Tag: "cocaine" at biology news

Genes may be central to cocaine addiction

...components of the biological machinery that causes cocaine addiction, researchers have found. Peter Kalivas a...s produced by the Homer genes might play a role in cocaine addiction. Members of the family were known to be activated by cocaine, and reduction of activity in...

'Crack babies' do better when placed with non-family caregivers

Ever since the epidemic of cocaine and crack use that began in the 1980s, researchers...the development of children born to women who used cocaine during their pregnancy. Initially, research focused on the potential negative impacts of the drug it...

Drug addiction, learning share common brain protein

...ork by other researchers revealed that exposure to cocaine triggers changes in a brain region called the stri...e striatum of mice that had "super-sensitivity" to cocaine due to a genetic defect or prior cocaine exposure, with the gene activity in the same brain region o...

'Dog-on-a-chip' could replace drug-sniffing canines

...d by an electronic "dog-on-a-chip" that sniffs out cocaine and other narcotics. Scientists at Georgia Tech ha... chemical from a group of many similar ones (e.g., cocaine from coffee grounds). The dog-on-a-chip can sense cocaine at a few trillionths of a gram. This sensi...

Researchers discover genes that distinguish human, nonhuman primate brains

... vaccines for AIDS and malaria, and treatments for cocaine addiction and Parkinson's disease. Other research programs include cognitive development and decline, childhood visual defects, organ transplantation, the behavioral effects of hormone replacement therapy and social behaviors of primates. Leading res...

Neurons involved in drug addiction relapse identified

...ould press a lever and self-administer cocaine. No cocaine was given if the animal pressed the lever in the a...h. When the lever was returned to the cage, but no cocaine was provided and no tone was sounded, the animals ignored the lever. But when the tone was again sou...

OHSU researcher publishes first measurements of 'free-base' nicotine in cigarette smoke

... researchers believe that chemicals like nicotine, cocaine and methamphetamine become increasingly addictive the more rapidly they are delivered to the brain. Addiction expert Jack Henningfield, Ph.D., a professor at the Johns Hopkins University School of Medicine and former adviser to past FDA Commissioner ...

DNA profiling used on cannabis plants

...ale of highly processed or synthetic drugs such as cocaine and ecstasy. Nor does the team think it would work with hashish, which is made from resin exuded by cannabis plants, as not enough cellular material can be recovered. If the cannabis profiling technique does prove to be an effective tool in investiga...

Rutgers receives $22.6 million to investigate genetics of mental disorders

...arch on mental diseases; disorders such as heroin, cocaine and tobacco abuse; diabetes and obesity; and aging and longevity. "The center will play a critical role in future genetic studies on mental disorders in the post-genomic era," said Steven Moldin, NIMH project director for the center. "Rutgers has as...

Executive functioning in children prenatally exposed to alcohol

...ts of prenatal exposure to alcohol, marijuana, and cocaine on EF, published in this month's Alcoholism: Clinical & Experimental Research , has found that prenatal alcohol exposure of less than one drink per day can impair EF in early childhood. "The results of this study confirm a possible brain-based path...

Genetically modified mice provide information on treatments for cocaine dependence

...remature death. Among those drugs that are abused, cocaine is considered one of the most powerful. Yet no effective medications exist to treat cocaine abuse, dependence or withdrawal. In order to develop these needed medications, a better understandin...

Research shows cocaine 'reward' picture more complicated than scientists thought

...isrupted in specially modified laboratory animals, cocaine still provides reinforcing "rewards" to animals th...hen effective therapies will be available to treat cocaine addiction, the scientists say. Dr. Linda Dyksta, William Rand Kenan Jr. professor of psychology and ...

UNC scientists find important new clue to puzzle of addictive behavior

...e is a major new clue to what causes addictions to cocaine and possibly other drugs including alcohol and tob...moments before laboratory rats decided to get more cocaine by pressing on a special bar. That chemical signal, triggered by an outside cue, appears to cause th...

Laser-pulse technique could aid drug design

...ocainelike analog compound to block the effects of cocaine poisoning on the nervous system, he says. Hess dis...other neurons," Hess says. The recent discovery of cocaine analogs, one application of the laser-pulse photolysis technique, will be reported in the scientific...

New study validates criteria for safe, rapid treatment of patients with cocaine-related chest pain

...sicians and patients alike." During the hour after cocaine is used, the risk of heart attack increases 24-fol...ays after discharge. All four had continued to use cocaine after their release and had at least two other cardiac risk factors. In 2000, there were 175,000 coc...

Early marijuana use increases risk of drug and alcohol problems later in life

...research is based on the fact that most heroin and cocaine users report first having used cannabis," says lea...s also used other drugs at higher rates, including cocaine and other stimulants (48 percent) heroin and other opioids (14 percent) and hallucinogens (35 percen...

Cocaine harms brain's 'pleasure center,' addict study finds

...OR, MI New research results strongly suggest that cocaine bites the hand that feeds it, in essence, by harmi... the very brain cells that trigger the "high" that cocaine users feel. This first-ever direct finding of cocaine-induced damage to key cells in the human brain...

A new approach holds promise for reducing cocaine craving

...f the changes in brain chemistry caused by chronic cocaine use has suggested a novel treatment that could reduce the intense craving that forms the core of cocaine addiction. "Our studies show that administration of an existing drug n-acetyl cysteine, which is us...

Dr. Francis White, FUHS/CMS, receives MERIT Award

...avioral consequences of repeated administration of cocaine and withdrawal from cocaine dependence in animal models, (2) correlating those behavioral alterations with specific neuroadaptat...

Conference focuses on drug abuse effects on neuroimmunity, infectious diseases

... chronic use of drugs such as nicotine, marijuana, cocaine and opiates can promote the development of infectious diseases by altering immune and neuorendocrine functions. The symposiums scheduled for Friday Oct. 4 are "The Neurological Basis of Drug Dependence and Its Effects on the Immune System" and "Mech...

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