Tag: "cluster" at biology news
Gene clusters predict atherosclerosis severity, susceptibility
...ms of severity of disease, the researchers found a cluster
of 208 genes that predicted severe disease in 29 out of 31 (93.5 percent) tissues samples, and a cluster
of 28 genes that predicted location of disease in 59 out of 63 samples (93.6 percent). In gen...
Spun from bone
...ts explain how 100 nanometer spheres of amelogenin cluster
like bowling balls around developing enamel crystals, forcing the crystals to elongate into thin, weaved strands that endow enamel with the strength of steel. The discovery is a milestone for those who would wish to nano-engineer tissues, implants a...
New hydrothermal vents discovered as 'South Pacific Odyssey' research begins
...au Basin in the South Pacific has discovered a new cluster
of hydrothermal vents along a volcanically active crack in the seafloor. About a mile and a half down, the basin could hold answers to questions about the origin of life on Earth, say the scientists, whose plans for their "South Pacific Odyssey" inc...
Human chromosome 5 final sequence analysis released to public
... specific gene. Other chromosome 5 genes include a cluster
that codes for interleukins, molecules that are involved in immune signalling and maturation and are also implicated in asthma. The spaces between the genes are as important as the genes themselves, said Eddy Rubin, JGI's director. "In addition to di...
Cell's gatekeeper for ammonia revealed in unprecedented detail
...structure. The research reveals that AmtB channels cluster
in groups of three. Three slightly different proteins are known to associate in the blood group antigenic Rh factors, Stroud said, and the new research now reveals how they are physically associated. While some ammonia can pass through cell membranes...
Hunting illusive signs of natural selection
...es easier to identify," says Shriver. "We found a cluster
of four genes that appear to be heavily selected."...earchers cannot identify an individual gene in the cluster
of four that was selected, but one of the genes, TRPV6 might be involved in susceptibility to aggres...
Bone marrow cells routinely help with wound healing
...le seems to be over, the bone marrow-derived cells cluster
within the healing area of a wound. The researchers ran these skin cells through a flow cytometer to separate them into green and non-green fractions and found only the green cells in the skin produced collagen type III, which is one of the two most...
Images reveal how rotavirus - leading cause of diarrhea - enters cells
...er layer project 60 "spikes," each consisting of a cluster
of VP4 molecules. Dormitzer and colleagues trimme...zymes cause two of the three VP4 molecules in each cluster
to form a rigid spike, priming the virus to attack the cell and positioning the spike "head" to bind...
JGI announces community sequencing program portfolio
...genomics has suffered since only a closely related cluster
of cereals and the mustard Arabidopsis have been sequenced. This will be a triumph for international plant science." Mosses were among the first plants to colonize the land, 450 million years ago. They predate the flowering plants by some 200 mill...
New clues to hereditary blinding disease found
...or many diseases." Hwa and colleagues discovered a cluster
of RP mutations localized within and around the area where zinc is supposed to bind with rhodopsin. They investigated different amounts of zinc at the rhodopson binding site to determine what amount leads to a successful binding and what causes the ...
Excess thyroid hormone harmful to fetus
...est studied is an extended family in the Azores, a cluster
of small islands about 900 miles west of Portugal. In this family, the mutation has been traced back four generations to a single founder couple in the late 19th century. In this paper, Refetoff, working with Azorean endocrinologist Joo Anselmo, loo...
Clusters of alterations on PIK3CA gene found in brain cancers
...rt tumor growth. Yan and colleagues pinpointed a cluster
of 13 mutations on two particular areas of the PIK3CA gene, exons 9 and 20. The mutations were identified in 14 percent of anaplastic oligodendrogliomas, 5 percent of medulloblastomas, 5 percent of glioblastomas and 3 percent of anaplastic astrocytom...
New glycan arrays discover autoimmunogenic activities of SARS-CoV: concern over monkey vaccine
...eties are expressed by a viral glycoprotein, their cluster
configuration could differ significantly from thos... Institute, this antibody is specific for a unique cluster
of sugar chains displayed by the gp120 glycoprotein of HIV-1 and is able to neutralize a broad-range...
Casanova or caveman: Scientists isolate nerve cells that choreograph male fly's courtship behavior
... courtship behavior is actually choreographed by a cluster
of nerve cells embedded in the central nervous system of the male fly. When these cells fail to function properly, the courtship ritual breaks down and the male is transformed from a suave Casanova into a clumsy brute that tries to force himself on u...
Carnegie Mellon neuroscientist develops tool to image brain function at the cellular level
...ncing the world through one whisker. By locating a cluster
of glowing neurons, she was able to precisely identify the area of the brain involved in processing sensory input from the single whisker. Once the neurons of interest had been located, Barth then examined each neuron to determine how its electrophys...
Cell death protein has surprising role in cell migration
...in point in development of the egg, a single small cluster
of these epithelial cells normally detaches from t... cells were missing Rac's function, the epithelial cluster
rarely made it even halfway to the oocyte. Returning a working Rac protein to these cells allowed ab...
Comparing primate genomes offers insight into human evolution
...aracteristics that are unique to each species. One cluster
of genes that amplified only in humans was mapped to a genomic area that appears prone to instability in human, chimp, bonobo, and gorilla. This region has undergone modifications in each of the other descendent primate species, suggesting an evoluti...
Researchers discover how worms' noses sense oxygen
...and clumping is a peculiar behavior in which worms cluster
around the border of the Petri dish instead of spreading evenly around the surface. Marletta and his colleagues, members of the California Institute for Quantitative Biomedical Research (QB3), determined that the bacteria the worms feed on are at a h...
Molecular image of genotoxin reveals how bacteria damage human DNA
...e three-unit toxin contains a long, deep groove, a cluster
of ring-shaped molecules, called the "aromatic patch," and a dangling protein tail that can block a key portion of the CdtB subunit that is necessary for DNA cleavage. "We're not sure what the role of the cleavage-blocking protein tail is, but the st...
First genetic comparison of purebred domestic dogs produces surprises
...enetic comparisons also enabled the researchers to cluster
many breeds according to shared lineages. The rese... The researchers said they were surprised that the cluster
containing the more ancient breeds of Asian and African origin included such a diversity of breeds -...
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