9/11 search-and-rescue dogs exhibit few effects from exposure to disaster sites
...cer and respiratory diseases."The Penn researchers compared the dogs to a control group of search-and-rescue dogs that were trained similarly but not deployed. Although there is no single registry of all dogs deployed to search the 9/11 sites, the Penn researchers identified 212 deployed handlers, and 97 co...Human chromosome 5 final sequence analysis released to public
...ing regions have also stayed remarkably consistent compared with those in mice or fish rather than accumulatin...all sequence, the human and chimpanzee chromosomes compared have some structural differences, including one large section that is flipped backwards in humans co...Picking prostanoids to provide protection
...emonstrated other mark-ers of more severe disease, compared with apoE/ mice. apoE/TP/ mice presented with fewer markers of dis-ease. These data indicate that PGI2 protects against and TXA2 promotes atherosclerosis development. The use of TP antagonists and molecules with PG-like activity may therefore aid in ...A liking for sweets, combined with novelty seeking, may predict alcoholism
... been frequently found to be higher in alcoholics, compared with nonalcoholic control subjects, as well as in patients with a familial form of alcoholism, compared with patients with nonfamilial forms of alcoholism, said Kampov. It is believed that high novelty s...Genetic analysis rewrites salamander's evolutionary history
...ed the genomes, that is, identified the genes, she compared the complete genome sequences with three other known mitochondrial genomes, for a total sample of 27 species. Using Bayesian statistical techniques, she was able to reconstruct a "robust" family tree of the Plethodontid salamanders. One feature that ...Gene expression in liver tumors and patient prognosis
...iations in gene expression in HCC at diagnosis and compared them to patient survival over time. The researchers examined 91 HCC tissues, 60 matched non-tumor surrounding liver tissues, and 18 normal liver samples. They isolated total RNA to derive complementary DNA and characterized each sample's gen...Can an old gene learn new tricks?
The morphological complexity of mammals, as compared to invertebrates, is thought to have arisen through advantageous genetic changes that occurred during the course of evolution. A new research study published in the September issue of Developmental Cell suggests that the evolution of higher-order ve...IBD (Crohn's, Colitis) 'joins' cancer, inflammatory diseases in associated blood vessel growth
...ssel density was significantly higher in CD and UC compared with control mucosa. V3 expression was only spora... a potent angiogenic response in the corneal assay compared to control-derived extracts, they noted. Conclusion The results provide "morphological and functio...Researchers identify distinctive signature for metastatic prostate cancer
... high level of Hedgehog activity in these tissues, compared to benign prostate tissue samples. The researchers also found high levels of Hedgehog pathway activity in rat prostate cancer cells known to be actively metastatic. In contrast, cells that were not metastatic showed low levels of activity. In partic...Blue marlin in gulf have high mercury levels, A&M study shows
... why the mercury levels are so high in blue marlin compared to similar fishes and why so many of them are potentially toxic timebombs. Funded by the McDaniel Charitable Foundation of Santa Fe, Texas, the project aims to find answers to several key questions related to mercury accumulation in the flesh of pela...New research suggests early diet may play key role in protecting against childhood leukaemia
...diets of 328 children diagnosed with leukaemia and compared them with matched controls. "We found that regular consumption of oranges and/or bananas during the first two years of life was associated with a reduced risk of childhood leukaemia," Kwan reports. "These findings are consistent with the protective...Missing genes may help explain why plague bacteria are so deadly
...-like pain if ingested in water or food. They then compared the Y. pseudotuberculosis genome with the DNA sequences of two Y. pestis strains previously sequenced by the Sanger Institute in Cambridge, England. While the comparison revealed a number of genes in the plague bacterium that are not present in its r...Novel IBD therapeutic approaches reported from Washington Univ., Barcelona, LSU at APS meeting
...ade, and suggest that this therapeutic approach be compared with current therapies. Platelet recruitment in intestinal inflammation modulated by ICAM-1, P-selectin, PSGL-1 Researchers from LSU and the University of Muenster studied the mechanisms responsible for platelet-WBC and platelet-endothelial ce...Disruption of protein-folding causes neurodegeneration, mental retardation
...ke cells called neurospheres. The researchers then compared the behaviour of those cells with that of cells that were similar, except that they lacked -galactosidase, which caused them to accumulate GM1. Regardless of whether the researchers added GM1 or the GM1 accumulated because of loss of -galactosiadase,...New research shows air pollution can reduce children's lung function
...at can be exhaled after taking a deep breath -- as compared to children living in communities with cleaner air. In healthy people, lungs grow to full capacity during the teenage years, but typically stop growing at age 18. Then, lung capacity gradually declines. Adults begin to lose lung function by 1 percent...Adaptive changes in the genome may provide insight into the genetics of complex disease
...ronment of modern humans is dramatically different compared to ourancestors who lived just 10,000 years ago. Now we have unlimited access tofast food and super-sized versions of everything. Although the "thrifty genehypothesis" may be overly simplistic, the basic idea that genetic variationthat once helped us...Complex cells likely arose from combination of bacterial and extreme-microbe genomes
...living things." Lake and Rivera analyzed and compared the genomes of 30 microorganisms selected from the three categories (eukaryotes, bacteria and Archaea). All of the microbes contained about the same number of genes. The researchers then used the computer to produce genome combinations that reflect...New research suggests link between maternal diet and childhood leukemia risk
...issue of Cancer Causes and Control. Researchers compared 138 women who each had a child diagnosed with acute lymphoblastic leukemia (ALL) with a control group of 138 women whose children did not have cancer. The children of all the women in the study were matched by sex, age, race, and county of residence ...Do genes respond to global warming?
...s from Yellowstone National Park's Lamar Cave, and compared genetic material extracted from fossil samples taken from different time points over the past 3,000 years to genetic data taken from contemporary animals. Studying these populations in space and time--an approach the authors call "phylochronology"--...Fossils reveal direct link between global warming and genetic diversity in wildlife
...nd genetics For the experiment, the research team compared DNA from voles and pocket gophers living near Lamar Cave with ancient DNA from fossilized rodents that inhabited the area at different times since 1000 B.C. The researchers were particularly interested in animals that were alive during two recent cl...