Protein Implicated In Multiple Sclerosis
...eir own. In the current study, Trotter and colleagues isolated T cells from 12 MSpatients. They cultured the cells and exposed them to short strings of aminoacids or peptides. These peptides were identical to various parts of the PLPmolecule. If the T cells recognized a particular peptide, they prolifer...Researchers Unable To Document Existence Of Transient HIV Infection In Infants
... for the current research: A few years ago,she and colleagues were studying the resistance of HIV to the AIDS drug, AZT. Intheir research, they encountered the case of a mother who had had two positivecultures for HIV, and her baby, who had tested positive three times. Duringlater testing, HIV could not be foun...Researchers Identify A Gene That Causes Juvenile Polyposis
...nt." It took less than two years for Howe and his colleagues to pinpoint the errantgene. Howe credits the Human Genome Project for acceleration the process of geneidentification, particularly for making available good markers to help determinethe chromosome where genes are located. The group was able to identi...... presented earlier this year, NaotoUeno, M.D., and colleagues at The University of Texas M.D. Anderson CancerCen...ector Immunotherapy and Vaccine Program, alongwith colleagues at Targeted Genetics and Wayne State University, conducted theresearch presented at ASCO. The Phase...ASU Scientists Join NASA Astrobiology Institute
...evolution oflife, geochemist John Holloway and his colleagues will be study the organicchemistry of hot vents of deep sea "black smokers" through a combination oftheoretical, lab-simulated and field-based methods. Holloway's goal is todetermine if life could have had an origin at high temperatures, a suggestion...COGA Suggests Genetic Loci For P3 Brain Wave Abnormality
...of New York Health Science Center at Brooklyn, and colleagues in the six-university Collaborative Study on the Genetics of Alcoholism (COGA)* identify in the May Electroencephalography and Clinical Neurophysiology (Volume 108, Number 3) chromosomal regions that may underlie the functional organization of huma...Neurogenetics Lab Scan Suggests Genetic Linkage On Chromosomes 4 And 11
...predominantly Caucasian families, Dr. Long and his colleagues identified a second region on chromosome 4 near the alcohol dehydrogenase (ADH) gene cluster as suggestive of linkage to alcoholism resistance. One of two principal enzymes involved in alcohol metabolism, ADH catalyzes the conversion of alcohol to ac...COGA Genome Scan Suggests Linkage On Chromosomes 1,2,4, And 7
...gton University School of Medicine, St. Louis, and colleagues at that university and others* in the NIAAA-supported Collaborative Study on the Genetics of Alcoholism (COGA) report in this month's Neuropsychiatric Genetics (Volume 81, Number 3) highly suggestive evidence on chromosomes 1 and 7 and more modes...Scientists Say Latently Infected Cells May Stoke the Fire of HIV Replication
...nd Infectious Diseases (NIAID), and colleagues argue that so-called latently infected ... reported late last year, Dr. Fauci and colleagues in NIAID’s Laboratory of Immunoregulation detected unintegrated H...Researchers Identify Function Of Brain Receptor Subunit Linked To Memory, Stroke, Dementia
...uroscience atBrigham and Women's Hospital, and his colleagues cloned a gene that he andNobuki Nakanishi, HMS ass...ve cells. In anatomical studies, Nakanishi and his colleagues founda striking increase in the number of dendritic spines--sites where synapses areformed--on the n......erite Blake Wilbur Professor of Chemistry, and his colleagues published the technique that allowed them to read out the contents of individual vesicles in the journal Science earlier this year. Cells use vesicles to signal each other in a variety of ways. Such messages include mail to the brain that says "ouc......onths that was intended. Fliermans and his colleagues discovered the problem when they examinedsamples of cladding materials that had been dunked in seven of the eight basinsat Savannah River for up to a year. The samples were tiny rods, each 1centimetre long, imbedded in Teflon and lowered to four diff...Nice Motor...Shame About The Smell
...lergic reactions. Robert Simmons and his colleagues at Georgia State University in Atlantahave recorded at least 15 different types of fungi growing in the foam and gluethat surround the heat exchangers in car air-conditioning systems. Bacteria alsoform a biofilm on the surface of heat exchanger coils......slyill. That's the message from Clement Ng and his colleagues at the MilwaukeeHealth Department, who have found ...y pet dogs in the Milwaukee area. When Ng and his colleagues examined 300 stool samples from show dog clubs,boarding kennels and veterinary clinics, they found C...UB Fertility Researchers Find They Can Predict Pregnancy By Assessing Two Sperm Abnormalities
...nt pregnancies in the couples studied, Burkman and colleagues determined that samples showing more than 14 percent premature chromosomal decondensation or more than 7 percent premature acrosome reactions had only a slim chance of leading to a pregnancy. "We were surprised to see that these two factors re...Gene Therapy May Suppress Uterine Fibroids
...& Gynecology details the results Christman and his colleagues produced in laboratory tests on human and rat leiomyoma cells. In addition, Christman reported the results of subsequent tests on lab animals during the annual meeting of the American Society of Gene Therapy in Seattle on Friday (May 29). The U-M ...Researchers Demonstrate That COX-2 Inhibits Angiogenisis In Tumor Cells
...d director of the divisionof Gastroenterology, and colleagues at the Osaka University School of Medicinein Japan... research builds on earlier work by DuBois and his colleagues thatsuggested aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) helpprevent colon can...University Of Pittsburgh Scientist Discovers How A Novel Vitamin K Stops Cancer Cell Growth
...mentally," said Dr. Carr. Dr. Carr and his colleagues recently reported that Cpd 5 can inhibitliver regeneration in rats that had part of their livers removed. The animalssuffered no toxic side effects. Researchers at UPCI are at the forefront of experimental work usingvitamins A, D and K to pr...Colorado State Research Indicates Two TB Vaccines Show Promise
...illion deaths each year. Since 1992 Orme and his colleagues have not only pursued their own basic research interests, but with support from a grant from the National Institutes of Health have operated a TB vaccine screening program that has examined dozens of experimental vaccines, including the two reported ......tive against metastatic cervicalcancer, Ji and her colleagues developed a line of tumor cells by geneticallyaltering mouse lung cells to include E7. This made the cells similar tocervical cancer cells. She then showed that a tail vein injection of the cancercells could cause lung tumors in mice in two weeks. ...