fetal tissue research. Earlier work in the field from a small group of laboratories incl......s made possible by a method, refined by Tailor,for cloning the receptors relatively quickly. "The basic technique we are usingis to isolate a gene from a cell which is susceptible to the virus and express that gene in cells that are resistant to the virus. If the resistant cell becomes susceptible, we know w...UF Scientist Seeks Super Sea Oats
...lants from around Florida." The final step will be cloning the superior plants in a laboratory usingmicroprop...is whatwe're after," Kane said. "We've developed a cloning technique for sea oatsthat allows us to take one sea oat with superior characteristics andreplicate ...Allelix Clones Receptor For Intestinal Growth Factor GLP-2
...opharmaceuticalsInc. (TSE/ME: AXB) will report the cloning of the receptor for Glucagon-likePeptide 2 (GLP-2)...with the most severe form of these diseases. "The cloning of this naturally occurring receptor is a critical step indetermining exactly where and how GLP-2 fu...Reinventing Humans Is Focus Of Virginia Tech Program
...lthough not required). The recent media focus on cloning of animals has alerted the general public tothe rapid pace of work now taking place in human genetic and reproductivetechnologies. New genetic-engineering procedures now permit human genes to beidentified and transferred. Researchers are developing t...Millennium Clones Diet-Induced Obesity Gene
...that region'srole in body weight regulation. "The cloning of the mahogany gene and the identification of its protein productare major first steps in achieving a better understanding of their roles incontrolling weight based on the amount of fat in a diet," said Karen Moore,Ph.D., director of genetic systems...Researcher Awarded Patent For System To Fight Multiple Diseases
...e late 1970s andearly 1980s when he was using gene cloning to express protein antigens fromstreptococcal bact...en into another was not possible because such gene cloning wasprohibited by the National Institutes of Health (NIH) Guidelines for RecombinantDNA Research. Cu...Studies Of A Gene For A Rare Form Of Rickets Shed Light On Vitamin D Deficiencies
...crinologist Walter L. Miller, M.D.,collaborated in cloning the gene for the enzyme in 1997. The 1-alpha hydro...bility to makevitamin D in its active form. Since cloning the 1-alpha hydroxylase gene, Portale and his colleagues haveidentified mutations in 19 patients. Ch......sic Sciences divisions, on a newsystem for genetic cloning that uses phenotypic localization to "interrogate thehuman genome." The BIO '99 meeting is expected to draw an estimated 5,000 biotechnologyindustry leaders from 40 nations, including representatives from many ofWashington's 120 biotechnology and med......agimachi, who introduced the HonoluluTechnique for cloning mice a year ago, have used the technique to produce thefirst male mice clones. Their report appears in the June issue of the journalNature Genetics. Like Dolly the sheep, Cumulina and the scores of subsequent mice clones producedat the University of ...