Tips from the journals of the American Society for Microbiology
...effects such as abscesses. "In order to combat the disease and mitigate serious clinical complications, research has mainly been aimed at developing efficient vaccines," say the researchers. In the study, mice were immunized with a recombinant subunit vaccine containing parts of the th...First ever standards linking climate change, biodiversity and poverty seek global peer review
... are the most immediate and realistic solutions to combat biodiversity loss, reduce poverty and fight climate change," said John-O Niles, CCBA project manager. "The standards will help the private sector and government funding agencies identify multiple-benefit projects that solve three pressing global pro...RNAi delivery system crosses blood-brain barrier to target brain cancer
... is the Trojan warrior released inside the cell to combat the cancer. The plasmid is constructed of genetic material designed to reproduce shRNA, which is then metabolized by a protein in the tumor cell called Dicer. Dicer produces the active RNAi molecule that complements a defined sequence from the EGFR ...... Jones also sees the application of epigenetics to combat disorders caused by aging, providing the opportunity to turn on the genes shut down by the aging process. And the search for the right drugs to undo the epigenetic damage is equally wide-ranging. Jones is involved in research into the utility of a co...Insight into transplant rejection might lead to novel prevention therapies
...gs. Drugs targeting the immune reaction could help combat early lung rejection and its complications, thereby increasing patients' chances of survival following the surgery, the researchers said. Lung transplant recipients with particular variants of a gene called TLR4, which is critical in the lung's defen...Leading science, higher-education and engineering groups urge six improvements to U.S. visa quagmire
...l discoveries. The recommendations are designed to combat "the misperception that the United States does not... become snared in red tape. Scientific advances to combat HIV and AIDS, hunger, terrorism and many other crises will require the insights and contributions of...Botulinum toxin structure offers clues for vaccines/treatments
...rmation can be used to design vaccines or drugs to combat the disease, and, almost as important, help mitigate the fear." There are seven known varieties of botulinum toxin, types A-G. They block the release of neurotransmitters, the chemical messengers nerve cells use to communicate with one another and wi...Wisconsin chemists find a new chink in TB's armor
...ctures interested in developing new antibiotics to combat TB and other diseases such as leprosy, which are caused by similar types of bacteria. "Because we understand the mechanism better, we can design inhibitors of this enzyme," Kiessling says. However, she notes that under the best circumstances, it take...GlaxoSmithKline Drug Discovery and Development Research Grant Program 2004
...aking work toward new pharmaceutical strategies to combat the HIV virus. Applications are now being solicited for 2004 research grants and must be submitted by July 31. For detailed information about the GSK Drug Discovery and Development Research Grant Program, as well as an application, please call 1-888-...Four new research centers to explore link between oceans and human health
...that show great promise for providing new drugs to combat cancer and fight infectious diseases. In order to guard against health threats, and to take advantage of medicinal benefits that oceans might provide, the impact of oceans on human health must be more fully explored." The four centers, their directo...Hemochromatosis, inflammation and anemia
...em itself. Now scientists may have found a way to combat the anemia of chronic diseases by blocking the action of only one gene HFE without having much effect on the rest of the immune response, and without any serious consequences for the organism. HFE is the gene mutated in the common genetic disease ...Conservation International & SC Johnson invest in Ecuador's rainforest to offset climate impacts
...ation, an Ecuadorian conservation organization, to combat global warming, protect the regions' biodiversity and support local communities through the reforestation of degraded forests in northwest Ecuador. SC Johnson's commitment will support the restoration of up to 45 acres of degraded forests along the b...Decoding a sulfate-breathing bug
...s. Says Voordouw: "This is important to help combat the spread of toxic metal ions in the environment at mining sites."...Scientists question reports of massive ant supercolonies in California and Europe
..., has documented instances of both cooperation and combat among colonies in California. And in Argentina - where fighting prevails, according to the UCSD group - Heller observed widespread cooperation among densely populated colonies. Her findings raised questions about the hypothesis that aggressive ants h...Received truth turned on end in cancer research
...aits that make it possible to use the same drug to combat them," hopes Felix Mitelman. The fact that his research team have now turned on end an established truth does not mean that other ongoing research on the significance of genetic factors in the emergence of cancer has also been overturned, he emphasi...Leptin rewires the brain's feeding circuits
...nd obesity, and may ultimately lead to new ways to combat obesity, said Friedman.......ion of genes and thereby develop new strategies to combat human disease....Tony Hunter and Raymond N. DuBois awarded Landon-AACR Prizes for Cancer Research
...r been approved or are being tested in patients to combat tumor formation and growth. "I was surprised and humbled to learn that I'd been chosen to receive the Dorothy P. Landon Prize for Translational Cancer Research. It's a tremendous honor," said Dr. DuBois. "Throughout my career I have been very fortu...Mastectomy dramatically reduces breast cancer risk among women with BRCA1/2 mutations
...ke short-term hormone replacement therapy (HRT) to combat the associated symptoms of menopause without fear of significantly increasing breast cancer risk. Although the removal of the breasts and the ovaries does not completely prevent breast and ovarian cancer, researchers strongly recommend that all wom......t, was to determine how the cells are recruited to combat cancer and other emerging diseases in the body. The Rockefeller scientists are in close contact with clinicians interested in tailoring immune cells -- such as natural killers -- in treating human leukemias. The current Journal of Immunology publica...