Tag: "colorectal" at biology news

Selenium Supplements Can Reduce Cancer Rates

...nfidence in these findings." Prostate, esophageal, colorectal and lung cancer rates were among the most dramatic... of neoplastic polyps in the colon, a precursor to colorectal cancer. And in other studies at Cornell, colleagues of Combs' reported in 1995 that animals fed die...

Prostate Cancer's Aggressiveness May Be Predicted Early By The Ratio Of Free To Total PSA

...ermine whether screening tests for prostate, lung, colorectal and ovarian cancers will reduce the number of deaths from these cancers. The Prostate, Lung, Colorectal & Ovarian Cancer Screening Trial (PLCO) will involve 150,000 Americans nationwide, 55 but not yet 75 years of age. Half of the people will receiv...

Jefferson Scientists Find Potential Deadly Effects Of Two Missing Cancer-Suppressor Genes

...e are two of the most commonly altered genes in colorectal cancer and understanding their mechanism in car... of genetically linked hereditary non-polyposis colorectal cancer (HNPCC)--one of the most common human cancer predisposition syndromes (Fishel, R. et al...

Plant-Based Therapies Examined For Colon Cancer Prevention

...sity in New York City for their ability to prevent colorectal cancer,which afflicts some 150,000 Americans each ...), widely used aspirin-like drugs known to prevent colorectal cancer aswell as reduce related deaths by half. Eating diets rich in fruits and vegetables h...

New Molecular Switch Is The Key That Unlocks DNA Repair

...which accounts for some 10 to 15 percent of all colorectal cancers. “We’d like to know why alterations in only two of the five known mismatch repair genes cause cancer,” he says. [The other mismatch repair genes are hMSH3, hMSH6 and hPMS2. They function as protein complexes: hMSH2-...

RNA-Dendritic Cell Combo Shows Promise As A Universal Cancer Vaccine

...al trial, testing the vaccine for breast, lung and colorectal cancers. Thefirst phase of the trial has shown tha...ntigen).CEA is often expressed in breast, lung and colorectal cancer. They mixed thisRNA sequence with dendritic cells and the CEA was produced and displayed on t...

Tiny Worm Reveals Workings Of Suspected Tumor Protein

...e p300 has been implicated in leukemia,gastric and colorectal tumors, much more research is needed to understand itspossible role in cancer, Shi says. Could the entire embryo--a shapeless lump of excess cells--be some kind ofimmature tumor? While this thought tantalizes him, Shi says, there is more toi...

Adults Need To Increase Intake Of Folate; Some Women Should Take More

... showing that increased folate may protect against colorectal cancer do notprovide conclusive evidence of a benefit, the report says. Upper Levels Set The committee set the tolerable upper intake level for vitamin B6 at 100milligrams per day for adults. Intakes above this amount could cause sensoryneuropathy...

Wistar Research Yields Information About Colorectal Cancer Cell Invasion

...y the cells bearing theantigens. In patients with colorectal cancer (CRC), however, the antigensexpressed by their growing tumors do not generally cause sufficient immunesystem responses to prevent the growth and spread of the tumor cells. Studies of the GA733 antigen are part of a $6.6 million program projec...

Researchers Identify A Gene That Causes Juvenile Polyposis

...anding this gene may increase our understanding of colorectal cancer ingeneral, and could provide insights into ... percent ofpancreatic cancers and in 15 percent of colorectal cancers.Howe's research is a work in progress. "We know that this gene causes FJP in a subset of fa...

Relatives Of People with Colorectal Polyps Face Increased Risk For Colorectal Cancer

...ths, or adenomas) face ashigh a risk of developing colorectal cancer as do people who have relatives withcolorec... "Our study may alter the screening approach to colorectal cancer,because it suggests that this population should get colonoscopy rather thansigmoidoscopy, whi...

Doctors Find Lead On Common Genes Which Can Lead To Bowel Cancer

...APC variants 11307K and E1317Q are associated with colorectal tumours, butnot always with a family history. PNAS. 1 September 1998. NOTES TO EDITORS Bowel cancer is the third most common cancer (excluding skin cancer) and thesecond most common cause of cancer death in the UK. It is the commonestnon-smoking r...

Aspirin Decreases Genetic Mutations Associated With Inherited Colon Cancer

...velopment of a particular type of commonhereditary colorectal cancer in those at high risk for the disease. ...lecular mechanism by which aspirin interferes with colorectal cancerdevelopment in those individuals who carry particular gene mutations that makesthem very likel...

Tightly Controlled Protein Destruction Drives The Cell Cycle

...en linked to a number of human diseases, including colorectal andother cancers, Parkinson's disease, Alzheimer's disease, cystic fibrosis, Down'ssyndrome, and less common disorders such as Liddle's syndrome and Angelmansyndrome. A better understanding of ubiquitin-mediated proteolysis, therefore,could form theb...

Press Briefings

...air gene. Individuals with hereditarynonpolyposis colorectal cancer HNPCC often have a defect in a mismatch repairgene. Since endometrial cancer is the second most common type of cancer inthese patients, and occurs in 22-43% of individuals who carry this genemutation, they examined alterations in two mismatch...

Study: Calcium Supplements Appear To Protect Against Colorectal Cancer

....Doctors consider polyps in the colon, also called colorectal adenomas, a strongprecursor to cancer. Researchers found 31 percent of 409 patients randomly selected toreceive 1200 milligrams of calcium carbonate daily developed one or more polypsduring the study. Thirty-eight percent of 423 volunteers wh...

New England Journal Of Medicine Reports Calcium Supplements Help Prevent Polyp Recurrence; DMS Led Study

...ented polyps. "Adenomas or polyps may develop into colorectal cancer. Less than one year intothe study, we saw ...e benign, they are thought to beprecursors of most colorectal cancers and can be removed before progression toinvasive cancer. Colon and rectal cancers (together...

Genes Linked To Early Onset, Location Of Hereditary Colon Cancer

...have identified a mechanism that may explain where colorectal tumors arise and at what age the tumors develop in people with one formof colorectal cancer. The study involved people with hereditary nonpolyposis colorectal cancer (HNPCC), the most c...

Familial Cancer Syndrome Linked to Colorectal Cancer in Younger People

...r) have a family historyconsistent with a familial colorectal cancer syndrome known as hereditarynon-polyposis colorectal cancer (HNPCC), according to researchers at MemorialSloan-Kettering Cancer Center. The study, publ...

Researchers Find How Two Cancer Genes Interact To Cause Malignancy

...ent anddiagnosis of many cancers, including brain, colorectal and endometrial(uterine). Tumor cells with mutations in both myc and ras are likely to have aneven more dramatic increase in the duration of the myc growth signal, Nevinssaid. "The key to developing better therapeutics for cancer," said Nevins, "is ...

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(Date:8/19/2014)... week,s JAMA highlights the importance of physicians ... to treat patients. Written by Robert Vinci, MD, chief ... pediatrics at Boston University School of Medicine and Howard ... examines results of a study published in the same ... doctors can often over-emphasize certain types of data. , ...
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