UCLA/Caltech scientists develop new gene therapy approach
...gs raise the hope that we can use this approach or combine it with drugs to treat HIV in people -- particularly in persons who have not experienced good results with other forms of treatment," Baltimore said. Now that scientists can introduce siRNAs into the cell, Chen and Baltimore propose that the technolo...Mechanism to overcome Gleevec resistance demonstrated
...lecular mutation, or resistance to Gleevec, we can combine it with a more specific drug that will help overcome that resistance," said Druker. Gleevec targets the activity of CML cells while leaving normal cells alone, resulting in a treatment that is remarkably effective and produces little or no side effec...Acoustic technique could disinfect medical instruments without heat or harsh chemicals
...nism by which the cavitation, pressure and alcohol combine to kill bacteria remains under study. "We don't know exactly how the cells die, but we know the end phenomenon," said Donald Ahearn, professor emeritus of biology at Georgia State University. "Increased pressure and disinfectant molecules are someho...Even green pond scum can suffer from jet lag
...t is quite a trick for a single-celled organism to combine photosynthesis and nitrogen fixation because the two processes are biochemically incompatible. The Taiwanese discovered that the tiny organisms had solved this problem by inventing the practice of moonlighting: They photosynthesize all day and then f...UMass team to study bioremediation of acid, heavy metals from collapsed mind
... a similar abandoned mine in Wales. The group will combine field work, computer modeling, and laboratory research to study the issue over the next five years. In the end, this interdisciplinary group will demonstrate the global importance of using bacteria to clean up the environment. Nsslein, a microbiolog......utional, international teams of scientists who can combine expertise and data sources, from paleontology to morphology, developmental biology, and molecular biology, says Wheeler. The awards will also involve developing software for improved visualization and analysis of extremely large data sets, and outre...Gift creates KSU Human Origins Study Institute
...ll be the focus of the Ferrini Institute. It will combine new knowledge from such fields as biological anthropology, genetics, neuroanatomy, psychology, embryology, and even animal behavior. Stunning discoveries have been made in the past decade, which have greatly illuminated the process of human evolutio...Field Museum plays key role in massive project to map Tree of Life
...rincipal investigator on this project. "Then we'll combine and analyze the resulting large data matrices using new computer software, designed in large part by members of the group." Partners include several American museums and universities (American Museum of Natural History, The Field Museum, George Washi...Tailor-made cancer drugs: Wave of the future?
...e basic components: a phosphate and a sugar, which combine to form the sides of the double helix "ladder," and a base that forms the ladder's "rungs." All variances in DNA, including cancerous mutations, are the result of unique sequencing of the four types of bases, denoted A, G, C and T. Taylor's approach...Funding for global protein database
...H), has awarded a three-year, $15-million grant to combine three of the world's current protein sequence data...atabase, or UniProt, the new, public database will combine the resources of three existing protein databases: SWISS-PROT, TrEMBL and the Protein Information Re...Rolex announces winners of international awards
...l is expanding her conservation network, aiming to combine the efforts of volunteers and experts in the 11 "wattled crane states" of central and southern Africa, while protecting the wetlands on which cranes and many people depend. "Despite the diversity inherent in the Rolex Awards, the Laureates all have i...New screening method may speed hunt for disease-causing genes
...ornia-Davis, said other scientists saw the need to combine QTL and microarray mapping but that Wayne and McIntyre were the first to pull it off. "They were able to merge these two emerging disciplines to derive nontrivial conclusions," he said. The research required Wayne and the technicians in her laborato...New screening technique may speed hunt for genes
...ornia-Davis, said other scientists saw the need to combine QTL and microarray mapping, but that Wayne and McIntyre were the first to pull it off. "They were able to merge these two emerging disciplines to be able to derive nontrivial conclusions," he said. The research required Wayne and the technicians in ...Misfolding the key to protein's ability to kill brain cells
...ease. Strings of amino acids combine to form proteins inside the cell. They are then compressed and folded into a conformation permitting them to function properly. These prion proteins, or PrP, are folded in the endoplasmic...New studies advance scientific knowledge of drinking water disinfection byproducts
...rmed in drinking water when chlorine disinfectants combine with naturally occurring organic matter. Several epidemiology studies have reported a possible association between these byproducts and adverse reproductive outcomes, including spontaneous abortion. Because the existing toxicology data was very lim...$10 Million center for theoretical biological physics created at UCSD by NSF
... for Theoretical Biological Physics, or CTBP, will combine the intellectual resources of the University of California, San Diego's Division of Physical Sciences, the San Diego Supercomputer Center at UCSD, The Scripps Research Institute and The Salk Institute for Biological Studies. It will bring together th...Newly revealed viral structure suggests a continuum in the evolution of viruses
...ray crystallography. Computer modeling was used to combine images of an entire virus particle provided by the relatively low-resolution technique of electron microscopy with the high-resolution molecular structure of the coat protein obtained through X-ray crystallography. The resultant "quasi-atomic" struc...UCLA science profs awarded $1 million Howard Hughes Medical Institute grants
...ought, and how much fun science is." Goldberg will combine an interactive course, "Genetic Engineering in Medicine, Agriculture and Law," with a cutting-edge laboratory experience that will use state-of-the-science genomic technologies to uncover significant genes. The course will teach students how to think...... stem cell resides." The researchers have begun to combine their approaches, analyzing gene activity of the stem cells and the supportive cells at the same time. They noted, however, that it will take the interactive efforts of many groups to pin down the function of each gene. "We hope other groups will tak......r the developing countries it will be necessary to combine the efforts made by some not-for-profit organisations and private funds to support research for the developing world and to link genomic research with vaccine research and other technologies." says Samuel Broder. "It will also be necessary to transfe...