Surprising 'ultra-conserved' regions discovered in human genome
...uld find new kinds of things when we sequenced the complete genomes of animals, including our own genome, or if it would just be more of the same kinds of things that were already known. Well, it's not just more of the same," Haussler said. The discovery of ultra-conserved elements in the human genome came f...2004 Max Planck Research Prize for Martin Vingron and Eugene W. Myers
...r Science - Software for Analyzing the Genome The complete map of the human genome, which comprises three bil.... This proved to be the key to the assembly of the complete genome. This year, the focus of the Max Planck Research Prize was modified to take particular accoun...Analysis uncovers critical stretches of human genome
...ved in regulating transcription, but if so, it's a complete mystery how they work. What people find most interesting and exciting about these results is that they raise more questions than they answer." For example, said Haussler, the many conserved elements that are not in genes still tend to cluster in grou...Chromosome losses mean poor survival in childhood leukemia
...nsive chemotherapy and their disease had gone into complete remission. All the children had cancers showing the Philadelphia chromosome, an alteration in the genes that indicates a poorer response to treatment. Sixty-one percent of the patients (153), showed secondary chromosome abnormalities; that is, abnor...JGI decodes wood & toxic waste-degrading fungus genome
...emediation applications. Having free access to the complete manifest that the genome provides will enable researchers to realize industrial and societal benefits sooner." White rots are filamentous, or threadlike, wood decay fungi commonly found inhabiting forest detritus and fallen trees. The name derives f...Rb2 expression could play vital role in ovarian cancer Temple University researchers find
...amples and found that 40 percent had a decrease or complete loss of Rb2 protein expression. Giordano discovered the Rb2 gene while working at Temple's Fels Cancer Institute in the early 1990s. "In the samples where the protein was decreased or lost, there was an inverse correlation to the aggressiveness of ...Kinase backgrounder: Iressa discovery part of major kinase project at Dana-Farber
...t to understand cancer, you need to understand the complete pattern of genetic changes in cancer cells that accounts for their malevolent behavior," recalls Meyerson, a molecular and cellular oncology researcher whose chief interest is lung cancer. "Bill said, 'Let's start with the [mutant] kinases, because t...What it Takes: Design principles to broaden participation in SET
...ched in the 1960s in Berkeley, California. (For a complete list of rated programs, see page five.) The BEST Panel also identified a framework of design principles BEST that overlapped among effective programs: Defined outcomes drive the intervention and are successfully accomplished for the entire target po...DFG establishes first German-Sino Research Training Group
...t six per cent of all doctoral students in Germany complete their doctorates in Research Training Groups. Graduates from Research Training Groups are generally more extensively qualified and, on average, two years younger than other doctoral students. Twenty-seven per cent of the participants in Research Trai...Harvard Stem Cell Institute hosts inaugural symposia
...add a central physical location for the institute, complete with laboratory facilities, but does not have specific plans at this point in time. Though some researchers would continue to work in their own labs at different locations, the physical closeness enabled by a central lab facility should allow informa...Seabed secrets in English clay
...s a result of a mass kill by the next anoxic -- or complete lack of oxygen -- event." "There are indications that conditions in the Oxford Clay-sea were extremely dynamic at the time, probably in response to climatic changes," said Kenig. The finding suggests that use of fossils to reconstruct e...Hopkins scientists overcome main obstacle to making tons of short, drug-like proteins
...an. "The process gave us efficient and essentially complete conversion to the modified amino acids. Since the process works the same for all amino acids, you don't have to treat each one separately and then mix them at the end, which speeds things up considerably." Merryman and mentor Rachel Green, Ph.D., an ...Gulf of Maine Ocean Data Partnership announced
...better see the Gulf of Maine in its fullness, as a complete ecosystem. When the system is up and running, we ...currents, the sea floor, and prey to obtain a more complete picture about the behavior of different species and to determine how they might be managed. Data on...Insights on stroke from the peripheral blood suggest ways to develop markers and therapies
...ng stroke. A few drops of peripheral blood provide complete information on DNA, the switching on and off of genes, and the proteins that are synthesized and secreted into the blood after stroke, as well as the effect of inflammation on stroke. But what makes the technique so immensely valuable in understandin...Moderate iron deficiency affects cognitive performance - but iron supplementation improves it
...more anemic a woman was, the longer it took her to complete the tasks. However, supplementation and the subse...memory, attention, and learning tasks) and time to complete the task. This finding has great implications, says Dr. Murray-Kolb, because the prevalence of iron...Evolution's mirror in a fish's spines
...rallel evolutionary changes, among them partial or complete loss of their pelvic spines. These spines are thought to protect the fish from being devoured by predators. As Kingsley points out, however, pelvic spines may be a disadvantage if the fish live in environments that have very low calcium levels availa...Study marks increased trends in infectious disease occurrences in our oceans
...table to specific factors. "Ideally we would have complete records of disease outbreaks for all marine organisms," commented Ward. "However, that is an unrealistic expectation, even today, given that extensive surveys are difficult both in terms of time and money. So, we developed and tested a method to circ...Oldest known evidence of cat taming found in Cyprus, researchers report in Science
...tems believed to be offerings. A small pit with 24 complete sea shells lay nearby. The skeleton's pelvis was damaged, making it difficult to determine the individual's sex. The offerings were relatively rich for time and region, however, implying that he or she enjoyed some degree of social status. "The assoc...Carnegie Mellon U. develops microgel to recover enzymes for manufacturing, research assays
...adding fresh water and heating the solution. "The complete recoverability of the enzymatic activity is encouraging, and we are excited about extending this concept to other enzymes," noted Armitage. In addition to the food and dairy industries, enzymes are used in a wide variety of applications, including DN...More than 300 critically endangered species completely unprotected, new study shows
... of the Earth's land surface is now protected, the complete lack of protection for many of Earth's most threatened species underscores the "gaps" in the protected area system. "Protecting more than 10 percent of the planet's land surface is a major conservation achievement," said Gustavo Fonseca, Executive Vi...