Nematode makes scientific history
...y of the genome sequence will facilitate molecular cloning of plantparasitic nematode genes by using primers that match nematode sequences ofinterest. These are exciting times for plant molecular nematologists because, ifgene order is highly conserved, simply sequencing regions adjacent to conservedgenes wil...First complete physical map of a higher plant genome
...cial chromosome) clones, the premier system for cloning and maintenance of large genomic DNA. ...ACs (yeast artificial chromosomes, a system for cloning and maintenance of large DNA fragments). The map presented here is highly reliable and offers ...... region of mousechromosome 6, laying the basis for cloning the mouse Pas1 gene and providingessential clues f...ancestral source, a discovery that will facilitate cloning the Pas1 lungcancer gene in mice. Contact Information: Tommaso A. Dragani Department of Experimenta...Protecting the rice bowl: Chromosomal mapping of the rice blast fungus
...M. grisea genome. Furthermore, by facilitating the cloning of new genes, the map immediatelyboosts efforts to determine how M. grisea infects host rice plants andparticularly how the fungus overcomes host defense mechanisms. This knowledgeis essential not only for combating rice blast but for understandingh...Biotechnology requires training across disciplines, and in business
... PPL Therapeutics, the company that wasinvolved in cloning Dolly and now produces human therapeutic enzymes in the milkof farm animals. Virginia Tech faculty members have also established companiesto produce human proteins in transgenic plants, produce vaccines, killcockroaches, protect crops from fungi, and...Researchers discover genetic basis of heritable sleep disorder
...ify the search for the gene involved. "Mapping and cloning a gene can takefive years or longer," said Ptácek. "We hope to have the FASPS gene muchsooner than that." He added that once the gene is in hand, "we will study the correspondingprotein. Such studies will shed light not only on the function o...UMass virologist publishes book on "The Real Science Behind 'The X-Files'"
...book, they'llunderstand what gene therapy is, what cloning is, and what genetic engineeringis. They'll understand what chromosomes and nucleotides are. They can base theiropinions and votes on real knowledge, rather than on fear." But although the topics are serious, the book is a lively read which includess...Seeing one weapon from a food-borne pathogen
...seudotuberculosis causes illness, Isbergset about cloning genes from Y. pseudotuberculosis and inserting them oneby one into a second bacterium used frequently in laboratory research. Herealized he had made an important discovery when a strain of the laboratorybacterium harboring a single Y. pseudotuberc......very careful analysis of the genomic region." The cloning of Tcr paves the way for the molecular investigation of sperm motility and may turn up human genes involved in some forms of infertility. It is also possible that transmission ratio distortion may exist in other mammals or even in humans which can ...UNC selected as one of two regional mutant mouse resource centers in nation
...vements in mouse cloningprocedures. Genotyping and cloning experiments will be conducted in the Animal Models Core at themedical school. The research moneys also will go toward maintaining and distributing mutant mousestrains....Scientists develop most efficient mouse cloning strategy to date, create transgenic clone
...as produced the most efficient results to date for cloning mice. He is also the first mouse clone whose gene...have a major impact on improving the efficiency of cloning in general. In the February issue of Nature Genetics, researchers, led by Dr. Rudolf Jaenisch at the...New institute formed to distribute human stem cells
...ys. For example, use of the experimental cells for cloning or intermingling with intact embryos will not be permitted. Founded in 1925, the Wisconsin Alumni Research Foundation is the oldest and one of the most successful of all university intellectual property organizations. Through the management of a larg...Researchers link genetic defect to 'head-rush' disorder
...ephrine transporter gene. Blakely participated in cloning the norepinephrine transporter in 1991 and has studied it and related neurotransmitter transporters ever since. Nancy L. Flattem, a medical student in Blakely's group, hunted for a mutation by isolating DNA from the original patient's blood, sequen...New technique improves accuracy of gene tests
... process. The cell fusion step is followed by cloning of selected cells and culturing them until enough cells are available for testing. The entire process takes two to four weeks. It also requires fresh, human cells (no older than 48 hours). W...Scientists clarify much-sought enzyme, pave road to cancer therapy
...gist Carol Greider,Ph.D., who led the team. After cloning the gene for the "business end" of the telomerase molecule in32 different animals -- from shrew to elephant -- the researchers comparedthe structure of the resulting enzyme. They found four common areas highlyinvolved with the enzyme's working, rega...Cockroach birth control from gene discovery
...roductive system of the male cockroach. Success in cloning five P450 genes from the German cockroach was announced by Zhimou Wen today (March 28) at the national meeting of the American Chemical Society (ACS) at the Moscone Convention Center, in San Francisco. Wen is a graduate student working in the labora...Nerve protein shown crucial to sensations of pain from heat, injury
...l researcherin Julius' lab, attracted attention by cloning the gene for the capsaicinreceptor. A number of pharmaceutical companies have since begun screening drugsto inactivate the receptor.) The new study shows that activation of the capsaicin receptor contributes topain in normal, healthy mice, and demons...Cloning reverses aging in cow cells, a milestone in medical research
...e among the investigators involved in an important cloning study that will be released later this week in the...ort, the researchers described how they used a new cloning technique to rewind the aging clock in cells. The clock is considered to be the strand of DNA at the...Advanced cell technology reports reversal
...h may be the path to successful use of therapeutic cloning techniques to cure some of humankind's most intran...port, the researchers describe how they used a new cloning technology to literally rewind the aging clock in cells. Virtually all types of body cells, except r...New fertility technique to help women have own genetic baby from donor egg
...onation. Cell fusion techniques, used mostly for cloning mammalian eggs, involve electrofusion and are not suitable for human eggs because the eggs are almost always activated by the process. In the experiments reported today on human eggs, the researchers have successfully transferred nuclei by two meth...